The utility of computed tomography for recent-onset partial seizures in childhood

dc.contributor.authorSwingler, George H
dc.contributor.authorWestwood, Anthony T R
dc.contributor.authorIloni, Karen
dc.date.accessioned2017-07-17T09:05:16Z
dc.date.available2017-07-17T09:05:16Z
dc.date.issued2006
dc.date.updated2016-01-12T09:31:09Z
dc.description.abstractObjectives. To determine the diagnostic yield of computed tomography (CT) of the head in children presenting for the first time with partial seizures in a region with a high prevalence of tuberculosis and neurocysticercosis. Design. Prospective cohort study Setting. The secondary-level ambulatory service of Red Cross Children’s Hospital, Cape Town. Subjects. Children aged 6 months - 12 years with a first partial seizure. Outcome measures. Abnormal CT findings; clinically unsuspected abnormal CT findings. Results. Of 118 enrolled children, CT findings were available for 94 (80%). Sixteen (33%) of 49 children scheduled to return later for an initial CT scan failed to do so. Thirty-two scans (34%) were reported normal, 45 (48%) showed single or multiple granulomas, and 17 (18%) showed other findings. All 8 children with persistent specific CT findings were suspected of having the condition before CT scan. Of 68 cases with prospectively recorded clinically expected CT findings, normal scans were expected in 2 cases (3%) and occurred in 33 cases (49%). Conclusions. Routine CT scan for children presenting with a first partial seizure in an area with a high prevalence of neurocysticercosis failed to identify findings other than neurocysticercosis that meaningfully altered clinical management. Assuming a 70% relative reduction of seizures with albendazole treatment for neurocysticercosis, routine CT scanning in the study population would require 11 scans and 5 courses of albendazole to prevent 1 child from having seizures, compared with no CT scans and 11 courses of albendazole with blanket use of albendazole.
dc.identifierhttp://dx.doi.org/10.7196/SAMJ.1291
dc.identifier.apacitationSwingler, G. H., Westwood, A. T. R., & Iloni, K. (2006). The utility of computed tomography for recent-onset partial seizures in childhood. <i>South African Medical Journal</i>, http://hdl.handle.net/11427/24748en_ZA
dc.identifier.chicagocitationSwingler, George H, Anthony T R Westwood, and Karen Iloni "The utility of computed tomography for recent-onset partial seizures in childhood." <i>South African Medical Journal</i> (2006) http://hdl.handle.net/11427/24748en_ZA
dc.identifier.citationSwingler, G., Westwood, A., & Iloni, K. (2006). The utility of computed tomography for recent-onset partial seizures in childhood. South African Medical Journal, 96(9), 941.
dc.identifier.ris TY - Journal Article AU - Swingler, George H AU - Westwood, Anthony T R AU - Iloni, Karen AB - Objectives. To determine the diagnostic yield of computed tomography (CT) of the head in children presenting for the first time with partial seizures in a region with a high prevalence of tuberculosis and neurocysticercosis. Design. Prospective cohort study Setting. The secondary-level ambulatory service of Red Cross Children’s Hospital, Cape Town. Subjects. Children aged 6 months - 12 years with a first partial seizure. Outcome measures. Abnormal CT findings; clinically unsuspected abnormal CT findings. Results. Of 118 enrolled children, CT findings were available for 94 (80%). Sixteen (33%) of 49 children scheduled to return later for an initial CT scan failed to do so. Thirty-two scans (34%) were reported normal, 45 (48%) showed single or multiple granulomas, and 17 (18%) showed other findings. All 8 children with persistent specific CT findings were suspected of having the condition before CT scan. Of 68 cases with prospectively recorded clinically expected CT findings, normal scans were expected in 2 cases (3%) and occurred in 33 cases (49%). Conclusions. Routine CT scan for children presenting with a first partial seizure in an area with a high prevalence of neurocysticercosis failed to identify findings other than neurocysticercosis that meaningfully altered clinical management. Assuming a 70% relative reduction of seizures with albendazole treatment for neurocysticercosis, routine CT scanning in the study population would require 11 scans and 5 courses of albendazole to prevent 1 child from having seizures, compared with no CT scans and 11 courses of albendazole with blanket use of albendazole. DA - 2006 DB - OpenUCT DP - University of Cape Town J1 - South African Medical Journal LK - https://open.uct.ac.za PB - University of Cape Town PY - 2006 T1 - The utility of computed tomography for recent-onset partial seizures in childhood TI - The utility of computed tomography for recent-onset partial seizures in childhood UR - http://hdl.handle.net/11427/24748 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/24748
dc.identifier.vancouvercitationSwingler GH, Westwood ATR, Iloni K. The utility of computed tomography for recent-onset partial seizures in childhood. South African Medical Journal. 2006; http://hdl.handle.net/11427/24748.en_ZA
dc.language.isoeng
dc.publisher.departmentDivision of Child and Adolescent Psychiatryen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.sourceSouth African Medical Journal
dc.source.urihttp://www.samj.org.za/index.php/samj
dc.titleThe utility of computed tomography for recent-onset partial seizures in childhood
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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