A retrospective histopathological study and selected molecular genetics of archival prostatic cancer tissue

Master Thesis

2005

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University of Cape Town

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Abstract
The aims of this study were to determine the age at presentation and the racial distribution of prostatic adenocarcinoma in the Western Cape region and correlate this with histological grade; to correlate the expression of androgen receptor, bcl-2, p53 and Cox-2 with the Gleason grade of disease and patient demographic data and to establish a method to determine androgen receptor (AR) gene amplification in formalin fixed prostatic carcinoma tissue.
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Includes bibliographical references (leaves 40-44).

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