Short-latency afferent inhibition during selective finger movement

dc.contributor.authorVoller, Bernhard
dc.contributor.authorSt Clair Gibson, Alan
dc.contributor.authorDambrosia, James
dc.contributor.authorRichardson, Sarah Pirio
dc.contributor.authorLomarev,Mikhail
dc.contributor.authorDang, Nguyet
dc.contributor.authorHallett, Mark
dc.date.accessioned2017-12-06T11:48:20Z
dc.date.available2017-12-06T11:48:20Z
dc.date.issued2005
dc.date.updated2017-11-08T09:43:22Z
dc.description.abstractDuring individual finger movement, two opposite phenomena occur at the level of the central nervous system that could affect other intrinsic hand muscle representations, unintentional co-activation, and surround inhibition (SI). At rest, excitability in the motor cortex (M1) is inhibited at about 20 ms after electric stimulation of a peripheral nerve [short-latency afferent inhibition (SAI)]. We sought to determine whether SAI changes during selective index finger movement. Effects were measured by the response to transcranial magnetic stimulation in two functionally distinct target muscles of the hand [abductor digiti minimi muscle (ADM), first dorsal interosseus muscle (FDI)]. An increase in SAI in the ADM during index finger movement compared to at rest could help explain the genesis of SI. Electrical stimulation was applied to either the little finger (homotopic for ADM, heterotopic for FDI) or the index finger (heterotopic for ADM, homotopic for FDI). During index finger movement, homotopic SAI was present only in the ADM, and the effect of peripheral stimulation was greater when there was less co-activation. Heterotopic SAI found at rest disappeared with movement. We conclude that during movement, homotopic SAI on the muscle in the surround of the intended movement may contribute to SI.
dc.identifierhttp://dx.doi.org/10.1007/s00221-005-0140-9
dc.identifier.apacitationVoller, B., St Clair Gibson, A., Dambrosia, J., Richardson, S. P., , Dang, N., & Hallett, M. (2005). Short-latency afferent inhibition during selective finger movement. <i>Experimental Brain Research</i>, http://hdl.handle.net/11427/26468en_ZA
dc.identifier.chicagocitationVoller, Bernhard, Alan St Clair Gibson, James Dambrosia, Sarah Pirio Richardson, , Nguyet Dang, and Mark Hallett "Short-latency afferent inhibition during selective finger movement." <i>Experimental Brain Research</i> (2005) http://hdl.handle.net/11427/26468en_ZA
dc.identifier.citationVoller, B., Gibson, A. S. C., Dambrosia, J., Richardson, S. P., Lomarev, M., Dang, N., & Hallett, M. (2006). Short-latency afferent inhibition during selective finger movement. Experimental brain research, 169(2), 226-231.
dc.identifier.ris TY - AU - Voller, Bernhard AU - St Clair Gibson, Alan AU - Dambrosia, James AU - Richardson, Sarah Pirio AU - Lomarev,Mikhail AU - Dang, Nguyet AU - Hallett, Mark AB - During individual finger movement, two opposite phenomena occur at the level of the central nervous system that could affect other intrinsic hand muscle representations, unintentional co-activation, and surround inhibition (SI). At rest, excitability in the motor cortex (M1) is inhibited at about 20 ms after electric stimulation of a peripheral nerve [short-latency afferent inhibition (SAI)]. We sought to determine whether SAI changes during selective index finger movement. Effects were measured by the response to transcranial magnetic stimulation in two functionally distinct target muscles of the hand [abductor digiti minimi muscle (ADM), first dorsal interosseus muscle (FDI)]. An increase in SAI in the ADM during index finger movement compared to at rest could help explain the genesis of SI. Electrical stimulation was applied to either the little finger (homotopic for ADM, heterotopic for FDI) or the index finger (heterotopic for ADM, homotopic for FDI). During index finger movement, homotopic SAI was present only in the ADM, and the effect of peripheral stimulation was greater when there was less co-activation. Heterotopic SAI found at rest disappeared with movement. We conclude that during movement, homotopic SAI on the muscle in the surround of the intended movement may contribute to SI. DA - 2005 DB - OpenUCT DP - University of Cape Town J1 - Experimental Brain Research LK - https://open.uct.ac.za PB - University of Cape Town PY - 2005 T1 - Short-latency afferent inhibition during selective finger movement TI - Short-latency afferent inhibition during selective finger movement UR - http://hdl.handle.net/11427/26468 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/26468
dc.identifier.vancouvercitationVoller B, St Clair Gibson A, Dambrosia J, Richardson SP, , Dang N, et al. Short-latency afferent inhibition during selective finger movement. Experimental Brain Research. 2005; http://hdl.handle.net/11427/26468.en_ZA
dc.language.isoeng
dc.publisher.departmentDepartment of Human Biologyen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.sourceExperimental Brain Research
dc.source.urihttps://link.springer.com/journal/221
dc.subject.otherMotor cortex, Afferent inhibition, Surround inhibition
dc.titleShort-latency afferent inhibition during selective finger movement
dc.typeJournal Article
uct.type.filetypeText
uct.type.filetypeImage
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