Browsing by Subject "infancy"

Now showing 1 - 3 of 3
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    Hyaline membrane disease: a study of lung function and treatment
    (1967) Harrison, V C
    At present, both the aetiology of hyaline membrane disease and a means of preventing it remain unknown. Recent studies indicate that a significant number of infants die of respiratory failure but there is no general agreement concerning the changes of pulmonary function which lead to this stage. Two approaches have been used in the treatment of respiratory decompensation. First it has been proposed that blood gas and acid base abnormalities which result from respiratory failure can be prevented by oxygen and intravenous alkali and secondly an attempt has been made to correct abnormal lung function itself by means of artificial ventilation. These methods are directed at different aspects of the problem and their efficacy is as yet not established. The application of artificial ventilation in particular must depend on the nature of any ventilation, diffusion or perfusion defect.
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    Potassium in young children
    (1972) Mann, M D; Hansen, John
    Potassium i.s one of the major constituents of the human body but its role in metabolism is not clearly defined. One reason for this is the predominant intracellular distribution of the ion and the attendant difficulties in the detection of deficiency states. Serum potassium levels are of little value as over 95% of the potassium in the body is intracellular. Balance studies and the analysis of biopsy material have been used. However, they are so time consuming that they are only of use in establishing the diagnosis retrospectively and give very little indication of the severity of the deficit. Exchangeable potassium measurements do give an indication of the severity of the deficit. However, they involve the administration of an isotope which is not always available because of its short half-life. The development of the whole body counter has overcome most of these problems.
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    The respiratory distress syndrome of the newborn : studies of blood gases and acid/base balance with the object of formulating principles of treatment
    (1962) Warley, Mogamat Arashat; Gairdner, M T
    Respiratory failure accounts for a large, if not the largest, percentage of deaths during the first 48 hours of life. During the last ten years a great deal of research has been devoted to this early respiratory failure. The syndrome has been known by different names at different times; hyaline membrane disease (because pulmonary hyaline membrane is a frequent autopsy finding), congestive pulmonary failure, vernix membrane disease, pulmonary syndrome, and more recently the respiratory distress syndrome. A vast literature on the subject has accumulated. Many new and interesting facts have come to light and although many new theories have been put forth to explain the syndrome, the cause is still unknown.