Using GRADE methodology for the development of public health guidelines for the prevention and treatment of HIV and other STIs among men who have sex with men and transgender people

Simple item page
dc.contributor.authorAkl, Elie A
dc.contributor.authorKennedy, Caitlin
dc.contributor.authorKonda, Kelika
dc.contributor.authorCaceres, Carlos F
dc.contributor.authorHorvath, Tara
dc.contributor.authorAyala, George
dc.contributor.authorDoupe, Andrew
dc.contributor.authorGerbase, Antonio
dc.contributor.authorWiysonge, Charles Shey
dc.contributor.authorSegura, Eddy R
dc.contributor.authorSchYnemann, Holger J
dc.contributor.authorLo, Ying-Ru
dc.date.accessioned2021-10-08T06:54:48Z
dc.date.available2021-10-08T06:54:48Z
dc.date.issued2012
dc.description.abstractBackgroundThe World Health Organization (WHO) Department of HIV/AIDS led the development of public health guidelines for delivering an evidence-based, essential package of interventions for the prevention and treatment of HIV and other sexually transmitted infections (STIs) among men who have sex with men (MSM) and transgender people in the health sector in low- and middle-income countries. The objective of this paper is to review the methodological challenges faced and solutions applied during the development of the guidelines.MethodsThe development of the guidelines followed the WHO guideline development process, which utilizes the GRADE approach. We identified, categorized and labeled the challenges identified in the guidelines development process and described the solutions through an interactive process of in-person and electronic communication.ResultsWe describe how we dealt with the following challenges: (1) heterogeneous and complex interventions; (2) paucity of trial data; (3) selecting outcomes of interest; (4) using indirect evidence; (5) integrating values and preferences; (6) considering resource use; (7) addressing social and legal barriers; (8) wording of recommendations; and (9) developing global guidelines.ConclusionWe were able to successfully apply the GRADE approach for developing recommendations for public health interventions. Applying the general principles of the approach while carefully considering specific challenges can enhance both the process and the outcome of guideline development.
dc.identifier.apacitationAkl, E. A., Kennedy, C., Konda, K., Caceres, C. F., Horvath, T., Ayala, G., ... Lo, Y. (2012). Using GRADE methodology for the development of public health guidelines for the prevention and treatment of HIV and other STIs among men who have sex with men and transgender people. <i>BMC Public Health</i>, 12(1), 174 - 177. http://hdl.handle.net/11427/34342en_ZA
dc.identifier.chicagocitationAkl, Elie A, Caitlin Kennedy, Kelika Konda, Carlos F Caceres, Tara Horvath, George Ayala, Andrew Doupe, et al "Using GRADE methodology for the development of public health guidelines for the prevention and treatment of HIV and other STIs among men who have sex with men and transgender people." <i>BMC Public Health</i> 12, 1. (2012): 174 - 177. http://hdl.handle.net/11427/34342en_ZA
dc.identifier.citationAkl, E.A., Kennedy, C., Konda, K., Caceres, C.F., Horvath, T., Ayala, G., Doupe, A. & Gerbase, A. et al. 2012. Using GRADE methodology for the development of public health guidelines for the prevention and treatment of HIV and other STIs among men who have sex with men and transgender people. <i>BMC Public Health.</i> 12(1):174 - 177. http://hdl.handle.net/11427/34342en_ZA
dc.identifier.issn1471-2458
dc.identifier.ris TY - Journal Article AU - Akl, Elie A AU - Kennedy, Caitlin AU - Konda, Kelika AU - Caceres, Carlos F AU - Horvath, Tara AU - Ayala, George AU - Doupe, Andrew AU - Gerbase, Antonio AU - Wiysonge, Charles Shey AU - Segura, Eddy R AU - SchYnemann, Holger J AU - Lo, Ying-Ru AB - BackgroundThe World Health Organization (WHO) Department of HIV/AIDS led the development of public health guidelines for delivering an evidence-based, essential package of interventions for the prevention and treatment of HIV and other sexually transmitted infections (STIs) among men who have sex with men (MSM) and transgender people in the health sector in low- and middle-income countries. The objective of this paper is to review the methodological challenges faced and solutions applied during the development of the guidelines.MethodsThe development of the guidelines followed the WHO guideline development process, which utilizes the GRADE approach. We identified, categorized and labeled the challenges identified in the guidelines development process and described the solutions through an interactive process of in-person and electronic communication.ResultsWe describe how we dealt with the following challenges: (1) heterogeneous and complex interventions; (2) paucity of trial data; (3) selecting outcomes of interest; (4) using indirect evidence; (5) integrating values and preferences; (6) considering resource use; (7) addressing social and legal barriers; (8) wording of recommendations; and (9) developing global guidelines.ConclusionWe were able to successfully apply the GRADE approach for developing recommendations for public health interventions. Applying the general principles of the approach while carefully considering specific challenges can enhance both the process and the outcome of guideline development. DA - 2012 DB - OpenUCT DP - University of Cape Town IS - 1 J1 - BMC Public Health LK - https://open.uct.ac.za PY - 2012 SM - 1471-2458 T1 - Using GRADE methodology for the development of public health guidelines for the prevention and treatment of HIV and other STIs among men who have sex with men and transgender people TI - Using GRADE methodology for the development of public health guidelines for the prevention and treatment of HIV and other STIs among men who have sex with men and transgender people UR - http://hdl.handle.net/11427/34342 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/34342
dc.identifier.vancouvercitationAkl EA, Kennedy C, Konda K, Caceres CF, Horvath T, Ayala G, et al. Using GRADE methodology for the development of public health guidelines for the prevention and treatment of HIV and other STIs among men who have sex with men and transgender people. BMC Public Health. 2012;12(1):174 - 177. http://hdl.handle.net/11427/34342.en_ZA
dc.language.isoeng
dc.publisher.departmentDepartment of Medicine
dc.publisher.facultyFaculty of Health Sciences
dc.sourceBMC Public Health
dc.source.journalissue1
dc.source.journalvolume12
dc.source.pagination174 - 177
dc.source.urihttps://dx.doi.org/10.1186/1471-2458-12-386
dc.subject.otherDeveloping Countries
dc.subject.otherEvidence-Based Medicine
dc.subject.otherHIV Infections
dc.subject.otherHomosexuality, Male
dc.subject.otherHumans
dc.subject.otherMale
dc.subject.otherPractice Guidelines as Topic
dc.subject.otherSexually Transmitted Diseases
dc.subject.otherTransgender Persons
dc.subject.otherWorld Health Organization
dc.titleUsing GRADE methodology for the development of public health guidelines for the prevention and treatment of HIV and other STIs among men who have sex with men and transgender people
dc.typeJournal Article
uct.type.publicationResearch
uct.type.resourceJournal Article
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
AklElieA_Using_GRADE_met_2012.pdf
Size:
444.92 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Journal Articles