Measurement properties and responsiveness of the EQ-5D-Y-5L compared to the EQ-5D-Y-3L in children and adolescents receiving acute orthopaedic care

dc.contributor.authorVerstraete, Janine
dc.contributor.authorMarthinus, Zara
dc.contributor.authorDix-Peek, Stewart
dc.contributor.authorScott, Des
dc.date.accessioned2022-04-08T08:20:04Z
dc.date.available2022-04-08T08:20:04Z
dc.date.issued2022-02-17
dc.date.updated2022-02-20T04:19:10Z
dc.description.abstractObjective The aim of this study is a head-to-head comparison of the instrument performance and responsiveness of the EQ-5D-Y-3L and the expanded English version of the EQ-5D-Y-5L in children/adolescents receiving acute orthopaedic management in South Africa. Methods Children/adolescents aged 8–15 years completed the EQ-5D-Y-5L, EQ-5D-Y-3L, self-rated health (SRH) question and PedsQL at baseline. The EQ-5D-Y-5L, EQ-5D-Y-3L and SRH question were repeated after 24 and 48 h. Performance of the EQ-5D-Y-5L and EQ-5D-Y-3L was determined by comparing feasibility (missing responses), redistribution of dimensions responses, discriminatory power, concurrent validity, and responsiveness. Results Eighty-three children/adolescents completed baseline measures and seventy-one at all three time-points. Reporting of 11111 decreased by 20% from the EQ-5D-Y-3L to the EQ-5D-Y-5L. Informativity of dimensions improved on average by 0.267 on the EQ-5D-Y-5L with similar evenness. There was a range of 11–27% inconsistent responses when moving from the EQ-5D-Y-3L to the EQ-5D-Y-5L. There was a low to moderate and significant association on the EQ-5D-Y-3L and EQ-5D-Y-5L to similar items on the PedsQL and SRH scores. Percentage change over time was greater for the EQ-5D-Y-5L (range 0–182%) than EQ-5D-Y-3L (range 0–100%) with the largest reduction for both measures between 0 and 48 h. For those who respondents who showed an improved SRH the EQ-5D-Y-5L and EQ-5D-Y-3L showed significant paired differences. Conclusion The English version of the EQ-5D-Y-5L appears to be a valid and responsive extension of the EQ-5D-Y-3L for children receiving acute orthopaedic management. The expanded levels notably reduce the ceiling effect and has greater discriminatory power. Concurrent validity of the EQ-5D-Y-3L and EQ-5D-Y-5L was low to moderate with similar PedsQL items and SRH. The EQ-5D-Y-5L generally showed greater change than the EQ-5D-Y-3L across all dimensions with the greatest change observed for 0–48 h. Responsiveness was comparable across the EQ-5D-Y-3L and EQ-5D-Y-5L for those with improved SRH. Greater sensitivity to change may be observed on comparison of utility scores, once preference-based value sets are available for the EQ-5D-Y-5L.en_US
dc.identifier.apacitationVerstraete, J., Marthinus, Z., Dix-Peek, S., & Scott, D. (2022). Measurement properties and responsiveness of the EQ-5D-Y-5L compared to the EQ-5D-Y-3L in children and adolescents receiving acute orthopaedic care. <i>Health and Quality of Life Outcomes</i>, 17(1), 28. http://hdl.handle.net/11427/36297en_ZA
dc.identifier.chicagocitationVerstraete, Janine, Zara Marthinus, Stewart Dix-Peek, and Des Scott "Measurement properties and responsiveness of the EQ-5D-Y-5L compared to the EQ-5D-Y-3L in children and adolescents receiving acute orthopaedic care." <i>Health and Quality of Life Outcomes</i> 17, 1. (2022): 28. http://hdl.handle.net/11427/36297en_ZA
dc.identifier.citationVerstraete, J., Marthinus, Z., Dix-Peek, S. & Scott, D. 2022. Measurement properties and responsiveness of the EQ-5D-Y-5L compared to the EQ-5D-Y-3L in children and adolescents receiving acute orthopaedic care. <i>Health and Quality of Life Outcomes.</i> 17(1):28. http://hdl.handle.net/11427/36297en_ZA
dc.identifier.ris TY - Journal Article AU - Verstraete, Janine AU - Marthinus, Zara AU - Dix-Peek, Stewart AU - Scott, Des AB - Objective The aim of this study is a head-to-head comparison of the instrument performance and responsiveness of the EQ-5D-Y-3L and the expanded English version of the EQ-5D-Y-5L in children/adolescents receiving acute orthopaedic management in South Africa. Methods Children/adolescents aged 8–15 years completed the EQ-5D-Y-5L, EQ-5D-Y-3L, self-rated health (SRH) question and PedsQL at baseline. The EQ-5D-Y-5L, EQ-5D-Y-3L and SRH question were repeated after 24 and 48 h. Performance of the EQ-5D-Y-5L and EQ-5D-Y-3L was determined by comparing feasibility (missing responses), redistribution of dimensions responses, discriminatory power, concurrent validity, and responsiveness. Results Eighty-three children/adolescents completed baseline measures and seventy-one at all three time-points. Reporting of 11111 decreased by 20% from the EQ-5D-Y-3L to the EQ-5D-Y-5L. Informativity of dimensions improved on average by 0.267 on the EQ-5D-Y-5L with similar evenness. There was a range of 11–27% inconsistent responses when moving from the EQ-5D-Y-3L to the EQ-5D-Y-5L. There was a low to moderate and significant association on the EQ-5D-Y-3L and EQ-5D-Y-5L to similar items on the PedsQL and SRH scores. Percentage change over time was greater for the EQ-5D-Y-5L (range 0–182%) than EQ-5D-Y-3L (range 0–100%) with the largest reduction for both measures between 0 and 48 h. For those who respondents who showed an improved SRH the EQ-5D-Y-5L and EQ-5D-Y-3L showed significant paired differences. Conclusion The English version of the EQ-5D-Y-5L appears to be a valid and responsive extension of the EQ-5D-Y-3L for children receiving acute orthopaedic management. The expanded levels notably reduce the ceiling effect and has greater discriminatory power. Concurrent validity of the EQ-5D-Y-3L and EQ-5D-Y-5L was low to moderate with similar PedsQL items and SRH. The EQ-5D-Y-5L generally showed greater change than the EQ-5D-Y-3L across all dimensions with the greatest change observed for 0–48 h. Responsiveness was comparable across the EQ-5D-Y-3L and EQ-5D-Y-5L for those with improved SRH. Greater sensitivity to change may be observed on comparison of utility scores, once preference-based value sets are available for the EQ-5D-Y-5L. DA - 2022-02-17 DB - OpenUCT DP - University of Cape Town IS - 1 J1 - Health and Quality of Life Outcomes KW - Orthopaedic KW - Fracture KW - Surgery KW - Children KW - Adolescents KW - Youth KW - Health related quality of life KW - EQ-5D-Y KW - Three level KW - Five level KW - EQ-5D-Y-5L LK - https://open.uct.ac.za PY - 2022 T1 - Measurement properties and responsiveness of the EQ-5D-Y-5L compared to the EQ-5D-Y-3L in children and adolescents receiving acute orthopaedic care TI - Measurement properties and responsiveness of the EQ-5D-Y-5L compared to the EQ-5D-Y-3L in children and adolescents receiving acute orthopaedic care UR - http://hdl.handle.net/11427/36297 ER - en_ZA
dc.identifier.urihttps://doi.org/10.1186/s12955-022-01938-6
dc.identifier.urihttp://hdl.handle.net/11427/36297
dc.identifier.vancouvercitationVerstraete J, Marthinus Z, Dix-Peek S, Scott D. Measurement properties and responsiveness of the EQ-5D-Y-5L compared to the EQ-5D-Y-3L in children and adolescents receiving acute orthopaedic care. Health and Quality of Life Outcomes. 2022;17(1):28. http://hdl.handle.net/11427/36297.en_ZA
dc.language.isoenen_US
dc.language.rfc3066en
dc.publisher.departmentDivision of Pulmonologyen_US
dc.publisher.facultyFaculty of Health Sciencesen_US
dc.rights.holderThe Author(s)
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_US
dc.sourceHealth and Quality of Life Outcomesen_US
dc.source.journalissue1en_US
dc.source.journalvolume17en_US
dc.source.pagination28en_US
dc.source.urihttps://hqlo.biomedcentral.com/
dc.subjectOrthopaedicen_US
dc.subjectFractureen_US
dc.subjectSurgeryen_US
dc.subjectChildrenen_US
dc.subjectAdolescentsen_US
dc.subjectYouthen_US
dc.subjectHealth related quality of lifeen_US
dc.subjectEQ-5D-Yen_US
dc.subjectThree levelen_US
dc.subjectFive levelen_US
dc.subjectEQ-5D-Y-5Len_US
dc.titleMeasurement properties and responsiveness of the EQ-5D-Y-5L compared to the EQ-5D-Y-3L in children and adolescents receiving acute orthopaedic careen_US
dc.typeJournal Articleen_US
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