Health-Related Quality of Life (HRQoL) of Residents with Persistent Lower Respiratory Symptoms or Asthma Following a Sulphur Stockpile Fire Incident

dc.contributor.authorAdams, Shahieda
dc.contributor.authorRajani, Mayuri
dc.contributor.authorBaatjies, Roslynn
dc.contributor.authorOmar, Faieza
dc.contributor.authorJeebhay, Mohamed Fareed
dc.date.accessioned2022-04-11T11:43:24Z
dc.date.available2022-04-11T11:43:24Z
dc.date.issued2022-03-02
dc.date.updated2022-03-10T14:18:35Z
dc.description.abstractBackground: This study evaluated health-related quality of life (HRQoL) in residents with persistent lower respiratory symptoms (PLRS) or asthma six years after exposure to sulphur dioxide vapours emanating from an ignited sulphur stockpile. Methods:A cross-sectional study was carried out, using interview data collected at three time points (prior to, one- and six-years post incident), medical history, respiratory symptoms and HRQOL using the Medical Outcomes Study Form 36 (SF-36). Results: A total of 246 records, 74 with and 172 without PLRS or asthma, were analysed. The mean age was 42 (SD:12) years in the symptomatic group and 41 (SD:13) years in the asymptomatic group. Mean SF-36 scores were significantly lower for the symptomatic group in the Physical Functioning (24 vs. 39), Role—Physical (33 vs. 48) and General Health (GH) domains (24 vs. 37). Symptomatic residents experienced a significant decline in their Role—Physical (OR = 1.97; CI 1.09, 3.55) and GH (OR = 3.50; CI 1.39, 8.79) at year 6 compared to asymptomatic participants. Residents with co-morbid reactive upper airways dysfunction syndrome demonstrated stronger associations for GH (OR = 7.04; CI 1.61, 30.7) at year 1 and at year 6 (OR = 8.58; CI 1.10, 65.02). Conclusions:This study highlights the long-term adverse impact on HRQoL among residents with PLRS or asthma following a sulphur stockpile fire disaster.
dc.identifierdoi: 10.3390/ijerph19052915
dc.identifier.apacitationAdams, S., Rajani, M., Baatjies, R., Omar, F., & Jeebhay, M. F. (2022). Health-Related Quality of Life (HRQoL) of Residents with Persistent Lower Respiratory Symptoms or Asthma Following a Sulphur Stockpile Fire Incident. http://hdl.handle.net/11427/36331en_ZA
dc.identifier.chicagocitationAdams, Shahieda, Mayuri Rajani, Roslynn Baatjies, Faieza Omar, and Mohamed Fareed Jeebhay "Health-Related Quality of Life (HRQoL) of Residents with Persistent Lower Respiratory Symptoms or Asthma Following a Sulphur Stockpile Fire Incident." (2022) http://hdl.handle.net/11427/36331en_ZA
dc.identifier.citationAdams, S., Rajani, M., Baatjies, R., Omar, F. & Jeebhay, M.F. 2022. Health-Related Quality of Life (HRQoL) of Residents with Persistent Lower Respiratory Symptoms or Asthma Following a Sulphur Stockpile Fire Incident. <i>International Journal of Environmental Research and Public Health.</i> 19(5) http://hdl.handle.net/11427/36331en_ZA
dc.identifier.risTY - Journal Article AU - Adams, Shahieda AU - Rajani, Mayuri AU - Baatjies, Roslynn AU - Omar, Faieza AU - Jeebhay, Mohamed Fareed AB - <i>Background:</i> This study evaluated health-related quality of life (HRQoL) in residents with persistent lower respiratory symptoms (PLRS) or asthma six years after exposure to sulphur dioxide vapours emanating from an ignited sulphur stockpile. <i>Methods:</i> A cross-sectional study was carried out, using interview data collected at three time points (prior to, one- and six-years post incident), medical history, respiratory symptoms and HRQOL using the Medical Outcomes Study Form 36 (SF-36). <i>Results</i>: A total of 246 records, 74 with and 172 without PLRS or asthma, were analysed. The mean age was 42 (SD:12) years in the symptomatic group and 41 (SD:13) years in the asymptomatic group. Mean SF-36 scores were significantly lower for the symptomatic group in the Physical Functioning (24 vs. 39), Role&mdash;Physical (33 vs. 48) and General Health (GH) domains (24 vs. 37). Symptomatic residents experienced a significant decline in their Role&mdash;Physical (OR = 1.97; CI 1.09, 3.55) and GH (OR = 3.50; CI 1.39, 8.79) at year 6 compared to asymptomatic participants. Residents with co-morbid reactive upper airways dysfunction syndrome demonstrated stronger associations for GH (OR = 7.04; CI 1.61, 30.7) at year 1 and at year 6 (OR = 8.58; CI 1.10, 65.02). <i>Conclusions:</i> This study highlights the long-term adverse impact on HRQoL among residents with PLRS or asthma following a sulphur stockpile fire disaster. DA - 2022-03-02 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PY - 2022 T1 - Health-Related Quality of Life (HRQoL) of Residents with Persistent Lower Respiratory Symptoms or Asthma Following a Sulphur Stockpile Fire Incident TI - Health-Related Quality of Life (HRQoL) of Residents with Persistent Lower Respiratory Symptoms or Asthma Following a Sulphur Stockpile Fire Incident UR - http://hdl.handle.net/11427/36331 ER -en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/36331
dc.identifier.urihttps://doi.org/10.3390/ijerph19052915
dc.identifier.vancouvercitationAdams S, Rajani M, Baatjies R, Omar F, Jeebhay MF. Health-Related Quality of Life (HRQoL) of Residents with Persistent Lower Respiratory Symptoms or Asthma Following a Sulphur Stockpile Fire Incident. 2022; http://hdl.handle.net/11427/36331.en_ZA
dc.publisherMultidisciplinary Digital Publishing Institute
dc.rights.licensehttps://creativecommons.org/licenses/by/4.0/
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceInternational Journal of Environmental Research and Public Health
dc.source.journalissue5
dc.source.journalvolume19
dc.source.urihttps://www.mdpi.com/journal/ijerph
dc.subjectpersistent respiratory symptoms
dc.subjectasthma
dc.subjecthealth-related quality of life
dc.subjectupper airways
dc.subjectlower airways
dc.titleHealth-Related Quality of Life (HRQoL) of Residents with Persistent Lower Respiratory Symptoms or Asthma Following a Sulphur Stockpile Fire Incident
dc.typeJournal Article
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