The investigation of the calcium antagonist nifedipine on fetal umbilical artery Doppler waveforms

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dc.contributor.advisorLindow, Stephenen_ZA
dc.contributor.authorPuzey, Martin Stanleyen_ZA
dc.date.accessioned2018-01-30T13:59:51Z
dc.date.available2018-01-30T13:59:51Z
dc.date.issued1992en_ZA
dc.description.abstractThe following thesis will describe the investigation of the effect of nifedipine (a calcium antagonist) on the Doppler flow velocity waveform of the umbilical artery. The thesis is divided into two parts. The first section is a literature review of the three main aspects of the thesis namely: 1. The uteroplacental circulation in humans and the pathophysiology related to this circulation in hypertension and intrauterine growth retardation (IUGR). 2. The biokinetics of nifedipine and a review of the experiments that have been performed using the drug in human and animal models. 3. The principles of Doppler ultrasound and the literature pertaining to its use in the study of the uteroplacental circulation. The second part of the thesis is devoted to the effect of nifedipine on fetal umbilical artery Doppler waveform analysis. In the first ·stage of the investigation the effect of the drug on hypertensive mothers has been examined, and in the second stage the effect on fetuses that have an increased resistance index of the umbilical artery Doppler waveform.en_ZA
dc.identifier.apacitationPuzey, M. S. (1992). <i>The investigation of the calcium antagonist nifedipine on fetal umbilical artery Doppler waveforms</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Department of Obstetrics and Gynaecology. Retrieved from http://hdl.handle.net/11427/27134en_ZA
dc.identifier.chicagocitationPuzey, Martin Stanley. <i>"The investigation of the calcium antagonist nifedipine on fetal umbilical artery Doppler waveforms."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Department of Obstetrics and Gynaecology, 1992. http://hdl.handle.net/11427/27134en_ZA
dc.identifier.citationPuzey, M. 1992. The investigation of the calcium antagonist nifedipine on fetal umbilical artery Doppler waveforms. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Puzey, Martin Stanley AB - The following thesis will describe the investigation of the effect of nifedipine (a calcium antagonist) on the Doppler flow velocity waveform of the umbilical artery. The thesis is divided into two parts. The first section is a literature review of the three main aspects of the thesis namely: 1. The uteroplacental circulation in humans and the pathophysiology related to this circulation in hypertension and intrauterine growth retardation (IUGR). 2. The biokinetics of nifedipine and a review of the experiments that have been performed using the drug in human and animal models. 3. The principles of Doppler ultrasound and the literature pertaining to its use in the study of the uteroplacental circulation. The second part of the thesis is devoted to the effect of nifedipine on fetal umbilical artery Doppler waveform analysis. In the first ·stage of the investigation the effect of the drug on hypertensive mothers has been examined, and in the second stage the effect on fetuses that have an increased resistance index of the umbilical artery Doppler waveform. DA - 1992 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 1992 T1 - The investigation of the calcium antagonist nifedipine on fetal umbilical artery Doppler waveforms TI - The investigation of the calcium antagonist nifedipine on fetal umbilical artery Doppler waveforms UR - http://hdl.handle.net/11427/27134 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/27134
dc.identifier.vancouvercitationPuzey MS. The investigation of the calcium antagonist nifedipine on fetal umbilical artery Doppler waveforms. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Department of Obstetrics and Gynaecology, 1992 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/27134en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Obstetrics and Gynaecologyen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherObstetrics and Gynaecologyen_ZA
dc.subject.otherUltrasonic imagingen_ZA
dc.subject.otherNifedipine - pharmacologyen_ZA
dc.subject.otherUmbilical Arteries - drug effectsen_ZA
dc.subject.otherUltrasonography, Prenatalen_ZA
dc.titleThe investigation of the calcium antagonist nifedipine on fetal umbilical artery Doppler waveformsen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMMeden_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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