Studies on the degradation of haemoglobin

dc.contributor.advisorKench, J E
dc.contributor.authorGreen, Margaret
dc.date.accessioned2020-06-10T08:26:37Z
dc.date.available2020-06-10T08:26:37Z
dc.date.issued1966
dc.date.updated2020-04-06T19:01:27Z
dc.description.abstractThe chemical relationship which exists between haemoglobin and bile pigments was first established in 1933, when, after monumental studies covering a period of 24 years, Hans Fischer and his colleagues succeeded in synthesizing bile pigments and protoporphyrin. He thereby demonstrated the fundamental tetrapyrrolic structure which is common to both haem and bilirubin. Prior to this, in vivo experiments on dogs performed by Mann, Sheard, Bollman and Blades showed that haemoglobin, injected into the arterial blood of the spleen or bone-marrow, produced a rise in the bilirubin content of the venous blood. Haematin was also evident in both arterial and venous blood.
dc.identifier.apacitationGreen, M. (1966). <i>Studies on the degradation of haemoglobin</i>. (). ,Faculty of Health Sciences ,Division of Medical Biochemistry. Retrieved from http://hdl.handle.net/11427/32056en_ZA
dc.identifier.chicagocitationGreen, Margaret. <i>"Studies on the degradation of haemoglobin."</i> ., ,Faculty of Health Sciences ,Division of Medical Biochemistry, 1966. http://hdl.handle.net/11427/32056en_ZA
dc.identifier.citationGreen, M. 1966. Studies on the degradation of haemoglobin. . ,Faculty of Health Sciences ,Division of Medical Biochemistry. http://hdl.handle.net/11427/32056en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Green, Margaret AB - The chemical relationship which exists between haemoglobin and bile pigments was first established in 1933, when, after monumental studies covering a period of 24 years, Hans Fischer and his colleagues succeeded in synthesizing bile pigments and protoporphyrin. He thereby demonstrated the fundamental tetrapyrrolic structure which is common to both haem and bilirubin. Prior to this, in vivo experiments on dogs performed by Mann, Sheard, Bollman and Blades showed that haemoglobin, injected into the arterial blood of the spleen or bone-marrow, produced a rise in the bilirubin content of the venous blood. Haematin was also evident in both arterial and venous blood. DA - 1966 DB - OpenUCT DP - University of Cape Town KW - Medical Biochemistry KW - Hemoglobins LK - https://open.uct.ac.za PY - 1966 T1 - Studies on the degradation of haemoglobin TI - Studies on the degradation of haemoglobin UR - http://hdl.handle.net/11427/32056 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/32056
dc.identifier.vancouvercitationGreen M. Studies on the degradation of haemoglobin. []. ,Faculty of Health Sciences ,Division of Medical Biochemistry, 1966 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/32056en_ZA
dc.language.rfc3066eng
dc.publisher.departmentDivision of Medical Biochemistry
dc.publisher.facultyFaculty of Health Sciences
dc.subjectMedical Biochemistry
dc.subjectHemoglobins
dc.titleStudies on the degradation of haemoglobin
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
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