Browsing by Subject "substance use"

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    Associations between ADHD symptoms and maternal and birth outcomes: An exploratory analysis in a multi-country cohort of expectant mothers
    (2022) Murray, Aja Louise; Taut, Diana; Baban, Adriana; Hemady, Chad Lance; Walker, Susan; Osafo, Joseph; Sikander, Siham; Tomlinson, Mark; Du Toit, Stefani; Marlow, Marguerite; Ward, Catherine L; Fernando, Asvini; Madrid, Bernadette; Thang, Vo Van; Tuyen, Hoang Dinh; Dunne, Michael; Hughes, Claire; Fearon, Pasco; Valdebenito, Sara
    ADHD symptoms can adversely impact functioning in a range of domains relevant for maternal well-being and foetal development; however, there has been almost no research examining their impact during pregnancy. We used data (n=1204) from a longitudinal birth cohort study spanning eight countries to address this gap. ADHD symptoms in the third trimester of pregnancy were associated with lower social support from family (b=-0.16, p=.031), friends (b=-0.16, p=.024), and significant others (b=-0.09 p=.001); higher stress (b=0.34, p<.001) and depressive symptoms (b=0.31, p<.001), and increased likelihood of an unwanted pregnancy (b=0.30, p=.009). Significant associations with tobacco use (b=.36, p=.023) and premature birth (b=.35, p=.007) did not survive correction for multiple comparisons and there were no significant associations with alcohol use, low birth weight, or unplanned pregnancy. Results suggest that women with ADHD symptoms could benefit from earlier, more regular screening for mental health difficulties and greater mental health support during pregnancy.
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    Risk factors for substance use in pregnant women in South Africa
    (2012) Vythilingum, Bavanisha; Roos, Annerine; Faure, Sheila C; Geerts, Lut; Stein, Dan J
    Objectives. To study the prevalence of alcohol and substance use in a South African antenatal population and its correlates with socio-demographic factors, depression and perceived stress. Methods. A prospective self-report study on all women presenting for their first antenatal visit who consented to the study at a midwife obstetric unit (MOU) in the East Metropole district, Cape Town, using the Alcohol Use Disorders Identification Test (AUDIT), Drug Use Disorders Identification Test (DUDIT), Edinburgh Depression Scale (EDS) and Perceived Stress Scale (PSS). Statistical analyses using the chi-square test, separate one-way analyses of variance (ANOVA) and logistic regression analyses were performed as appropriate. Outcome measures were depression, alcohol use and substance use. Results. The questionnaire was completed by 323 women. During pregnancy 36.8% of women smoked, 20.2% used alcohol and 4% used substances. Using EDS cut-off scores of 12 and 15, respectively, 48.9% and 33.6% of the sample had scores consistent with major depression. An EDS cut-off score of 12 was significantly associated with both alcohol use (25.9% v. 15.2%, p=0.019) and risky drinking (76.9% v. 36.8%, p=0.04), while an EDS cut-off score of 15 was significantly associated with substance use (8.2% v. 1.4%, p=0.004) as well as alcohol dependence (23.1% v. 3.1%). Conclusions. We found high rates of both alcohol abuse and antenatal depression, and a significant association between depression, substance use and alcohol abuse; EDS scores greater than 12 could be used to identify women at risk of alcohol dependence and/or substance abuse.