Impact of childhood trauma on functionality and quality of life in HIV-infected women

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dc.contributor.authorTroeman, Zyrheaen_ZA
dc.contributor.authorSpies, Georginaen_ZA
dc.contributor.authorCherner, Marianaen_ZA
dc.contributor.authorArchibald, Sarahen_ZA
dc.contributor.authorFennema-Notestine, Christineen_ZA
dc.contributor.authorTheilmann, Rebeccaen_ZA
dc.contributor.authorSpottiswoode, Bruceen_ZA
dc.contributor.authorStein, Danen_ZA
dc.contributor.authorSeedat, Sorayaen_ZA
dc.date.accessioned2015-10-30T09:35:52Z
dc.date.available2015-10-30T09:35:52Z
dc.date.issued2011en_ZA
dc.description.abstractBACKGROUND:While there are many published studies on HIV and functional limitations, there are few in the context of early abuse and its impact on functionality and Quality of Life (QoL) in HIV. METHODS: The present study focused on HIV in the context of childhood trauma and its impact on functionality and Quality of Life (QoL) by evaluating 85 HIV-positive (48 with childhood trauma and 37 without) and 52 HIV-negative (21 with childhood trauma and 31 without) South African women infected with Clade C HIV. QoL was assessed using the Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q), the Patient's Assessment of Own Functioning Inventory (PAOFI), the Activities of Daily Living (ADL) scale and the Sheehan Disability Scale (SDS). Furthermore, participants were assessed using the Center for Epidemiologic Studies Depression Scale (CES-D) and the Childhood Trauma Questionnaire (CTQ). RESULTS: Subjects had a mean age of 30.1 years. After controlling for age, level of education and CES-D scores, analysis of covariance (ANCOVA) demonstrated significant individual effects of HIV status and childhood trauma on self-reported QoL. No significant interactional effects were evident. Functional limitation was, however, negatively correlated with CD4 lymphocyte count. CONCLUSIONS: In assessing QoL in HIV-infected women, we were able to demonstrate the impact of childhood trauma on functional limitations in HIV.en_ZA
dc.identifier.apacitationTroeman, Z., Spies, G., Cherner, M., Archibald, S., Fennema-Notestine, C., Theilmann, R., ... Seedat, S. (2011). Impact of childhood trauma on functionality and quality of life in HIV-infected women. <i>Health and Quality of Life Outcomes</i>, http://hdl.handle.net/11427/14539en_ZA
dc.identifier.chicagocitationTroeman, Zyrhea, Georgina Spies, Mariana Cherner, Sarah Archibald, Christine Fennema-Notestine, Rebecca Theilmann, Bruce Spottiswoode, Dan Stein, and Soraya Seedat "Impact of childhood trauma on functionality and quality of life in HIV-infected women." <i>Health and Quality of Life Outcomes</i> (2011) http://hdl.handle.net/11427/14539en_ZA
dc.identifier.citationTroeman, Z. C., Spies, G., Cherner, M., Archibald, S. L., Fennema-Notestine, C., Theilmann, R. J., ... & Seedat, S. (2011). Impact of childhood trauma on functionality and quality of life in HIV-infected women. Health Qual Life Outcomes, 9, 84.en_ZA
dc.identifier.ris TY - Journal Article AU - Troeman, Zyrhea AU - Spies, Georgina AU - Cherner, Mariana AU - Archibald, Sarah AU - Fennema-Notestine, Christine AU - Theilmann, Rebecca AU - Spottiswoode, Bruce AU - Stein, Dan AU - Seedat, Soraya AB - BACKGROUND:While there are many published studies on HIV and functional limitations, there are few in the context of early abuse and its impact on functionality and Quality of Life (QoL) in HIV. METHODS: The present study focused on HIV in the context of childhood trauma and its impact on functionality and Quality of Life (QoL) by evaluating 85 HIV-positive (48 with childhood trauma and 37 without) and 52 HIV-negative (21 with childhood trauma and 31 without) South African women infected with Clade C HIV. QoL was assessed using the Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q), the Patient's Assessment of Own Functioning Inventory (PAOFI), the Activities of Daily Living (ADL) scale and the Sheehan Disability Scale (SDS). Furthermore, participants were assessed using the Center for Epidemiologic Studies Depression Scale (CES-D) and the Childhood Trauma Questionnaire (CTQ). RESULTS: Subjects had a mean age of 30.1 years. After controlling for age, level of education and CES-D scores, analysis of covariance (ANCOVA) demonstrated significant individual effects of HIV status and childhood trauma on self-reported QoL. No significant interactional effects were evident. Functional limitation was, however, negatively correlated with CD4 lymphocyte count. CONCLUSIONS: In assessing QoL in HIV-infected women, we were able to demonstrate the impact of childhood trauma on functional limitations in HIV. DA - 2011 DB - OpenUCT DO - 10.1186/1477-7525-9-84 DP - University of Cape Town J1 - Health and Quality of Life Outcomes LK - https://open.uct.ac.za PB - University of Cape Town PY - 2011 T1 - Impact of childhood trauma on functionality and quality of life in HIV-infected women TI - Impact of childhood trauma on functionality and quality of life in HIV-infected women UR - http://hdl.handle.net/11427/14539 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/14539
dc.identifier.urihttp://dx.doi.org/10.1186/1477-7525-9-84
dc.identifier.vancouvercitationTroeman Z, Spies G, Cherner M, Archibald S, Fennema-Notestine C, Theilmann R, et al. Impact of childhood trauma on functionality and quality of life in HIV-infected women. Health and Quality of Life Outcomes. 2011; http://hdl.handle.net/11427/14539.en_ZA
dc.language.isoengen_ZA
dc.publisherBioMed Central Ltden_ZA
dc.publisher.departmentDepartment of Psychiatry and Mental Healthen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution Licenseen_ZA
dc.rights.holder2011 Troeman et al; licensee BioMed Central Ltd.en_ZA
dc.rights.urihttp://creativecommons.org/licenses/by/2.0en_ZA
dc.sourceHealth and Quality of Life Outcomesen_ZA
dc.source.urihttp://hqlo.biomedcentral.com/en_ZA
dc.subject.otherHIVen_ZA
dc.subject.otherQuality of Lifeen_ZA
dc.subject.otherChildhood traumaen_ZA
dc.subject.otherFunctionalityen_ZA
dc.titleImpact of childhood trauma on functionality and quality of life in HIV-infected womenen_ZA
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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