Anti-oesophageal cancer activity in extracts of deep-water Marion Island sponges

Journal Article

2005

Permanent link to this Item
http://hdl.handle.net/11427/24089
Files
Davies-Coleman_Article_2005.pdf (304.92 KB)
Authors
Davies-Coleman, Michael T
Froneman, William
Keyzers, Robert
Whibley, Catherine
Hendricks, Denver
Samaai, Toufiek
McQuaid, Christopher
Journal Title

South African Journal of Science

Link to Journal
http://www.sajs.co.za/
Journal ISSN
Volume Title
Publisher
Publisher

University of Cape Town

Department
Division of Medical Biochemistry
Faculty
Faculty of Health Sciences
License
Series
Abstract
OESOPHAGEAL CANCER IS ONE OF THE most common causes of cancer-related deaths in South African black males. The limited efficacy of chemotherapeutic agents to treat this disease has prompted a search for potential new chemical entities with anticancer properties. We report here on the evidence for anti-oesophageal cancer activity in the methanolic extracts of five species of sponges dredged from a depth of approximately 100 m in the vicinity of Marion Island in the Southern Ocean during the autumn of 2004.
Description

Reference:

Davies-Coleman, M. T., Froneman, W., Keyzers, R. A., Whibley, C., Hendricks, D., Samaai, T., & McQuaid, C. (2005). Anti-oesophageal cancer activity in extracts of deep-water Marion Island sponges: research in action. South African journal of science, 101(11 & 12), p-489.

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