Birth prevalence of ano-rectal malformations for the Western Cape Province, South Africa

dc.contributor.advisorNumanoglu, Alpen_ZA
dc.contributor.authorTheron, André Pieteren_ZA
dc.date.accessioned2016-08-19T13:17:31Z
dc.date.available2016-08-19T13:17:31Z
dc.date.issued2016en_ZA
dc.description.abstractBackground: Anorectal malformations (ARMs) are a major birth anomaly worldwide. South Africa has ethnically and geologically diverse populations. A recent publication indicated an increased birth prevalence of ARMs in the Witwatersrand referral area between 2005 and 2010. The purpose of this study was to determine the birth prevalence of ARM and its various sub - types in the Western Cape referral district over an 8 year period Methods: For an eight year period from 01 January 2005 to 31 December 2012; retrospective data was collected from the Paediatric Surgical Departments of Red Cross War Memorial Children's Hospital, Tygerberg Children's Hospital as well as the private sector health registries. The number of live births per year for a specific municipal district was obtained from the National Department of Health. The Chi square for trend test was used to determine statistical significance. Results: The birth prevalence for ARM in the Western Cape Province in 2012 was shown to be 1:5572 live births (1.79/10 000 live births). The West Coast Municipality district had the highest average birth prevalence rate of 1:3063 (3 .26/10 000) live births for years studied. There was a male predominance (1.6:1), the most common ARM was the vestibular fistula (19.2%) and in 26% of the patients there was an initial delay in the diagnosis. Conclusion: This study has provided some recent data for ARMs for the Western Cape Province. There was no statistical significant change in the prevalence of ARMs over the eight year period for the Western Cape Province as well as in any of the individual six municipal health districts. ( χ2 for trend p=0.52) . The number of delayed diagnosis of ARM is of concern.en_ZA
dc.identifier.apacitationTheron, A. P. (2016). <i>Birth prevalence of ano-rectal malformations for the Western Cape Province, South Africa</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Paediatric Surgery. Retrieved from http://hdl.handle.net/11427/21374en_ZA
dc.identifier.chicagocitationTheron, André Pieter. <i>"Birth prevalence of ano-rectal malformations for the Western Cape Province, South Africa."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Paediatric Surgery, 2016. http://hdl.handle.net/11427/21374en_ZA
dc.identifier.citationTheron, A. 2016. Birth prevalence of ano-rectal malformations for the Western Cape Province, South Africa. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Theron, André Pieter AB - Background: Anorectal malformations (ARMs) are a major birth anomaly worldwide. South Africa has ethnically and geologically diverse populations. A recent publication indicated an increased birth prevalence of ARMs in the Witwatersrand referral area between 2005 and 2010. The purpose of this study was to determine the birth prevalence of ARM and its various sub - types in the Western Cape referral district over an 8 year period Methods: For an eight year period from 01 January 2005 to 31 December 2012; retrospective data was collected from the Paediatric Surgical Departments of Red Cross War Memorial Children's Hospital, Tygerberg Children's Hospital as well as the private sector health registries. The number of live births per year for a specific municipal district was obtained from the National Department of Health. The Chi square for trend test was used to determine statistical significance. Results: The birth prevalence for ARM in the Western Cape Province in 2012 was shown to be 1:5572 live births (1.79/10 000 live births). The West Coast Municipality district had the highest average birth prevalence rate of 1:3063 (3 .26/10 000) live births for years studied. There was a male predominance (1.6:1), the most common ARM was the vestibular fistula (19.2%) and in 26% of the patients there was an initial delay in the diagnosis. Conclusion: This study has provided some recent data for ARMs for the Western Cape Province. There was no statistical significant change in the prevalence of ARMs over the eight year period for the Western Cape Province as well as in any of the individual six municipal health districts. ( χ2 for trend p=0.52) . The number of delayed diagnosis of ARM is of concern. DA - 2016 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2016 T1 - Birth prevalence of ano-rectal malformations for the Western Cape Province, South Africa TI - Birth prevalence of ano-rectal malformations for the Western Cape Province, South Africa UR - http://hdl.handle.net/11427/21374 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/21374
dc.identifier.vancouvercitationTheron AP. Birth prevalence of ano-rectal malformations for the Western Cape Province, South Africa. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Paediatric Surgery, 2016 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/21374en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDivision of Paediatric Surgeryen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherPaediatric Surgeryen_ZA
dc.titleBirth prevalence of ano-rectal malformations for the Western Cape Province, South Africaen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMMeden_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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