QT-prolonging drugs: Should they ever be used?

dc.contributor.authorOkreglicki, Andrzej
dc.date.accessioned2017-04-12T07:32:24Z
dc.date.available2017-04-12T07:32:24Z
dc.date.issued2005
dc.date.updated2016-01-05T07:42:07Z
dc.description.abstractIf the current stringent conditions of bodies that register and control medicines had been in force for decades, many commonly used drugs (from antibiotics and antihistamines to antipsychotics and antiarrhythmics) would never have reached the consumer market. Nowadays, pre-release findings of QT prolongation are likely to scupper early-phase trials and result in the abandonment of experimental drugs. Post-marketing surveillance has identified a number of commonly used drugs either as causing QT prolongation or associated with increased sudden unexpected deaths.1 Thioridazine (see p. 46 of this issue) is such a drug.
dc.identifier.apacitationOkreglicki, A. (2005). QT-prolonging drugs: Should they ever be used?. <i>South African Journal of Psychiatry</i>, http://hdl.handle.net/11427/24189en_ZA
dc.identifier.chicagocitationOkreglicki, Andrzej "QT-prolonging drugs: Should they ever be used?." <i>South African Journal of Psychiatry</i> (2005) http://hdl.handle.net/11427/24189en_ZA
dc.identifier.citationOkreglicki, A. (2005). QT-prolonging drugs: should they ever be used?: editorial. South African Journal of Psychiatry, 11(2), p-40.
dc.identifier.ris TY - Journal Article AU - Okreglicki, Andrzej AB - If the current stringent conditions of bodies that register and control medicines had been in force for decades, many commonly used drugs (from antibiotics and antihistamines to antipsychotics and antiarrhythmics) would never have reached the consumer market. Nowadays, pre-release findings of QT prolongation are likely to scupper early-phase trials and result in the abandonment of experimental drugs. Post-marketing surveillance has identified a number of commonly used drugs either as causing QT prolongation or associated with increased sudden unexpected deaths.1 Thioridazine (see p. 46 of this issue) is such a drug. DA - 2005 DB - OpenUCT DP - University of Cape Town J1 - South African Journal of Psychiatry LK - https://open.uct.ac.za PB - University of Cape Town PY - 2005 T1 - QT-prolonging drugs: Should they ever be used? TI - QT-prolonging drugs: Should they ever be used? UR - http://hdl.handle.net/11427/24189 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/24189
dc.identifier.vancouvercitationOkreglicki A. QT-prolonging drugs: Should they ever be used?. South African Journal of Psychiatry. 2005; http://hdl.handle.net/11427/24189.en_ZA
dc.language.isoeng
dc.publisher.departmentDivision of Cardiologyen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.sourceSouth African Journal of Psychiatry
dc.source.urihttp://www.sajp.org.za/index.php/sajp
dc.titleQT-prolonging drugs: Should they ever be used?
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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