Elucidation of bipolar disorder : a convergent approach using genetics and imaging
Master Thesis
2011
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University of Cape Town
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The aims were to determine whether variants, within ten selected candidate genes, have an association with BPD and whether any relationship exists between these variants and brain imaging volumes in subjects with BPD. The objectives were to i) select a list of BPD candidate genes, ii) identify a cohort of individuals from the BPD registry, iii) genotype the candidate genes using a polymerase chain reaction (PCR) based technology, iv) analyse the genotyping data with the appropriate statistical methods, and v) obtain brain imaging data and perform the appropriate statistical analysis.
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Dalvie, S. 2011. Elucidation of bipolar disorder : a convergent approach using genetics and imaging. University of Cape Town.