Detection of human papillomavirus (HPV) and expression of cell-cycle markers in breast carcinoma in a cohort of South African patients

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dc.contributor.advisorGovender, Dhirenen_ZA
dc.contributor.authorFenwick, Sharonen_ZA
dc.date.accessioned2014-07-28T14:51:33Z
dc.date.available2014-07-28T14:51:33Z
dc.date.issued2013en_ZA
dc.descriptionIncludes abstract.
dc.descriptionIncludes bibliographical references.
dc.description.abstractBreast carcinoma is a common cancer in South African women. In the Republic of South Africa, 41 new cases of breast cancer are diagnosed per 100 000 population and the mortality rate is 21 per 100 000 population. Many risk factors have been implicated in the carcinogenesis of this disease; including smoking, family history and hormones, however, this only accounts for about 1/3 of the cases diagnosed. Some studies have implicated Human papillomavirus (HPV) as a possible aetiologic agent in the pathogenesis of breast carcinoma however the results have been inconsistent and sometimes controversial. This study was designed to determine the presence of HPV in breast cancer in a South African cohort and to investigate its influence on the cell cycle. A retrospective and prospective cell block study was undertaken.en_ZA
dc.identifier.apacitationFenwick, S. (2013). <i>Detection of human papillomavirus (HPV) and expression of cell-cycle markers in breast carcinoma in a cohort of South African patients</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Anatomical Pathology. Retrieved from http://hdl.handle.net/11427/3077en_ZA
dc.identifier.chicagocitationFenwick, Sharon. <i>"Detection of human papillomavirus (HPV) and expression of cell-cycle markers in breast carcinoma in a cohort of South African patients."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Anatomical Pathology, 2013. http://hdl.handle.net/11427/3077en_ZA
dc.identifier.citationFenwick, S. 2013. Detection of human papillomavirus (HPV) and expression of cell-cycle markers in breast carcinoma in a cohort of South African patients. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Fenwick, Sharon AB - Breast carcinoma is a common cancer in South African women. In the Republic of South Africa, 41 new cases of breast cancer are diagnosed per 100 000 population and the mortality rate is 21 per 100 000 population. Many risk factors have been implicated in the carcinogenesis of this disease; including smoking, family history and hormones, however, this only accounts for about 1/3 of the cases diagnosed. Some studies have implicated Human papillomavirus (HPV) as a possible aetiologic agent in the pathogenesis of breast carcinoma however the results have been inconsistent and sometimes controversial. This study was designed to determine the presence of HPV in breast cancer in a South African cohort and to investigate its influence on the cell cycle. A retrospective and prospective cell block study was undertaken. DA - 2013 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2013 T1 - Detection of human papillomavirus (HPV) and expression of cell-cycle markers in breast carcinoma in a cohort of South African patients TI - Detection of human papillomavirus (HPV) and expression of cell-cycle markers in breast carcinoma in a cohort of South African patients UR - http://hdl.handle.net/11427/3077 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/3077
dc.identifier.vancouvercitationFenwick S. Detection of human papillomavirus (HPV) and expression of cell-cycle markers in breast carcinoma in a cohort of South African patients. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Anatomical Pathology, 2013 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/3077en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDivision of Anatomical Pathologyen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherin Anatomical Pathologyen_ZA
dc.titleDetection of human papillomavirus (HPV) and expression of cell-cycle markers in breast carcinoma in a cohort of South African patientsen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMScen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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