The relationship between methamphetamine usage and smoking in patients with psychotic disorders

Simple item page
dc.contributor.advisorTemmingh, Henk
dc.contributor.authorAdams, Ilhaam
dc.date.accessioned2025-10-31T06:49:29Z
dc.date.available2025-10-31T06:49:29Z
dc.date.issued2025
dc.date.updated2025-10-31T06:46:11Z
dc.description.abstractBackground: Methamphetamine and tobacco us are highly prevalent in psychotic disorders, however, the relationship between the dual use of these substances is poorly understood. Aim: To investigate the relationship between methamphetamine and tobacco use severity in patients with psychotic disorders and non-psychotic controls. Setting: Outpatients attending a specialist psychiatric hospital, Cape Town, South Africa. Methods: Participants (n=122) included those with schizophrenia (n=35), bipolar 1 disorder (n=29), methamphetamine-induced psychotic disorder(n=25), and non-psychotic controls (n=33). Diagnoses were determined using the Structured Clinical Interview (SCID-I) for the Diagnostic and Statistical Manual for Mental Disorders (DSM-IV-TR). Tobacco use was assessed with the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) tool. The association between methamphetamine use severity and smoking severity was modelled in a series of multivariable linear regression models. Results: Among the 122 participants, 31(25.4%) had used methamphetamine (mean SSI score =11.3, SD=10.1), whilst 68% (n=84) smoked tobacco, (mean SSI score=18, SD=9.7). A significant positive correlation was observed between methamphetamine and tobacco use (Spearman's Rho=0.47, p<0.001). After adjustment for education, diagnosis and other substances, patients with a high severity of methamphetamine use had significantly higher scores on the ASSIST scores for tobacco use compared to non-methamphetamine users (β 11.9; 95% CI 1.8 – 22.1; p=0.021). Conclusion: A strong correlation exists between severe methamphetamine and nicotine use in those with psychotic disorders. Contribution: Patients with psychotic disorders should routinely be screened for both methamphetamine and nicotine use, given the risk of adverse health consequences linked to dual usage. This should inform future therapeutic interventions.
dc.identifier.apacitationAdams, I. (2025). <i>The relationship between methamphetamine usage and smoking in patients with psychotic disorders</i>. (). University of Cape Town ,Faculty of Health Sciences ,Department of Psychiatry and Mental Health. Retrieved from http://hdl.handle.net/11427/42069en_ZA
dc.identifier.chicagocitationAdams, Ilhaam. <i>"The relationship between methamphetamine usage and smoking in patients with psychotic disorders."</i> ., University of Cape Town ,Faculty of Health Sciences ,Department of Psychiatry and Mental Health, 2025. http://hdl.handle.net/11427/42069en_ZA
dc.identifier.citationAdams, I. 2025. The relationship between methamphetamine usage and smoking in patients with psychotic disorders. . University of Cape Town ,Faculty of Health Sciences ,Department of Psychiatry and Mental Health. http://hdl.handle.net/11427/42069en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Adams, Ilhaam AB - Background: Methamphetamine and tobacco us are highly prevalent in psychotic disorders, however, the relationship between the dual use of these substances is poorly understood. Aim: To investigate the relationship between methamphetamine and tobacco use severity in patients with psychotic disorders and non-psychotic controls. Setting: Outpatients attending a specialist psychiatric hospital, Cape Town, South Africa. Methods: Participants (n=122) included those with schizophrenia (n=35), bipolar 1 disorder (n=29), methamphetamine-induced psychotic disorder(n=25), and non-psychotic controls (n=33). Diagnoses were determined using the Structured Clinical Interview (SCID-I) for the Diagnostic and Statistical Manual for Mental Disorders (DSM-IV-TR). Tobacco use was assessed with the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) tool. The association between methamphetamine use severity and smoking severity was modelled in a series of multivariable linear regression models. Results: Among the 122 participants, 31(25.4%) had used methamphetamine (mean SSI score =11.3, SD=10.1), whilst 68% (n=84) smoked tobacco, (mean SSI score=18, SD=9.7). A significant positive correlation was observed between methamphetamine and tobacco use (Spearman's Rho=0.47, p<0.001). After adjustment for education, diagnosis and other substances, patients with a high severity of methamphetamine use had significantly higher scores on the ASSIST scores for tobacco use compared to non-methamphetamine users (β 11.9; 95% CI 1.8 – 22.1; p=0.021). Conclusion: A strong correlation exists between severe methamphetamine and nicotine use in those with psychotic disorders. Contribution: Patients with psychotic disorders should routinely be screened for both methamphetamine and nicotine use, given the risk of adverse health consequences linked to dual usage. This should inform future therapeutic interventions. DA - 2025 DB - OpenUCT DP - University of Cape Town KW - Nicotine KW - Methamphetamine KW - Psychosis KW - Psychotic disorder KW - Western-Cape LK - https://open.uct.ac.za PB - University of Cape Town PY - 2025 T1 - The relationship between methamphetamine usage and smoking in patients with psychotic disorders TI - The relationship between methamphetamine usage and smoking in patients with psychotic disorders UR - http://hdl.handle.net/11427/42069 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/42069
dc.identifier.vancouvercitationAdams I. The relationship between methamphetamine usage and smoking in patients with psychotic disorders. []. University of Cape Town ,Faculty of Health Sciences ,Department of Psychiatry and Mental Health, 2025 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/42069en_ZA
dc.language.isoen
dc.language.rfc3066eng
dc.publisher.departmentDepartment of Psychiatry and Mental Health
dc.publisher.facultyFaculty of Health Sciences
dc.publisher.institutionUniversity of Cape Town
dc.subjectNicotine
dc.subjectMethamphetamine
dc.subjectPsychosis
dc.subjectPsychotic disorder
dc.subjectWestern-Cape
dc.titleThe relationship between methamphetamine usage and smoking in patients with psychotic disorders
dc.typeThesis / Dissertation
dc.type.qualificationlevelMasters
dc.type.qualificationlevelMMed
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
thesis_hsf_2025_adams ilhaam.pdf
Size:
2.19 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.72 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Masters