Truvada approved as HIV PreP: are South African doctors ready? Survey measuring willingness to prescribe and attitudes, knowledge, and practises regarding HIV PrEP amongst South African based doctors

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dc.contributor.advisorBekker, Linda-Gailen_ZA
dc.contributor.authorFleurs, Llewellynen_ZA
dc.date.accessioned2017-01-19T12:25:02Z
dc.date.available2017-01-19T12:25:02Z
dc.date.issued2016en_ZA
dc.description.abstractHIV prevention has received renewed attention with the release of results from clinical trials dealing with the efficacy and safety of HIV pre-exposure prophylaxis (PrEP), particularly once daily Truvada, within the last decade. The results seemed to suggest that PrEP is efficacious with high levels of adherence. This culminated in the South African Medicines Control Council (MCC) approving use of Truvada as HIV PrEP in December 2015, coupled with the release of SA HIV Clinicians Society guidelines in February 2016. Several issues were found to be involved in prescribing Truvada as PrEP, including clinical monitoring, adherence counselling, and potential for patient behavioural disinhibition. The objective of this thesis is to discuss the results of an online survey administered to South African doctors, on their opinions on the use of Truvada as PreP. Part A deals with the survey protocol and focuses on (1)ethical issues such as approval by the University of Cape Town Research Ethics Committee, and obtaining consent, (2) method of data collection and (3) procedure of data analysis. Part B is a literature review expanding on the topics described in the Background section, including extent of problem posed by HIV, failure to develop a viable HIV vaccine, need for HIV PrEP, review of previous research on HIV PrEP, and the need for a study on South African doctors' opinions on PrEP. Part C is a manuscript that shows the results of the survey, analysis of the data and a discussion on the possible implications.en_ZA
dc.identifier.apacitationFleurs, L. (2016). <i>Truvada approved as HIV PreP: are South African doctors ready? Survey measuring willingness to prescribe and attitudes, knowledge, and practises regarding HIV PrEP amongst South African based doctors</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Department of Public Health and Family Medicine. Retrieved from http://hdl.handle.net/11427/22824en_ZA
dc.identifier.chicagocitationFleurs, Llewellyn. <i>"Truvada approved as HIV PreP: are South African doctors ready? Survey measuring willingness to prescribe and attitudes, knowledge, and practises regarding HIV PrEP amongst South African based doctors."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Department of Public Health and Family Medicine, 2016. http://hdl.handle.net/11427/22824en_ZA
dc.identifier.citationFleurs, L. 2016. Truvada approved as HIV PreP: are South African doctors ready? Survey measuring willingness to prescribe and attitudes, knowledge, and practises regarding HIV PrEP amongst South African based doctors. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Fleurs, Llewellyn AB - HIV prevention has received renewed attention with the release of results from clinical trials dealing with the efficacy and safety of HIV pre-exposure prophylaxis (PrEP), particularly once daily Truvada, within the last decade. The results seemed to suggest that PrEP is efficacious with high levels of adherence. This culminated in the South African Medicines Control Council (MCC) approving use of Truvada as HIV PrEP in December 2015, coupled with the release of SA HIV Clinicians Society guidelines in February 2016. Several issues were found to be involved in prescribing Truvada as PrEP, including clinical monitoring, adherence counselling, and potential for patient behavioural disinhibition. The objective of this thesis is to discuss the results of an online survey administered to South African doctors, on their opinions on the use of Truvada as PreP. Part A deals with the survey protocol and focuses on (1)ethical issues such as approval by the University of Cape Town Research Ethics Committee, and obtaining consent, (2) method of data collection and (3) procedure of data analysis. Part B is a literature review expanding on the topics described in the Background section, including extent of problem posed by HIV, failure to develop a viable HIV vaccine, need for HIV PrEP, review of previous research on HIV PrEP, and the need for a study on South African doctors' opinions on PrEP. Part C is a manuscript that shows the results of the survey, analysis of the data and a discussion on the possible implications. DA - 2016 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2016 T1 - Truvada approved as HIV PreP: are South African doctors ready? Survey measuring willingness to prescribe and attitudes, knowledge, and practises regarding HIV PrEP amongst South African based doctors TI - Truvada approved as HIV PreP: are South African doctors ready? Survey measuring willingness to prescribe and attitudes, knowledge, and practises regarding HIV PrEP amongst South African based doctors UR - http://hdl.handle.net/11427/22824 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/22824
dc.identifier.vancouvercitationFleurs L. Truvada approved as HIV PreP: are South African doctors ready? Survey measuring willingness to prescribe and attitudes, knowledge, and practises regarding HIV PrEP amongst South African based doctors. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Department of Public Health and Family Medicine, 2016 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/22824en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Public Health and Family Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherPublic Healthen_ZA
dc.titleTruvada approved as HIV PreP: are South African doctors ready? Survey measuring willingness to prescribe and attitudes, knowledge, and practises regarding HIV PrEP amongst South African based doctorsen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMPHen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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