Estimation of adult antiretroviral treatment coverage in South Africa

dc.contributor.authorAdam, Muhammad Aarif
dc.contributor.authorJohnson, Leigh F
dc.date.accessioned2017-03-23T07:35:14Z
dc.date.available2017-03-23T07:35:14Z
dc.date.issued2009
dc.date.updated2016-01-07T09:49:28Z
dc.description.abstractObjectives: To estimate the annual numbers of individuals receiving antiretroviral treatment in South Africa up to mid-2008, and the coverage of antiretroviral treatment in adults according to various definitions of need. Methods: Antiretroviral coverage is defined as the number of patients receiving antiretroviral treatment at a point in time, divided by the number needing treatment. Numbers of patients receiving antiretroviral treatment are estimated from public sector data and data provided by disease management programmes and NGO programmes. The unmet need for treatment in adults is estimated using a Markov model of HIV progression in adults, combined with estimates of annual new HIV infections from a national AIDS and demographic model. Results: By the middle of 2008, 547 000 adults and children were receiving antiretroviral treatment in South Africa, with the public health sector accounting for 78% of this total. Using the current Department of Health criteria for defining antiretroviral eligibility (CD4+ count <200/μl or WHO stage 4), antiretroviral coverage in adults was 38.4% in 2008, up from 4.9% in 2004. Coverage increases to 52.6% if eligibility is based on WHO stage 4 only, but reduces to 21.2% if the South African HIV Clinicians Society guidelines are used to define eligibility. Coverage in 2007 varied between provinces, from 14.6% in Free State to 58.3% in the Western Cape. Conclusions: Significant progress has been made in expanding access to antiretroviral treatment in South Africa since 2004, but there remains a substantial unmet need for treatment in adults.
dc.identifier.apacitationAdam, M. A., & Johnson, L. F. (2009). Estimation of adult antiretroviral treatment coverage in South Africa. <i>South African Medical Journal</i>, http://hdl.handle.net/11427/24079en_ZA
dc.identifier.chicagocitationAdam, Muhammad Aarif, and Leigh F Johnson "Estimation of adult antiretroviral treatment coverage in South Africa." <i>South African Medical Journal</i> (2009) http://hdl.handle.net/11427/24079en_ZA
dc.identifier.citationAdam, M., & Johnson, L. (2009). Estimation of adult antiretroviral treatment coverage in South Africa. South African Medical Journal, 99(9), 661.
dc.identifier.ris TY - Journal Article AU - Adam, Muhammad Aarif AU - Johnson, Leigh F AB - Objectives: To estimate the annual numbers of individuals receiving antiretroviral treatment in South Africa up to mid-2008, and the coverage of antiretroviral treatment in adults according to various definitions of need. Methods: Antiretroviral coverage is defined as the number of patients receiving antiretroviral treatment at a point in time, divided by the number needing treatment. Numbers of patients receiving antiretroviral treatment are estimated from public sector data and data provided by disease management programmes and NGO programmes. The unmet need for treatment in adults is estimated using a Markov model of HIV progression in adults, combined with estimates of annual new HIV infections from a national AIDS and demographic model. Results: By the middle of 2008, 547 000 adults and children were receiving antiretroviral treatment in South Africa, with the public health sector accounting for 78% of this total. Using the current Department of Health criteria for defining antiretroviral eligibility (CD4+ count <200/μl or WHO stage 4), antiretroviral coverage in adults was 38.4% in 2008, up from 4.9% in 2004. Coverage increases to 52.6% if eligibility is based on WHO stage 4 only, but reduces to 21.2% if the South African HIV Clinicians Society guidelines are used to define eligibility. Coverage in 2007 varied between provinces, from 14.6% in Free State to 58.3% in the Western Cape. Conclusions: Significant progress has been made in expanding access to antiretroviral treatment in South Africa since 2004, but there remains a substantial unmet need for treatment in adults. DA - 2009 DB - OpenUCT DO - 10.7196/SAMJ.3271 DP - University of Cape Town J1 - South African Medical Journal LK - https://open.uct.ac.za PB - University of Cape Town PY - 2009 T1 - Estimation of adult antiretroviral treatment coverage in South Africa TI - Estimation of adult antiretroviral treatment coverage in South Africa UR - http://hdl.handle.net/11427/24079 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/24079
dc.identifier.urihttp://dx.doi.org/10.7196/SAMJ.3271
dc.identifier.vancouvercitationAdam MA, Johnson LF. Estimation of adult antiretroviral treatment coverage in South Africa. South African Medical Journal. 2009; http://hdl.handle.net/11427/24079.en_ZA
dc.language.isoeng
dc.publisher.departmentCentre for Actuarial Research (CARE)en_ZA
dc.publisher.facultyFaculty of Commerceen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rightsThis article is protected by Creative Commons Attribution - NonCommercial Works License (CC BY-NC 4.0)
dc.rights.urihttps://creativecommons.org/licenses/by-nc/3.0/
dc.sourceSouth African Medical Journal
dc.source.urihttp://www.samj.org.za/index.php/samj
dc.titleEstimation of adult antiretroviral treatment coverage in South Africa
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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