Development of a polychromatic flow cytometry panel for the evaluation of HIV-specific T cell responses

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dc.contributor.advisorBurgers, Wendyen_ZA
dc.contributor.authorNaicker, Prinolaen_ZA
dc.date.accessioned2015-01-13T04:02:27Z
dc.date.available2015-01-13T04:02:27Z
dc.date.issued2009en_ZA
dc.descriptionIncludes abstract.en_ZA
dc.descriptionIncludes bibliographical references (leaves 99-115).en_ZA
dc.description.abstractInvestigating T cell responses in HIV infection has revealed several correlates of viral control, but their importance is not fully understood. Further studies to understand the relationship between HIV and the immune system are warranted. The advent of polychromatic flow cytometry has allowed for in depth analysis of T cell functions and phenotypes in HIV infection, including the measurement of T cells that can produce multiple immune molecules simultaneously. The aim of this study was to develop a polychromatic flow cytometry panel to measure multiple functional markers, and optimise a stimulation and staining protocol for use in the laboratory.en_ZA
dc.identifier.apacitationNaicker, P. (2009). <i>Development of a polychromatic flow cytometry panel for the evaluation of HIV-specific T cell responses</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Department of Medicine. Retrieved from http://hdl.handle.net/11427/12132en_ZA
dc.identifier.chicagocitationNaicker, Prinola. <i>"Development of a polychromatic flow cytometry panel for the evaluation of HIV-specific T cell responses."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2009. http://hdl.handle.net/11427/12132en_ZA
dc.identifier.citationNaicker, P. 2009. Development of a polychromatic flow cytometry panel for the evaluation of HIV-specific T cell responses. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Naicker, Prinola AB - Investigating T cell responses in HIV infection has revealed several correlates of viral control, but their importance is not fully understood. Further studies to understand the relationship between HIV and the immune system are warranted. The advent of polychromatic flow cytometry has allowed for in depth analysis of T cell functions and phenotypes in HIV infection, including the measurement of T cells that can produce multiple immune molecules simultaneously. The aim of this study was to develop a polychromatic flow cytometry panel to measure multiple functional markers, and optimise a stimulation and staining protocol for use in the laboratory. DA - 2009 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2009 T1 - Development of a polychromatic flow cytometry panel for the evaluation of HIV-specific T cell responses TI - Development of a polychromatic flow cytometry panel for the evaluation of HIV-specific T cell responses UR - http://hdl.handle.net/11427/12132 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/12132
dc.identifier.vancouvercitationNaicker P. Development of a polychromatic flow cytometry panel for the evaluation of HIV-specific T cell responses. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2009 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/12132en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherMedical Virologyen_ZA
dc.titleDevelopment of a polychromatic flow cytometry panel for the evaluation of HIV-specific T cell responsesen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMScen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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