Development and study of a monoclonal antibody to the human HLA-class II invariant chain

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dc.contributor.advisorProfessor E.B. Dowdle
dc.contributor.authorVeenstra, Hannelore F U
dc.date.accessioned2024-08-16T13:11:48Z
dc.date.available2024-08-16T13:11:48Z
dc.date.issued1991
dc.date.updated2024-08-16T12:07:39Z
dc.description.abstractThe work I present in this thesis was initiated by a request for a monoclonal antibody (MoAb) to the peripheral blood cells of a patient with chronic lymphocytic leukemia (CLL). It was initially hoped that such an antibody, if directed against an idiotypic determinant on the malignant B-cell surface, may prove to be useful therapeutically by virtue of its specificity and limited reactivity. At the time at which the request was made there had already been favourable reports of the use of MoAb's for the management of B-cell derived malignancies
dc.identifier.apacitationVeenstra, H. F. U. (1991). <i>Development and study of a monoclonal antibody to the human HLA-class II invariant chain</i>. (). ,Faculty of Science ,Department of Biological Sciences. Retrieved from http://hdl.handle.net/11427/40516en_ZA
dc.identifier.chicagocitationVeenstra, Hannelore F U. <i>"Development and study of a monoclonal antibody to the human HLA-class II invariant chain."</i> ., ,Faculty of Science ,Department of Biological Sciences, 1991. http://hdl.handle.net/11427/40516en_ZA
dc.identifier.citationVeenstra, H.F.U. 1991. Development and study of a monoclonal antibody to the human HLA-class II invariant chain. . ,Faculty of Science ,Department of Biological Sciences. http://hdl.handle.net/11427/40516en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Veenstra, Hannelore F U AB - The work I present in this thesis was initiated by a request for a monoclonal antibody (MoAb) to the peripheral blood cells of a patient with chronic lymphocytic leukemia (CLL). It was initially hoped that such an antibody, if directed against an idiotypic determinant on the malignant B-cell surface, may prove to be useful therapeutically by virtue of its specificity and limited reactivity. At the time at which the request was made there had already been favourable reports of the use of MoAb's for the management of B-cell derived malignancies DA - 1991 DB - OpenUCT DP - University of Cape Town KW - Antibodies LK - https://open.uct.ac.za PY - 1991 T1 - Development and study of a monoclonal antibody to the human HLA-class II invariant chain TI - Development and study of a monoclonal antibody to the human HLA-class II invariant chain UR - http://hdl.handle.net/11427/40516 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/40516
dc.identifier.vancouvercitationVeenstra HFU. Development and study of a monoclonal antibody to the human HLA-class II invariant chain. []. ,Faculty of Science ,Department of Biological Sciences, 1991 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/40516en_ZA
dc.language.rfc3066eng
dc.publisher.departmentDepartment of Biological Sciences
dc.publisher.facultyFaculty of Science
dc.subjectAntibodies
dc.titleDevelopment and study of a monoclonal antibody to the human HLA-class II invariant chain
dc.typeThesis / Dissertation
dc.type.qualificationlevelMasters
dc.type.qualificationlevelMasters
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