The effectiveness and safety of micropulse transscleral cyclodiode photocoagulation therapy in glaucoma patients at Groote Schuur Hospital, Cape Town, South Africa

dc.contributor.advisorDu Toit, N
dc.contributor.advisorTinley, C
dc.contributor.authorManyeruke, Stephen
dc.date.accessioned2023-07-04T08:11:01Z
dc.date.available2023-07-04T08:11:01Z
dc.date.issued2023
dc.date.updated2023-07-04T08:08:52Z
dc.description.abstractAim To determine the efficacy and safety of micropulse transscleral cyclodiode photocoagulation laser (MP-TSCPC), in terms of intraocular pressure (IOP) reduction, in refractory glaucoma eyes and in blind glaucomatous eyes that were not on antiglaucoma medications. Method 28 consecutive patients were prospectively recruited. Iridex G6 micropulse laser with its P3 probe was used. Baseline variables, including IOP, number of glaucoma medications and visual acuity (VA)were assessed. Success was set at a minimum of 20% reduction in baseline IOP, or a pressure drop to below 21mmHg at 6 months. Results Twenty-eight eyes of 15 female and 13 male glaucoma patients were enrolled. The mean baseline IOP was 40±11mmHg and the mean post laser pressures were 23±10mmHg at 1 week, 25±11mmHg at 4 weeks, 32±12mmHg at 12 weeks and 27±13mmHg at 24 months, representing a percentage drop of 40%, 35%, 30% and 35%, respectively. There was a reduction of one anti glaucoma agent in 11 (39%) patients. The overall success rate of MP-TSCPC was 71% with no serious complications noted. Conclusion In this small cohort of patients, micropulse transscleral laser cyclophotocoagulation was safe and effective in reducing IOP in glaucoma patients, with a success rate of 71%. Further studies are required to verify this finding.
dc.identifier.apacitationManyeruke, S. (2023). <i>The effectiveness and safety of micropulse transscleral cyclodiode photocoagulation therapy in glaucoma patients at Groote Schuur Hospital, Cape Town, South Africa</i>. (). ,Faculty of Health Sciences ,Division of General Surgery. Retrieved from http://hdl.handle.net/11427/38012en_ZA
dc.identifier.chicagocitationManyeruke, Stephen. <i>"The effectiveness and safety of micropulse transscleral cyclodiode photocoagulation therapy in glaucoma patients at Groote Schuur Hospital, Cape Town, South Africa."</i> ., ,Faculty of Health Sciences ,Division of General Surgery, 2023. http://hdl.handle.net/11427/38012en_ZA
dc.identifier.citationManyeruke, S. 2023. The effectiveness and safety of micropulse transscleral cyclodiode photocoagulation therapy in glaucoma patients at Groote Schuur Hospital, Cape Town, South Africa. . ,Faculty of Health Sciences ,Division of General Surgery. http://hdl.handle.net/11427/38012en_ZA
dc.identifier.ris TY - Master Thesis AU - Manyeruke, Stephen AB - Aim To determine the efficacy and safety of micropulse transscleral cyclodiode photocoagulation laser (MP-TSCPC), in terms of intraocular pressure (IOP) reduction, in refractory glaucoma eyes and in blind glaucomatous eyes that were not on antiglaucoma medications. Method 28 consecutive patients were prospectively recruited. Iridex G6 micropulse laser with its P3 probe was used. Baseline variables, including IOP, number of glaucoma medications and visual acuity (VA)were assessed. Success was set at a minimum of 20% reduction in baseline IOP, or a pressure drop to below 21mmHg at 6 months. Results Twenty-eight eyes of 15 female and 13 male glaucoma patients were enrolled. The mean baseline IOP was 40±11mmHg and the mean post laser pressures were 23±10mmHg at 1 week, 25±11mmHg at 4 weeks, 32±12mmHg at 12 weeks and 27±13mmHg at 24 months, representing a percentage drop of 40%, 35%, 30% and 35%, respectively. There was a reduction of one anti glaucoma agent in 11 (39%) patients. The overall success rate of MP-TSCPC was 71% with no serious complications noted. Conclusion In this small cohort of patients, micropulse transscleral laser cyclophotocoagulation was safe and effective in reducing IOP in glaucoma patients, with a success rate of 71%. Further studies are required to verify this finding. DA - 2023 DB - OpenUCT DP - University of Cape Town KW - general surgery LK - https://open.uct.ac.za PY - 2023 T1 - The effectiveness and safety of micropulse transscleral cyclodiode photocoagulation therapy in glaucoma patients at Groote Schuur Hospital, Cape Town, South Africa TI - The effectiveness and safety of micropulse transscleral cyclodiode photocoagulation therapy in glaucoma patients at Groote Schuur Hospital, Cape Town, South Africa UR - http://hdl.handle.net/11427/38012 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/38012
dc.identifier.vancouvercitationManyeruke S. The effectiveness and safety of micropulse transscleral cyclodiode photocoagulation therapy in glaucoma patients at Groote Schuur Hospital, Cape Town, South Africa. []. ,Faculty of Health Sciences ,Division of General Surgery, 2023 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/38012en_ZA
dc.language.rfc3066eng
dc.publisher.departmentDivision of General Surgery
dc.publisher.facultyFaculty of Health Sciences
dc.subjectgeneral surgery
dc.titleThe effectiveness and safety of micropulse transscleral cyclodiode photocoagulation therapy in glaucoma patients at Groote Schuur Hospital, Cape Town, South Africa
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationlevelMMed
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