Effectiveness of Personal Protective Equipment for Healthcare Workers Caring for Patients with Filovirus Disease: A Rapid Review

dc.contributor.authorHersi, Monaen_ZA
dc.contributor.authorStevens, Adrienneen_ZA
dc.contributor.authorQuach, Paulineen_ZA
dc.contributor.authorHamel, Candyceen_ZA
dc.contributor.authorThavorn, Kednapaen_ZA
dc.contributor.authorGarritty, Chantelleen_ZA
dc.contributor.authorSkidmore, Beckyen_ZA
dc.contributor.authorVallenas, Constanzaen_ZA
dc.contributor.authorNorris, Susan Len_ZA
dc.contributor.authorEgger, Matthiasen_ZA
dc.date.accessioned2015-11-16T04:09:42Z
dc.date.available2015-11-16T04:09:42Z
dc.date.issued2015en_ZA
dc.description.abstractBACKGROUND: A rapid review, guided by a protocol, was conducted to inform development of the World Health Organization’s guideline on personal protective equipment in the context of the ongoing (2013-present) Western African filovirus disease outbreak, with a focus on health care workers directly caring for patients with Ebola or Marburg virus diseases. METHODS: Electronic databases and grey literature sources were searched. Eligibility criteria initially included comparative studies on Ebola and Marburg virus diseases reported in English or French, but criteria were expanded to studies on other viral hemorrhagic fevers and non-comparative designs due to the paucity of studies. After title and abstract screening (two people to exclude), full-text reports of potentially relevant articles were assessed in duplicate. Fifty-seven percent of extraction information was verified. The Grading of Recommendations Assessment, Development and Evaluation framework was used to inform the quality of evidence assessments. RESULTS: Thirty non-comparative studies (8 related to Ebola virus disease) were located, and 27 provided data on viral transmission. Reporting of personal protective equipment components and infection prevention and control protocols was generally poor. CONCLUSIONS: Insufficient evidence exists to draw conclusions regarding the comparative effectiveness of various types of personal protective equipment. Additional research is urgently needed to determine optimal PPE for health care workers caring for patients with filovirus.en_ZA
dc.identifier.apacitationHersi, M., Stevens, A., Quach, P., Hamel, C., Thavorn, K., Garritty, C., ... Egger, M. (2015). Effectiveness of Personal Protective Equipment for Healthcare Workers Caring for Patients with Filovirus Disease: A Rapid Review. <i>PLoS One</i>, http://hdl.handle.net/11427/15008en_ZA
dc.identifier.chicagocitationHersi, Mona, Adrienne Stevens, Pauline Quach, Candyce Hamel, Kednapa Thavorn, Chantelle Garritty, Becky Skidmore, Constanza Vallenas, Susan L Norris, and Matthias Egger "Effectiveness of Personal Protective Equipment for Healthcare Workers Caring for Patients with Filovirus Disease: A Rapid Review." <i>PLoS One</i> (2015) http://hdl.handle.net/11427/15008en_ZA
dc.identifier.citationHersi, M., Stevens, A., Quach, P., Hamel, C., Thavorn, K., Garritty, C., ... & Moher, D. (2015). Effectiveness of Personal Protective Equipment for Healthcare Workers Caring for Patients with Filovirus Disease: A Rapid Review. PloS one, 10(10), e0140290. doi:10.1371/journal.pone.0140290en_ZA
dc.identifier.ris TY - Journal Article AU - Hersi, Mona AU - Stevens, Adrienne AU - Quach, Pauline AU - Hamel, Candyce AU - Thavorn, Kednapa AU - Garritty, Chantelle AU - Skidmore, Becky AU - Vallenas, Constanza AU - Norris, Susan L AU - Egger, Matthias AB - BACKGROUND: A rapid review, guided by a protocol, was conducted to inform development of the World Health Organization’s guideline on personal protective equipment in the context of the ongoing (2013-present) Western African filovirus disease outbreak, with a focus on health care workers directly caring for patients with Ebola or Marburg virus diseases. METHODS: Electronic databases and grey literature sources were searched. Eligibility criteria initially included comparative studies on Ebola and Marburg virus diseases reported in English or French, but criteria were expanded to studies on other viral hemorrhagic fevers and non-comparative designs due to the paucity of studies. After title and abstract screening (two people to exclude), full-text reports of potentially relevant articles were assessed in duplicate. Fifty-seven percent of extraction information was verified. The Grading of Recommendations Assessment, Development and Evaluation framework was used to inform the quality of evidence assessments. RESULTS: Thirty non-comparative studies (8 related to Ebola virus disease) were located, and 27 provided data on viral transmission. Reporting of personal protective equipment components and infection prevention and control protocols was generally poor. CONCLUSIONS: Insufficient evidence exists to draw conclusions regarding the comparative effectiveness of various types of personal protective equipment. Additional research is urgently needed to determine optimal PPE for health care workers caring for patients with filovirus. DA - 2015 DB - OpenUCT DO - 10.1371/journal.pone.0140290 DP - University of Cape Town J1 - PLoS One LK - https://open.uct.ac.za PB - University of Cape Town PY - 2015 T1 - Effectiveness of Personal Protective Equipment for Healthcare Workers Caring for Patients with Filovirus Disease: A Rapid Review TI - Effectiveness of Personal Protective Equipment for Healthcare Workers Caring for Patients with Filovirus Disease: A Rapid Review UR - http://hdl.handle.net/11427/15008 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/15008
dc.identifier.urihttp://dx.doi.org/10.1371/journal.pone.0140290
dc.identifier.vancouvercitationHersi M, Stevens A, Quach P, Hamel C, Thavorn K, Garritty C, et al. Effectiveness of Personal Protective Equipment for Healthcare Workers Caring for Patients with Filovirus Disease: A Rapid Review. PLoS One. 2015; http://hdl.handle.net/11427/15008.en_ZA
dc.language.isoengen_ZA
dc.publisherPublic Library of Scienceen_ZA
dc.publisher.departmentInstitute of Infectious Disease and Molecular Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rightsThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en_ZA
dc.rights.holder© 2015 Hersi et alen_ZA
dc.rights.urihttp://creativecommons.org/licenses/by/4.0en_ZA
dc.sourcePLoS Oneen_ZA
dc.source.urihttp://journals.plos.org/plosoneen_ZA
dc.subject.otherDatabase searchingen_ZA
dc.subject.otherSafety equipmenten_ZA
dc.subject.otherRespiratorsen_ZA
dc.subject.otherSystematic reviewsen_ZA
dc.subject.otherMarburg hemorrhagic feveren_ZA
dc.subject.otherCrimean-Congo hemorrhagic feveren_ZA
dc.subject.otherEbola hemorrhagic feveren_ZA
dc.subject.otherFilovirusesen_ZA
dc.titleEffectiveness of Personal Protective Equipment for Healthcare Workers Caring for Patients with Filovirus Disease: A Rapid Reviewen_ZA
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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