Mobile phone text messaging for promoting adherence to anti-tuberculosis treatment: a systematic review protocol

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dc.contributor.authorNglazi, Mweeteen_ZA
dc.contributor.authorBekker, Linda-Gailen_ZA
dc.contributor.authorWood, Robinen_ZA
dc.contributor.authorHussey, Gregory Den_ZA
dc.contributor.authorWiysonge, Charles Sen_ZA
dc.date.accessioned2015-11-23T11:39:06Z
dc.date.available2015-11-23T11:39:06Z
dc.date.issued2013en_ZA
dc.description.abstractBACKGROUND: In 2010, there were approximately 8.8 million incident cases of tuberculosis (TB) worldwide. The treatment of TB is at least six months long and may be complicated by a high pill burden. In addition, TB patients often do not take their medication on schedule simply because they forget. Mobile phone text messaging has the potential to help promote TB treatment adherence. We, therefore, propose to conduct a review of current best evidence for the use of mobile phone text messaging to promote patient adherence to TB treatment. METHODS: This is a systematic review of the literature. We will preferably include randomized controlled trials (RCTs). However, non-randomized studies (NRS) will be considered if there is an inadequate number of RCTs.We will search PubMed, EMBASE, CINAHL, CENTRAL, Science Citation Index, Africa-Wide Information, and WHOLIS electronic databases for eligible studies available by 30 November 2012 regardless of language or publication status. We will also check reference lists for additional studies, identify abstracts from conference proceedings and communicate with authors for any relevant material.At least two authors will independently screen search outputs, select studies, extract data and assess the risk of bias (using separate criteria for RCTs and NRS); resolving discrepancies by discussion and consensus. We will assess clinical heterogeneity by examining the types of participants, interventions and outcomes in each study and pool studies judged to be clinically homogenous. We will also assess statistical heterogeneity using the chi-square test of homogeneity and quantify it using the I-square statistic. If study results are found to be statistically homogeneous (that is heterogeneity P > 0.1), we will pool them using the fixed-effect meta-analysis. Otherwise, we will use random-effects meta-analysis. We will calculate risk ratios and their corresponding 95% confidence intervals for dichotomous outcomes, and mean differences for continuous outcomes. For other outcomes without quantitative data, a descriptive analysis will be used.DISCUSSION:Our results can be used by researchers and policy-makers to help inform them of the efficacy of mobile phone text messaging interventions to promote patient adherence to TB treatment.en_ZA
dc.identifier.apacitationNglazi, M., Bekker, L., Wood, R., Hussey, G. D., & Wiysonge, C. S. (2013). Mobile phone text messaging for promoting adherence to anti-tuberculosis treatment: a systematic review protocol. <i>Systematic Reviews</i>, http://hdl.handle.net/11427/15225en_ZA
dc.identifier.chicagocitationNglazi, Mweete, Linda-Gail Bekker, Robin Wood, Gregory D Hussey, and Charles S Wiysonge "Mobile phone text messaging for promoting adherence to anti-tuberculosis treatment: a systematic review protocol." <i>Systematic Reviews</i> (2013) http://hdl.handle.net/11427/15225en_ZA
dc.identifier.citationglazi, M. D., Bekker, L. G., Wood, R., Hussey, G. D., & Wiysonge, C. S. (2013). Mobile phone text messaging for promoting adherence to anti-tuberculosis treatment: a systematic review protocol. Syst Rev, 2(6), 21.en_ZA
dc.identifier.ris TY - Journal Article AU - Nglazi, Mweete AU - Bekker, Linda-Gail AU - Wood, Robin AU - Hussey, Gregory D AU - Wiysonge, Charles S AB - BACKGROUND: In 2010, there were approximately 8.8 million incident cases of tuberculosis (TB) worldwide. The treatment of TB is at least six months long and may be complicated by a high pill burden. In addition, TB patients often do not take their medication on schedule simply because they forget. Mobile phone text messaging has the potential to help promote TB treatment adherence. We, therefore, propose to conduct a review of current best evidence for the use of mobile phone text messaging to promote patient adherence to TB treatment. METHODS: This is a systematic review of the literature. We will preferably include randomized controlled trials (RCTs). However, non-randomized studies (NRS) will be considered if there is an inadequate number of RCTs.We will search PubMed, EMBASE, CINAHL, CENTRAL, Science Citation Index, Africa-Wide Information, and WHOLIS electronic databases for eligible studies available by 30 November 2012 regardless of language or publication status. We will also check reference lists for additional studies, identify abstracts from conference proceedings and communicate with authors for any relevant material.At least two authors will independently screen search outputs, select studies, extract data and assess the risk of bias (using separate criteria for RCTs and NRS); resolving discrepancies by discussion and consensus. We will assess clinical heterogeneity by examining the types of participants, interventions and outcomes in each study and pool studies judged to be clinically homogenous. We will also assess statistical heterogeneity using the chi-square test of homogeneity and quantify it using the I-square statistic. If study results are found to be statistically homogeneous (that is heterogeneity P > 0.1), we will pool them using the fixed-effect meta-analysis. Otherwise, we will use random-effects meta-analysis. We will calculate risk ratios and their corresponding 95% confidence intervals for dichotomous outcomes, and mean differences for continuous outcomes. For other outcomes without quantitative data, a descriptive analysis will be used.DISCUSSION:Our results can be used by researchers and policy-makers to help inform them of the efficacy of mobile phone text messaging interventions to promote patient adherence to TB treatment. DA - 2013 DB - OpenUCT DO - 10.1186/2046-4053-2-6 DP - University of Cape Town J1 - Systematic Reviews LK - https://open.uct.ac.za PB - University of Cape Town PY - 2013 T1 - Mobile phone text messaging for promoting adherence to anti-tuberculosis treatment: a systematic review protocol TI - Mobile phone text messaging for promoting adherence to anti-tuberculosis treatment: a systematic review protocol UR - http://hdl.handle.net/11427/15225 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/15225
dc.identifier.urihttp://dx.doi.org/10.1186/2046-4053-2-6
dc.identifier.vancouvercitationNglazi M, Bekker L, Wood R, Hussey GD, Wiysonge CS. Mobile phone text messaging for promoting adherence to anti-tuberculosis treatment: a systematic review protocol. Systematic Reviews. 2013; http://hdl.handle.net/11427/15225.en_ZA
dc.language.isoengen_ZA
dc.publisherBioMed Central Ltden_ZA
dc.publisher.departmentDesmond Tutu HIV Centreen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution Licenseen_ZA
dc.rights.holder2013 Nglazi et al.; licensee BioMed Central Ltd.en_ZA
dc.rights.urihttp://creativecommons.org/licenses/by/2.0en_ZA
dc.sourceSystematic Reviewsen_ZA
dc.source.urihttp://www.systematicreviewsjournal.com/en_ZA
dc.subject.otherMobile phoneen_ZA
dc.subject.otherText messagesen_ZA
dc.subject.otherTuberculosis treatmenten_ZA
dc.subject.otherAnti-tubercular agentsen_ZA
dc.subject.otherAdherenceen_ZA
dc.subject.otherComplianceen_ZA
dc.titleMobile phone text messaging for promoting adherence to anti-tuberculosis treatment: a systematic review protocolen_ZA
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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