Potentiometric and Blood Plasma Simulation Studies of Nickel(II) Complexes of Poly(amino)amido Pentadentate Ligands: Computer Aided Metal-Based Drug Design

dc.contributor.authorOdisitse, Sebusi
dc.contributor.authorJackson, Graham E
dc.date.accessioned2021-10-08T06:20:17Z
dc.date.available2021-10-08T06:20:17Z
dc.date.issued2014
dc.description.abstractThe thermodynamic equilibria of nickel(II) with N,N′-di(aminoethylene)-2,6-pyridinedicarbonylamine (L1), Bis-(N,N-dimethylethyl)-2,6-pyridinedicarboxamide (L2), and N,N′-bis[2(2-pyridyl)-methyl]pyridine-2,6-dicarboxamide (L3) have been studied at 25°C and an ionic strength of 0.15 mol dm−3 by glass electrode potentiometry. The protonation and formation constants added to blood plasma model predict that Cu(II) competes effectively against Ni(II), Zn(II), and Ca(II) for these ligands in vivo.
dc.identifier.apacitationOdisitse, S., & Jackson, G. E. (2014). Potentiometric and Blood Plasma Simulation Studies of Nickel(II) Complexes of Poly(amino)amido Pentadentate Ligands: Computer Aided Metal-Based Drug Design. <i>Bioinorganic Chemistry and Applications</i>, 2014(4), 174 - 177. http://hdl.handle.net/11427/34240en_ZA
dc.identifier.chicagocitationOdisitse, Sebusi, and Graham E Jackson "Potentiometric and Blood Plasma Simulation Studies of Nickel(II) Complexes of Poly(amino)amido Pentadentate Ligands: Computer Aided Metal-Based Drug Design." <i>Bioinorganic Chemistry and Applications</i> 2014, 4. (2014): 174 - 177. http://hdl.handle.net/11427/34240en_ZA
dc.identifier.citationOdisitse, S. & Jackson, G.E. 2014. Potentiometric and Blood Plasma Simulation Studies of Nickel(II) Complexes of Poly(amino)amido Pentadentate Ligands: Computer Aided Metal-Based Drug Design. <i>Bioinorganic Chemistry and Applications.</i> 2014(4):174 - 177. http://hdl.handle.net/11427/34240en_ZA
dc.identifier.issn1565-3633
dc.identifier.issn1687-479X
dc.identifier.ris TY - Journal Article AU - Odisitse, Sebusi AU - Jackson, Graham E AB - The thermodynamic equilibria of nickel(II) with N,N′-di(aminoethylene)-2,6-pyridinedicarbonylamine (L1), Bis-(N,N-dimethylethyl)-2,6-pyridinedicarboxamide (L2), and N,N′-bis[2(2-pyridyl)-methyl]pyridine-2,6-dicarboxamide (L3) have been studied at 25°C and an ionic strength of 0.15 mol dm−3 by glass electrode potentiometry. The protonation and formation constants added to blood plasma model predict that Cu(II) competes effectively against Ni(II), Zn(II), and Ca(II) for these ligands in vivo. DA - 2014 DB - OpenUCT DP - University of Cape Town IS - 4 J1 - Bioinorganic Chemistry and Applications LK - https://open.uct.ac.za PY - 2014 SM - 1565-3633 SM - 1687-479X T1 - Potentiometric and Blood Plasma Simulation Studies of Nickel(II) Complexes of Poly(amino)amido Pentadentate Ligands: Computer Aided Metal-Based Drug Design TI - Potentiometric and Blood Plasma Simulation Studies of Nickel(II) Complexes of Poly(amino)amido Pentadentate Ligands: Computer Aided Metal-Based Drug Design UR - http://hdl.handle.net/11427/34240 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/34240
dc.identifier.vancouvercitationOdisitse S, Jackson GE. Potentiometric and Blood Plasma Simulation Studies of Nickel(II) Complexes of Poly(amino)amido Pentadentate Ligands: Computer Aided Metal-Based Drug Design. Bioinorganic Chemistry and Applications. 2014;2014(4):174 - 177. http://hdl.handle.net/11427/34240.en_ZA
dc.language.isoeng
dc.publisher.departmentDepartment of Chemistry
dc.publisher.facultyFaculty of Science
dc.sourceBioinorganic Chemistry and Applications
dc.source.journalissue4
dc.source.journalvolume2014
dc.source.pagination174 - 177
dc.source.urihttps://dx.doi.org/10.1155/2014/863612
dc.subject.otherArticle Subject
dc.subject.otherChemistry
dc.subject.otherQ
dc.subject.otherQD146-197
dc.subject.otherQD1-999
dc.subject.otherResearch Article
dc.subject.otherInorganic chemistry
dc.subject.otherScience
dc.titlePotentiometric and Blood Plasma Simulation Studies of Nickel(II) Complexes of Poly(amino)amido Pentadentate Ligands: Computer Aided Metal-Based Drug Design
dc.typeJournal Article
uct.type.publicationResearch
uct.type.resourceJournal Article
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