A review of living donor liver transplantation: why is regeneration more rapid in the recipient compared to the donor?

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dc.contributor.advisorKahn, Delawiren_ZA
dc.contributor.authorIbirogba, Sheriff Ben_ZA
dc.date.accessioned2015-02-17T13:03:08Z
dc.date.available2015-02-17T13:03:08Z
dc.date.issued2009en_ZA
dc.descriptionIncludes bibliographical references (leaves 54-62).en_ZA
dc.description.abstractLiving donor liver transplantation (LDLT) is now well established and performed on a routine basis in many major centres around the world. LDLT is feasible because of the capacity of both the remnant donor liver and the transplanted partial liver to undergo liver regeneration. However it has been demonstrated that liver regeneration in the recipient is rapid, whereas restoration of liver mass in the donor is delayed. This discrepancy in the rate of regeneration could be due to the presence of hepatotrophic factors and the use of immunosuppression in the recipient. The aims of the studies were to determine if hepatotrophic factors and immunosuppression (Cyclosporine) could modify the restoration of the liver mass after partial hepatectomy in rats.en_ZA
dc.identifier.apacitationIbirogba, S. B. (2009). <i>A review of living donor liver transplantation: why is regeneration more rapid in the recipient compared to the donor?</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Department of Surgery. Retrieved from http://hdl.handle.net/11427/12516en_ZA
dc.identifier.chicagocitationIbirogba, Sheriff B. <i>"A review of living donor liver transplantation: why is regeneration more rapid in the recipient compared to the donor?."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Department of Surgery, 2009. http://hdl.handle.net/11427/12516en_ZA
dc.identifier.citationIbirogba, S. 2009. A review of living donor liver transplantation: why is regeneration more rapid in the recipient compared to the donor?. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Ibirogba, Sheriff B AB - Living donor liver transplantation (LDLT) is now well established and performed on a routine basis in many major centres around the world. LDLT is feasible because of the capacity of both the remnant donor liver and the transplanted partial liver to undergo liver regeneration. However it has been demonstrated that liver regeneration in the recipient is rapid, whereas restoration of liver mass in the donor is delayed. This discrepancy in the rate of regeneration could be due to the presence of hepatotrophic factors and the use of immunosuppression in the recipient. The aims of the studies were to determine if hepatotrophic factors and immunosuppression (Cyclosporine) could modify the restoration of the liver mass after partial hepatectomy in rats. DA - 2009 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2009 T1 - A review of living donor liver transplantation: why is regeneration more rapid in the recipient compared to the donor? TI - A review of living donor liver transplantation: why is regeneration more rapid in the recipient compared to the donor? UR - http://hdl.handle.net/11427/12516 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/12516
dc.identifier.vancouvercitationIbirogba SB. A review of living donor liver transplantation: why is regeneration more rapid in the recipient compared to the donor?. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Department of Surgery, 2009 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/12516en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Surgeryen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherSurgeryen_ZA
dc.titleA review of living donor liver transplantation: why is regeneration more rapid in the recipient compared to the donor?en_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMMeden_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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