A description of the characteristics at presentation of children diagnosed with Diabetes Mellitus from 2005-2009 at Red Cross War Memorial Children's Hospital

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dc.contributor.advisorCarrihill, Michelle Margareten_ZA
dc.contributor.authorBotes, Alida Mariaen_ZA
dc.date.accessioned2017-01-24T09:12:01Z
dc.date.available2017-01-24T09:12:01Z
dc.date.issued2016en_ZA
dc.description.abstractObjective: To document the demographics, the pattern of clinical and laboratory characteristics at the time of diagnoses for all the newly diagnosed diabetics younger than 14 years reviewed at the Diabetic clinic at the Red Cross War Memorial Children's Hospital (RCWMH) during 2005-2009. Method: A retrospective folder review was done of all the newly diagnosed diabetics younger than 14 years old at the age of diagnosis. 225 patients were included for analysis. Patients were grouped according to age into a young group (1 month to < 5 years old), a middle group (5years - < 9 years) and an older group (9years - <14 years). Neonates were excluded as well as children who became diabetic secondary to another condition. Results: 58% of the patients were female and most of the patients were diagnosed with type 1 diabetes (96%). The median age at diagnosis was 8.5 years with a mean HbA1c of 11, 3%. 68% of the patients were in the normal weight category while 8, 4% of the patients were obese. 148 (65%) of the 225 patients presented in diabetic ketoacidosis (DKA). Only one of the patients classified with type 2 diabetes presented in DKA. 51 (22,67%) of the patients were less than 4 years old at the time of diagnosis. 53% of the Caucasian children were less than 4 years old at diagnosis while most of the children in the black and coloured group were diagnosed after 10 years of age. A seasonal variation was seen especially in the young age group with 66% presenting in autumn or winter months. Conclusions: Almost a quarter of diabetic children presented before the age of 4 years. A large proportion of patients presented in diabetic ketoacidosis which can be life threatening. Due to lack of information at diagnosis, this could be under reported significantly and calls for increase awareness amongst physicians and parents to recognise symptoms earlier. Prospective studies on childhood diabetes in South Africa are needed as well as a registry for childhood diabetes.en_ZA
dc.identifier.apacitationBotes, A. M. (2016). <i>A description of the characteristics at presentation of children diagnosed with Diabetes Mellitus from 2005-2009 at Red Cross War Memorial Children's Hospital</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Department of Paediatrics and Child Health. Retrieved from http://hdl.handle.net/11427/22985en_ZA
dc.identifier.chicagocitationBotes, Alida Maria. <i>"A description of the characteristics at presentation of children diagnosed with Diabetes Mellitus from 2005-2009 at Red Cross War Memorial Children's Hospital."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Department of Paediatrics and Child Health, 2016. http://hdl.handle.net/11427/22985en_ZA
dc.identifier.citationBotes, A. 2016. A description of the characteristics at presentation of children diagnosed with Diabetes Mellitus from 2005-2009 at Red Cross War Memorial Children's Hospital. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Botes, Alida Maria AB - Objective: To document the demographics, the pattern of clinical and laboratory characteristics at the time of diagnoses for all the newly diagnosed diabetics younger than 14 years reviewed at the Diabetic clinic at the Red Cross War Memorial Children's Hospital (RCWMH) during 2005-2009. Method: A retrospective folder review was done of all the newly diagnosed diabetics younger than 14 years old at the age of diagnosis. 225 patients were included for analysis. Patients were grouped according to age into a young group (1 month to < 5 years old), a middle group (5years - < 9 years) and an older group (9years - <14 years). Neonates were excluded as well as children who became diabetic secondary to another condition. Results: 58% of the patients were female and most of the patients were diagnosed with type 1 diabetes (96%). The median age at diagnosis was 8.5 years with a mean HbA1c of 11, 3%. 68% of the patients were in the normal weight category while 8, 4% of the patients were obese. 148 (65%) of the 225 patients presented in diabetic ketoacidosis (DKA). Only one of the patients classified with type 2 diabetes presented in DKA. 51 (22,67%) of the patients were less than 4 years old at the time of diagnosis. 53% of the Caucasian children were less than 4 years old at diagnosis while most of the children in the black and coloured group were diagnosed after 10 years of age. A seasonal variation was seen especially in the young age group with 66% presenting in autumn or winter months. Conclusions: Almost a quarter of diabetic children presented before the age of 4 years. A large proportion of patients presented in diabetic ketoacidosis which can be life threatening. Due to lack of information at diagnosis, this could be under reported significantly and calls for increase awareness amongst physicians and parents to recognise symptoms earlier. Prospective studies on childhood diabetes in South Africa are needed as well as a registry for childhood diabetes. DA - 2016 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2016 T1 - A description of the characteristics at presentation of children diagnosed with Diabetes Mellitus from 2005-2009 at Red Cross War Memorial Children's Hospital TI - A description of the characteristics at presentation of children diagnosed with Diabetes Mellitus from 2005-2009 at Red Cross War Memorial Children's Hospital UR - http://hdl.handle.net/11427/22985 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/22985
dc.identifier.vancouvercitationBotes AM. A description of the characteristics at presentation of children diagnosed with Diabetes Mellitus from 2005-2009 at Red Cross War Memorial Children's Hospital. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Department of Paediatrics and Child Health, 2016 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/22985en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Paediatrics and Child Healthen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherPaediatricsen_ZA
dc.titleA description of the characteristics at presentation of children diagnosed with Diabetes Mellitus from 2005-2009 at Red Cross War Memorial Children's Hospitalen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMMeden_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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