Association between parental psychopathology and suicidal behavior among adult offspring: results from the cross-sectional South African Stress and Health survey

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dc.contributor.authorAtwoli, Lukoye
dc.contributor.authorNock, Matthew K
dc.contributor.authorWilliams, David R
dc.contributor.authorStein, Dan J
dc.date.accessioned2015-07-30T04:00:15Z
dc.date.available2015-07-30T04:00:15Z
dc.date.issued2014-03-04
dc.date.updated2015-01-15T17:58:10Z
dc.description.abstractAbstract Background Prior studies have demonstrated a link between parental psychopathology and offspring suicidal behavior. However, it remains unclear what aspects of suicidal behavior among adult offspring are predicted by specific parental mental disorders, especially in Africa. This study set out to investigate the association between parental psychopathology and suicidal behavior among their adult offspring in a South African general population sample. Method Parental psychopathology and suicidal behavior in offspring were assessed using structured interviews among 4,315 respondents from across South Africa. The WHO CIDI was used to collect data on suicidal behavior, while the Family History Research Diagnostic Criteria Interview was used to assess prior parental psychopathology. Bivariate and multivariate survival models tested the associations between the type and number parental mental disorders (including suicide) and lifetime suicidal behavior in the offspring. Associations between a range of parental disorders and the onset of subsequent suicidal behavior (suicidal ideation, plans, and attempts) among adult offspring were tested. Results The presence of parental psychopathology significantly increased the odds of suicidal behavior among their adult offspring. More specifically, parental panic disorder was associated with offspring suicidal ideation, while parental panic disorder, generalized anxiety disorder and suicide were significantly associated with offspring suicide attempts. Among those with suicidal ideation, none of the tested forms of parental psychopathology was associated with having suicide plans or attempts. There was a dose–response relationship between the number of parental disorders and odds of suicidal ideation. Conclusions Parental psychopathology increases the odds of suicidal behavior among their adult offspring in the South African context, replicating results found in other regions. Specific parental disorders predicted the onset and persistence of suicidal ideation or attempts in their offspring. Further research into these associations is recommended in order to determine the mechanisms through which parent psychopathology increases the odds of suicidal behavior among offspring.
dc.identifier.apacitationAtwoli, L., Nock, M. K., Williams, D. R., & Stein, D. J. (2014). Association between parental psychopathology and suicidal behavior among adult offspring: results from the cross-sectional South African Stress and Health survey. <i>BMC Psychiatry</i>, http://hdl.handle.net/11427/13609en_ZA
dc.identifier.chicagocitationAtwoli, Lukoye, Matthew K Nock, David R Williams, and Dan J Stein "Association between parental psychopathology and suicidal behavior among adult offspring: results from the cross-sectional South African Stress and Health survey." <i>BMC Psychiatry</i> (2014) http://hdl.handle.net/11427/13609en_ZA
dc.identifier.citationAtwoli, L., Nock, M. K., Williams, D. R., & Stein, D. J. (2014). Association between parental psychopathology and suicidal behavior among adult offspring: results from the cross-sectional South African Stress and Health survey. BMC psychiatry, 14(1), 65.
dc.identifier.ris TY - Journal Article AU - Atwoli, Lukoye AU - Nock, Matthew K AU - Williams, David R AU - Stein, Dan J AB - Abstract Background Prior studies have demonstrated a link between parental psychopathology and offspring suicidal behavior. However, it remains unclear what aspects of suicidal behavior among adult offspring are predicted by specific parental mental disorders, especially in Africa. This study set out to investigate the association between parental psychopathology and suicidal behavior among their adult offspring in a South African general population sample. Method Parental psychopathology and suicidal behavior in offspring were assessed using structured interviews among 4,315 respondents from across South Africa. The WHO CIDI was used to collect data on suicidal behavior, while the Family History Research Diagnostic Criteria Interview was used to assess prior parental psychopathology. Bivariate and multivariate survival models tested the associations between the type and number parental mental disorders (including suicide) and lifetime suicidal behavior in the offspring. Associations between a range of parental disorders and the onset of subsequent suicidal behavior (suicidal ideation, plans, and attempts) among adult offspring were tested. Results The presence of parental psychopathology significantly increased the odds of suicidal behavior among their adult offspring. More specifically, parental panic disorder was associated with offspring suicidal ideation, while parental panic disorder, generalized anxiety disorder and suicide were significantly associated with offspring suicide attempts. Among those with suicidal ideation, none of the tested forms of parental psychopathology was associated with having suicide plans or attempts. There was a dose–response relationship between the number of parental disorders and odds of suicidal ideation. Conclusions Parental psychopathology increases the odds of suicidal behavior among their adult offspring in the South African context, replicating results found in other regions. Specific parental disorders predicted the onset and persistence of suicidal ideation or attempts in their offspring. Further research into these associations is recommended in order to determine the mechanisms through which parent psychopathology increases the odds of suicidal behavior among offspring. DA - 2014-03-04 DB - OpenUCT DO - 10.1186/1471-244X-14-65 DP - University of Cape Town J1 - BMC Psychiatry LK - https://open.uct.ac.za PB - University of Cape Town PY - 2014 T1 - Association between parental psychopathology and suicidal behavior among adult offspring: results from the cross-sectional South African Stress and Health survey TI - Association between parental psychopathology and suicidal behavior among adult offspring: results from the cross-sectional South African Stress and Health survey UR - http://hdl.handle.net/11427/13609 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/13609
dc.identifier.urihttp://dx.doi.org/10.1186/1471-244X-14-65
dc.identifier.vancouvercitationAtwoli L, Nock MK, Williams DR, Stein DJ. Association between parental psychopathology and suicidal behavior among adult offspring: results from the cross-sectional South African Stress and Health survey. BMC Psychiatry. 2014; http://hdl.handle.net/11427/13609.en_ZA
dc.language.rfc3066en
dc.publisher.departmentDepartment of Psychiatry and Mental Healthen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution License*
dc.rights.holderAtwoli et al.; licensee BioMed Central Ltd.
dc.rights.urihttp://creativecommons.org/licenses/by/2.0*
dc.sourceBMC Psychiatryen_ZA
dc.source.urihttp://www.biomedcentral.com/bmcpsychiatry/
dc.subject.otherSuicideen_ZA
dc.subject.otherParental psychopathologyen_ZA
dc.subject.otherSouth Africaen_ZA
dc.titleAssociation between parental psychopathology and suicidal behavior among adult offspring: results from the cross-sectional South African Stress and Health survey
dc.typeJournal Articleen_ZA
uct.type.filetype
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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