Role of the SAFE pathway and the mitochondria in HDL cholesterol (and its constituent sphingosine-1-phosphate) induced cardioprotection

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dc.contributor.advisorLecour, Sandrineen_ZA
dc.contributor.authorHacking, Damianen_ZA
dc.date.accessioned2015-01-08T19:48:32Z
dc.date.available2015-01-08T19:48:32Z
dc.date.issued2011en_ZA
dc.description.abstractHigh density lipoprotein cholesterol (HDL) and its component sphingosine-1-phosphate (S1P) protect against myocardial infarction. Recently, the SAFE (survivor activating factor enhancement) pathway, involving tumour necrosis factor (TNF) and the transcription factor signal transducer and activator of transcription 3 (STAT-3), has been identified as a key signalling pathway in cardioprotection, although the end effector remains unclear.en_ZA
dc.identifier.apacitationHacking, D. (2011). <i>Role of the SAFE pathway and the mitochondria in HDL cholesterol (and its constituent sphingosine-1-phosphate) induced cardioprotection</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Cardiology. Retrieved from http://hdl.handle.net/11427/11755en_ZA
dc.identifier.chicagocitationHacking, Damian. <i>"Role of the SAFE pathway and the mitochondria in HDL cholesterol (and its constituent sphingosine-1-phosphate) induced cardioprotection."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Cardiology, 2011. http://hdl.handle.net/11427/11755en_ZA
dc.identifier.citationHacking, D. 2011. Role of the SAFE pathway and the mitochondria in HDL cholesterol (and its constituent sphingosine-1-phosphate) induced cardioprotection. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Hacking, Damian AB - High density lipoprotein cholesterol (HDL) and its component sphingosine-1-phosphate (S1P) protect against myocardial infarction. Recently, the SAFE (survivor activating factor enhancement) pathway, involving tumour necrosis factor (TNF) and the transcription factor signal transducer and activator of transcription 3 (STAT-3), has been identified as a key signalling pathway in cardioprotection, although the end effector remains unclear. DA - 2011 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2011 T1 - Role of the SAFE pathway and the mitochondria in HDL cholesterol (and its constituent sphingosine-1-phosphate) induced cardioprotection TI - Role of the SAFE pathway and the mitochondria in HDL cholesterol (and its constituent sphingosine-1-phosphate) induced cardioprotection UR - http://hdl.handle.net/11427/11755 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/11755
dc.identifier.vancouvercitationHacking D. Role of the SAFE pathway and the mitochondria in HDL cholesterol (and its constituent sphingosine-1-phosphate) induced cardioprotection. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Cardiology, 2011 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/11755en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDivision of Cardiologyen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherCardiologyen_ZA
dc.titleRole of the SAFE pathway and the mitochondria in HDL cholesterol (and its constituent sphingosine-1-phosphate) induced cardioprotectionen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMMeden_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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