Mitigation of the inflammatory response to bioprosthetic heart valve tissue through antigen-directed masking
Master Thesis
2009
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University of Cape Town
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Abstract
This research was firstly directed to characterise the immune response to bioprosthetic heart valves in patients as well as in animal models. The study further demonstrated that the glutaraldehyde concentration applied to commercial heart valves is insufficient to mask the antigenicity of the tissue, therefore an method of masking antigens to mitigate the inflammatory response is needed.
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Includes bibliographical references (leaves 143-165).
Reference:
Du Plessis, E. 2009. Mitigation of the inflammatory response to bioprosthetic heart valve tissue through antigen-directed masking. University of Cape Town.