Delayed graft function in renal transplantation : aetiology and impact on graft outcome

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dc.contributor.advisorKahn, Den_ZA
dc.contributor.authorDouie, Walter James Percivalen_ZA
dc.date.accessioned2014-10-24T07:32:08Z
dc.date.available2014-10-24T07:32:08Z
dc.date.issued2001en_ZA
dc.descriptionBibliography: leaves 61-75.en_ZA
dc.description.abstractThe optimal therapy for most patients with end stage renal disease is renal transplantation. This form of therapy results in improved quality of life, decreased medical expense, and perhaps a survival advantage for the recipient. Renal transplantation is however a complex form of therapy which may be associated with significant complications. The most common allograft complication post transplantation is the development of delayed graft function with a reported incidence of between 23 to 34%. This is a costly complication requiring ongoing dialysis and prolonged hospitalization. It also has a significant emotional impact on the patient and their family. Of greater concern though are the reports in the literature which associate delayed graft function with decreased graft survival. With current organ shortages organ donor criteria have been expanded to match the shortage. It is thus imperative that we should understand the mechanisms of graft damage which may result in delayed graft function. A better understanding of the relationship between delayed graft function and graft survival might significantly impact on our practice in certain settings such as in the use of organs harvested from a marginal donor.en_ZA
dc.identifier.apacitationDouie, W. J. P. (2001). <i>Delayed graft function in renal transplantation : aetiology and impact on graft outcome</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Department of Surgery. Retrieved from http://hdl.handle.net/11427/8747en_ZA
dc.identifier.chicagocitationDouie, Walter James Percival. <i>"Delayed graft function in renal transplantation : aetiology and impact on graft outcome."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Department of Surgery, 2001. http://hdl.handle.net/11427/8747en_ZA
dc.identifier.citationDouie, W. 2001. Delayed graft function in renal transplantation : aetiology and impact on graft outcome. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Douie, Walter James Percival AB - The optimal therapy for most patients with end stage renal disease is renal transplantation. This form of therapy results in improved quality of life, decreased medical expense, and perhaps a survival advantage for the recipient. Renal transplantation is however a complex form of therapy which may be associated with significant complications. The most common allograft complication post transplantation is the development of delayed graft function with a reported incidence of between 23 to 34%. This is a costly complication requiring ongoing dialysis and prolonged hospitalization. It also has a significant emotional impact on the patient and their family. Of greater concern though are the reports in the literature which associate delayed graft function with decreased graft survival. With current organ shortages organ donor criteria have been expanded to match the shortage. It is thus imperative that we should understand the mechanisms of graft damage which may result in delayed graft function. A better understanding of the relationship between delayed graft function and graft survival might significantly impact on our practice in certain settings such as in the use of organs harvested from a marginal donor. DA - 2001 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2001 T1 - Delayed graft function in renal transplantation : aetiology and impact on graft outcome TI - Delayed graft function in renal transplantation : aetiology and impact on graft outcome UR - http://hdl.handle.net/11427/8747 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/8747
dc.identifier.vancouvercitationDouie WJP. Delayed graft function in renal transplantation : aetiology and impact on graft outcome. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Department of Surgery, 2001 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/8747en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Surgeryen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherSurgeryen_ZA
dc.titleDelayed graft function in renal transplantation : aetiology and impact on graft outcomeen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMMeden_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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