Browsing by Subject "Zimbabwe"
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- ItemOpen AccessA case study exploring an occupational perspective of social inclusion among young adults dually afflicted with substance use disorder and HIV/AIDS in Zimbabwe(2021) Nhunzvi, Clement; Galvaan, Roshan; Langhaug, Lisa; Harding, RichardBackground: Curtailing adverse social determinants of health is pivotal to achieving the 2030 Agenda for Sustainable Development`s vision for a healthy and inclusive society. In Zimbabwe, fulfilling Vision 2030 may involve adopting socially inclusive approaches, particularly for young people dually afflicted with HIV and substance use disorders. However, social inclusion remains conceptually unclear and underutilized in relation to marginalized groups in low resource settings. This study sought to explore and understand how dually afflicted young adults with substance use disorders and HIV in Zimbabwe experienced and negotiated their social inclusion. Methods: This study utilised a qualitative instrumental case study design. Primary qualitative and quantitative data were collected to develop a thorough understanding of the case of an occupational perspective of social inclusion among dually afflicted young adults in Zimbabwe. The multiple methods used in this study included: i) narrative inquiry with five dually afflicted young adults; ii) in-depth interviews with five key informants; iii) document analysis of seven policies; and, iv) exploratory cross-sectional survey of social inclusion and associated factors (n=105). These multiple methods and sources contributed to the study`s trustworthiness. Multi-level case study analysis was applied as follows; 1st level: narrative analysis of each of the five young adults` stories, descriptive analysis of key informant interviews, document analysis and descriptive statistical analysis of the cross-sectional survey data. 2nd level: thematic case analysis drawing from all four data sources. 3rd level: theorised conceptual occupational constructs. Findings: Five narratives illustrated how using agency and having occupational choices were central to the young adults` experience and negotiation of social inclusion. The overarching Case theme was “Navigating an already troubled life: Striving for belonging and well-being”. This consists of three categories: 1) Dealing with a context of mixed realities, 2) Trying to adjust to new challenges and, 3) Life on the margins. These findings show how dually afflicted young adults in Zimbabwe respond and resist the influences of dominant discourses through dynamic and interconnected actions that shape their realities. Conclusion: The study describes and explains how dually afflicted young adults experienced and negotiated their social inclusion. The data affirms the role of agency and proposes a more critical view of occupational choice, activist occupational choice, in understanding social inclusion. As an emergent concept it is categorized by occupational choices, largely defying standard norms of engagement, and aims to break away from oppressive systems and problematic situations. Recognising the diverse manifestation of agency yields an appreciation for how occupations that are indigenous, collective, and resist oppression contributes to experiences of social inclusion.
- ItemOpen AccessA critical analysis of the doctrine of common purpose: special reference to South Africa, Zimbabwe, England and New South Wales(1996) Munangati, Nyaradzo Priscilla; Leeman, SollyThe aim of this paper is to examine the application of the doctrine of common purpose. The jurisdictions of South Africa, Zimbabwe, England and New South Wales have been chosen as points of reference, as the doctrine is still used by the prosecution in these jurisdictions in handling criminal matters where there is more than one defendant or accused person participating in the same unlawful enterprise. Most interesting is the fact that, these jurisdictions often refer to and rely on the decisions of each other, and sometimes even adopt the laws of the other jurisdiction to form part of the domestic law. This is apparent between South Africa and Zimbabwe; Zimbabwe and England; and England and New South Wales. Zimbabwe has shown a tendency to rely on South African law on common purpose as South Africa has managed to refine its laws on common purpose over the years. While South Africa would not hesitate to refer to Zimbabwean decisions as persuasive authority especially on the issue of dissociation, it is reluctant to refer directly to English law on dissociation. The irony however lies in the fact that, the Zimbabwean law on dissociation was in fact adopted from England without any changes at all and is in fact English law in all respects. This will become clear as one reads through this work. New South Wales law on. both common purpose and dissociation has been greatly influenced by English law, in fact, the law on dissociation is purely English law which was adopted. However, New South Wales stands out above the rest of the jurisdictions in so far as it distinguishes between "foundational crime" and "incidental crime" when dealing with offences perpetrated by parties to a common purpose. The whole legal scenario makes the examination of the application of the common purpose doctrine in the four jurisdictions not only interesting but exciting as well. It will be noted that in South Africa legal scholars have shown considerable zeal and interest in examining and dealing with issues pertaining to the application of the doctrine. Quite a number of articles by South African scholars are referred. to in this paper. Some of the articles were prompted by court decisions made in matters involving political unrest during the apartheid era, while others were written purely as a matter of scholarly academic interest. Unfortunately for Zimbabwe there are very, very few articles on the issue, and hence for the purpose of this paper there was heavy reliance on case law. As regards England and New South Wales, fairly recently published books were of invaluable assistance as they gave the most up to date information on how the doctrine of common purpose operates in England and in New South Wales. Case law was also heavily relied on. The paper not only relates how the doctrine has been perceived in each of the three jurisdictions but, there was also an attempt to display how the doctrine works, how issues of conduct and the mental element are dealt with,and finally any concerns which either the courts, the legal scholars or the writer find themselves confronted with.
- ItemOpen AccessA critical analysis of the doctrine of common purpose: special reference to South Africa, Zimbabwe, England and New South Wales(1996) Munangati, Nyaradzo Priscilla; Leeman, SollyThe aim of this paper is to examine the application of the doctrine of common purpose. The jurisdictions of South Africa, Zimbabwe, England and New South Wales have been chosen as points of reference, as the doctrine is still used by the prosecution in these jurisdictions in handling criminal matters where there is more than one defendant or accused person participating in the same unlawful enterprise. Most interesting is the fact that, these jurisdictions often refer to and rely on the decisions of each other, and sometimes even adopt the laws of the other jurisdiction to form part of the domestic law. This is apparent between South Africa and Zimbabwe; Zimbabwe and England; and England and New South Wales. Zimbabwe has shown a tendency to rely on South African law on common purpose as South Africa has managed to refine its laws on common purpose over the years. While South Africa would not hesitate to refer to Zimbabwean decisions as persuasive authority especially on the issue of dissociation, it is reluctant to refer directly to English law on dissociation. The irony however lies in the fact that, the Zimbabwean law on dissociation was in fact adopted from England without any changes at all and is in fact English law in all respects. This will become clear as one reads through this work. New South Wales law on. both common purpose and dissociation has been greatly influenced by English law, in fact, the law on dissociation is purely English law which was adopted. However, New South Wales stands out above the rest of the jurisdictions in so far as it distinguishes between "foundational crime" and "incidental crime" when dealing with offences perpetrated by parties to a common purpose. The whole legal scenario makes the examination of the application of the common purpose doctrine in the four jurisdictions not only interesting but exciting as well. It will be noted that in South Africa legal scholars have shown considerable zeal and interest in examining and dealing with issues pertaining to the application of the doctrine. Quite a number of articles by South African scholars are referred. to in this paper. Some of the articles were prompted by court decisions made in matters involving political unrest during the apartheid era, while others were written purely as a matter of scholarly academic interest. Unfortunately for Zimbabwe there are very, very few articles on the issue, and hence for the purpose of this paper there was heavy reliance on case law. As regards England and New South Wales, fairly recently published books were of invaluable assistance as they gave the most up to date information on how the doctrine of common purpose operates in England and in New South Wales. Case law was also heavily relied on. The paper not only relates how the doctrine has been perceived in each of the three jurisdictions but, there was also an attempt to display how the doctrine works, how issues of conduct and the mental element are dealt with,and finally any concerns which either the courts, the legal scholars or the writer find themselves confronted with.
- ItemOpen AccessA structural equation modelling of the buffering effect of social support on the report of common mental disorders in Zimbabwean women in the postnatal period(BioMed Central, 2019-02-28) Kaseke, Tanaka; January, James; Tadyanemhandu, Catherine; Chiwaridzo, Matthew; Dambi, Jermaine MObjective Globally, 13–20% of women experience a common mental disorder (CMD) postnatally. Unfortunately, the burden of CMDs is disproportionally substantial in women from low-income countries. Nevertheless, there is a growing recognition of the buffering effect of social support (SS) on psychiatric morbidity and the need for mental well-being support services/interventions. This study evaluated the relationship between psychiatric morbidity and SS levels, and factors influencing the mental health functioning of Zimbabwean women postnatally. Data were collected from 340 mothers and were analysed through structural equation modelling. Results The mothers’ mean age was 26.6 (SD 5.6) years. The mean Multidimensional Scale of Perceived Social Support score was 42.7 (SD 10.8), denoting high levels of SS. Additionally, 29.1% of the population reported excessive psychiatric morbidity, the median Shona Symptoms Questionnaire score was 5 (IQR: 2–8). The structural equation model demonstrated the buffering effects of SS on psychiatric morbidity (r = − 0.585, p = 0.01), and accounted for 70% of the variance. Being unmarried, increased maternal age, lower educational and income levels were associated with poorer maternal mental health. There is a need for routine; surveillance and treatment of CMDs in women in the postnatal period, including integration of low-cost, evidenced-based and task-shifting SS interventions.
- ItemOpen AccessAn analysis of how Zimbabwe’s international legal obligation to achieve the realisation of the right of access to adequate housing, can be enforced in domestic courts as a constitutional right, notwithstanding the absence of a specific constitutional right of every person to have access to adequate housing(2018) Mavedzenge, Justice Alfred; de Vos, Pierre; Corder, HughThe Constitution of Zimbabwe of 2013 does not expressly guarantee every person a right to have access to adequate housing. However, the Government of Zimbabwe has an international legal obligation to achieve the progressive realisation of the right to have access to adequate housing by everyone in the country. This obligation is derived from art 11 (1) of the International Covenant on Economic, Social and Cultural Rights (ICESCR). Zimbabwe is a dualist state and therefore, this obligation is not directly or automatically enforceable as municipal law in Zimbabwe. It can be enforced in domestic courts only if it has been enacted into legislation or if it is entrenched as a constitutional obligation. The absence of a specific constitutional right, guaranteed for everyone to have access to adequate housing, thus raises the concern that the government may not be held accountable, in the domestic courts, to comply with its international legal obligation to ensure that everyone enjoys access to adequate housing. There is a national housing crisis in Zimbabwe that is characterised by an acute shortage of adequate housing, mass forced evictions and unfair discrimination in the allocation of housing facilities by government. There is therefore an existing need to compel government to comply with and fulfil its international legal obligations relating to the right of every person to have access to adequate housing. In the absence of an explicit constitutional guarantee of such a right, it is necessary to find alternative constitutional rights which citizens and individuals in Zimbabwe can rely on to compel Government to comply with and fulfil its international legal obligations that arise from art 11 (1) of the ICESCR. The Constitution of Zimbabwe expressly guarantees for everyone the following rights; the fundamental freedom from arbitrary evictions, the right to life, the right to equality and the children’s right to shelter. The scope of each of these rights can be interpreted broadly to include some of the duties that ordinarily arise from the right to have access to adequate housing. Therefore, these rights can be applied together to enforce the international legal duty of the state to ensure the progressive realisation of the right to have access to adequate housing by everyone in Zimbabwe.
- ItemOpen AccessAn investigation into the progression of premarital fertility since the onset of Zimbabwe's fertility transition(2021) Ngwenya, Chantelle Linda; Moultrie, ThomasPremarital fertility, that is, childbearing before first marriage, is an important yet under researched demographic topic in sub-Saharan Africa. In Zimbabwe, the distinction by marital status in fertility research is hardly drawn. Hence, a gap exists in the knowledge of premarital fertility levels. This research aims to investigate levels of, and factors associated with, premarital fertility since the onset of Zimbabwe's fertility transition in the mid-1980s. The research employed direct fertility estimation techniques to effectively compare premarital, marital, and overall fertility trends between 1988 and 2015. Cox proportional-hazards regression and forest plot analyses were then used to explain changes in factors associated with the timing of premarital first births over the same period. Data quality assessments were carried out using the method of cohortperiod fertility rates to provide explanations for any erratic results. The results showed that premarital fertility was constant and moderate, with an average of 0.7 children per woman, between 1988 and 2015. While most premarital first births consistently occurred to younger women, from 2005 onwards, they increased among women aged above 24 years and decreased among adolescents. An increase in age, commencing sexual activity after adolescence, and improved socio-economic status including level of education decreased the relative risk of having a premarital first birth. However, delaying marriage past young womanhood, history of contraceptive use, Ndebele ethnicity, and residence in regions other than Manicaland and Masvingo, especially Ndebele dominated regions, increased the same risk by 465.0%, 45.5%, 136.0% and up to 135.0% respectively. The stagnation of premarital fertility between 1988 and 2015 while both marital and overall fertility first declined and then stalled indicates that there is insufficient evidence to suggest that premarital fertility had contributed to the stall of fertility decline in Zimbabwe from the mid-1990s. The timing of premarital first births since the start of the fertility transition in the 1980s has had a strong ethnic and cultural bias. Due to evidence of the effect of migrancy and tourism on premarital fertility in border and tourism towns, an extension into the theory of migrant premarital sexual behaviour to detail the risk of premarital fertility among border town residents who interact with but are neither migrants nor tourists is recommended.
- ItemOpen AccessAnalysis of virulence factors and antibiotic resistance genes in group B streptococcus from clinical samples(2021-01-28) Mudzana, Raymond; Mavenyengwa, Rooyen T; Gudza-Mugabe, MuchanetaBackground Streptococcus agalacticae (Group B Streptococcus, GBS) is one of the most important causative agents of serious infections among neonates. This study was carried out to identify antibiotic resistance and virulence genes associated with GBS isolated from pregnant women. Methods A total of 43 GBS isolates were obtained from 420 vaginal samples collected from HIV positive and negative women who were 13–35 weeks pregnant attending Antenatal Care at Chitungwiza and Harare Central Hospitals in Zimbabwe. Identification tests of GBS isolates was done using standard bacteriological methods and molecular identification testing. Antibiotic susceptibility testing was done using the modified Kirby-Bauer method and E-test strips. The boiling method was used to extract DNA and Polymerase Chain Reaction (PCR) was used to screen for 13 genes. Data was fed into SPSS 24.0. Results Nine distinct virulence gene profiles were identified and hly-scpB-bca-rib 37.2% (16/43) was common. The virulence genes identified were namely hly 97.8% (42/43), scpB 90.1% (39/43), bca 86.0% (37/43), rib 69.8% (30/43) and bac 11.6% (5/43). High resistance to tetracycline 97.7% (42/43) was reported followed by 72.1% (31/43) cefazolin, 69.8% (30/43) penicillin G, 58.1% (25/43) ampicillin, 55.8% (24/43) clindamycin, 46.5% (20/43) ceftriaxone, 34.9% (15/43) chloramphenicol, and 30.2% (13/43) for both erythromycin and vancomycin using disk diffusion. Antibiotic resistance genes among the resistant and intermediate-resistant isolates showed high frequencies for tetM 97.6% (41/42) and low frequencies for ermB 34.5% (10/29), ermTR 10.3% (3/29), mefA 3.4% (1/29), tetO 2.4% (1/42) and linB 0% (0/35). The atr housekeeping gene yielded 100% (43/43) positive results, whilst the mobile genetic element IS1548 yielded 9.3% (4/43). Conclusion The study showed high prevalence of hly, scpB, bca and rib virulence genes in S. agalactiae strains isolated from pregnant women. Tetracycline resistance was predominantly caused by the tetM gene, whilst macrolide resistance was predominantly due to the presence of erm methylase, with the ermB gene being more prevalent. Multi-drug resistance coupled with the recovery of resistant isolates to antimicrobial agents such as penicillins indicates the importance of GBS surveillance and susceptibility tests. It was also observed that in vitro phenotypic resistance is not always accurately predicted by resistance genotypes.
- ItemMetadata onlyAnalyzing Thabo Mbeki's policy of 'quiet diplomacy' in the Zimbabwean crisis(2010) Malimela, Langelihle Phakama; Akokpari, JohnThis thesis discusses the approach taken by the South African government in response to the political and economic crisis that has gripped neighbouring Zimbabwe since the year 2000. Its aim is to explain why South Africa, under the leadership of Thabo Mbeki, adopted the controversial policy widely referred to as 'Quiet Diplomacy'. It uses a Structuralist approach to international relations, and in particular Immanuel Wallerstein's World Systems Theory to characterise South Africa as a prototypical semi-peripheral state, with a dual-contradictory role in international relations. It argues that post- apartheid South Africa's failure to make genuine progress in terms primarily of economic transformation at home, has significantly constrained her ability to adopt more conventional diplomatic methods in dealing with the political and economic crisis in Zimbabwe.
- ItemOpen AccessAntiretroviral therapy outcomes among adolescents and youth in rural Zimbabwe(Public Library of Science, 2012) Bygrave, Helen; Mtangirwa, Judith; Ncube, Kwenzakwenkosi; Ford, Nathan; Kranzer, Katharina; Munyaradzi, DhodhoAround 2 million adolescents and 3 million youth are estimated to be living with HIV worldwide. Antiretroviral outcomes for this group appear to be worse compared to adults. We report antiretroviral therapy outcomes from a rural setting in Zimbabwe among patients aged 10-30 years who were initiated on ART between 2005 and 2008. The cohort was stratified into four age groups: 10-15 (young adolescents) 15.1-19 years (adolescents), 19.1-24 years (young adults) and 24.1-29.9 years (older adults). Survival analysis was used to estimate rates of deaths and loss to follow-up stratified by age group. Endpoints were time from ART initiation to death or loss to follow-up. Follow-up of patients on continuous therapy was censored at date of transfer, or study end (31 December 2008). Sex-adjusted Cox proportional hazards models were used to estimate hazard ratios for different age groups. 898 patients were included in the analysis; median duration on ART was 468 days. The risk of death were highest in adults compared to young adolescents (aHR 2.25, 95%CI 1.17-4.35). Young adults and adolescents had a 2-3 times higher risk of loss to follow-up compared to young adolescents. When estimating the risk of attrition combining loss to follow-up and death, young adults had the highest risk (aHR 2.70, 95%CI 1.62-4.52). This study highlights the need for adapted adherence support and service delivery models for both adolescents and young adults.
- ItemOpen AccessCircumstantial social entrepreneurship: Exploring inclusive, social innovation in the transition from shadow to mainstream economic spaces. A case study of informal sector recycling activities in Bulawayo, Zimbabwe(2018) Ndlovu, Sinqobile Sichelesile; Nilsson, WarrenAs global solid waste management systems evolve to include wider elements of sustainability, developing countries are struggling with how best to work with a growing informal sector. This research seeks to investigate how developing country mainstream solid waste management systems can harness the opportunities presented through the informal recycling sector. This research explores the dialogue around „formalisation of the informal‟ and „integration of informal recycling sector into mainstream solid waste management systems‟, approaching this from an informal sector perspective. The research endeavours to offer insights to this discourse from an inclusive, social innovation approach. The research looks at what business models the informal recycling sector use as they adopt or adapt industrialised practices and how these harness inclusion and social innovation. The research area is Bulawayo, Zimbabwe with the informal recycling sector as case study. The main research question is “How can we harness inclusion and social innovation as the informal sector transitions into mainstream economic spaces?” The research employs an inductive qualitative approach through a rapid ethnography, focus group discussions and semi-structured key informant interviews. Key concepts explored in this research include „circumstantial social entrepreneurship‟, „generational informality‟, „value chain alliances‟, „public, private, community and informal sector partnerships (PPCIPs)‟ and „inclusive development as a pre-requisite to formalisation‟. By unpacking the business models employed by the informal recycling sector and how inclusive, social innovation opportunities inherent in these can be harnessed during the transition from shadow to mainstream economy spaces, this research intends to offer progressive approaches on how to unlock shared value during the graduation of the informal recycling sector from shadow to mainstream socio-economic spaces. Additionally, the outputs of this research aim to contribute to context-specific knowledge on types of non traditional social entrepreneurial activity within informal spaces and how these push boundaries of inclusive, social innovation.
- ItemOpen AccessCombined HIV Adolescent Prevention Study (CHAPS): comparison of HIV pre-exposure prophylaxis regimens for adolescents in sub-Saharan Africa—study protocol for a mixed-methods study including a randomised controlled trial(2020-10-30) Nash, S; Dietrich, J; Ssemata, A S; Herrera, C; O’Hagan, K; Else, L; Chiodi, F; Kelly, C; Shattock, R; Chirenje, M; Lebina, L; Khoo, S; Bekker, L-G; Weiss, H A; Gray, C; Stranix-Chibanda, L.; Kaleebu, P; Seeley, J; Martinson, N; Fox, JBackground HIV remains a major public health issue, especially in Eastern and Southern Africa. Pre-exposure prophylaxis is highly effective when adhered to, but its effectiveness is limited by cost, user acceptability and uptake. The cost of a non-inferiority phase III trial is likely to be prohibitive, and thus, it is essential to select the best possible drug, dose and schedule in advance. The aim of this study, the Combined HIV Adolescent PrEP and Prevention Study (CHAPS), is to investigate the drug, dose and schedule of pre-exposure prophylaxis (PrEP) required for the protection against HIV and the acceptability of PrEP amongst young people in sub-Saharan Africa, and hence to inform the choice of intervention for future phase III PrEP studies and to improve strategies for PrEP implementation. Methods We propose a mixed-methods study amongst young people aged 13–24 years. The first component consists of qualitative research to identify the barriers and motivators towards the uptake of PrEP amongst young people in South Africa, Uganda and Zimbabwe. The second component is a randomised clinical trial (ClinicalTrials.gov NCT03986970, June 2019) using a novel ex vivo HIV challenge method to investigate the optimal PrEP treatment (FTC-TDF vs FTC-TAF), dose and schedule. We will recruit 144 amongst HIV-negative uncircumcised men aged 13–24 years from voluntary male medical circumcision clinics in two sites (South Africa and Uganda) and randomise them into one of nine arms. One group will receive no PrEP prior to surgery; the other arms will receive either FTC-TDF or FTC-TAF, over 1 or 2 days, and with the final dose given either 6 or 20 h prior to surgery. We will conduct an ex vivo HIV challenge on their resected foreskin tissue. Discussion This study will provide both qualitative and quantitative results to help decide the optimum drug, dose and schedule for a future phase III trial of PrEP. The study will also provide crucial information on successful strategies for providing PrEP to young people in sub-Saharan Africa. Trial registration ClinicalTrials.gov NCT03986970 . Registered on 14 June 2019
- ItemOpen AccessCommon mental disorders and barriers to adherence to HIV medications among emerging adults living with HIV using healthcare services in Harare(2020) Saruchera, Emily Wendy; Schneider, Marguerite; Abas, Melanie; Madhombiro, MunyaradziBackground: Emerging adulthood (18 to 29 years old) is a critical age group in relation to the Human Immunodeficiency Virus (HIV) epidemic and to mental health. A major public health concern globally, in management of HIV, is that emerging adults have suboptimal antiretroviral therapy (ART) adherence, yet they are the largest group initiating ART. In addition, common mental disorders (CMDs), including depression and anxiety have their peak incidence during this period and they have been found to increase risk of non-adherence to ART. Those with CMDs may have different types of barriers than those without CMDs. Furthermore, those with CMDs might be more likely to have a greater number of barriers to adherence than those without because of the way symptoms of CMDs impact on memory, problem solving skills and concentration. Aims: The main aim of this study was to describe barriers to adherence to ART in emerging adults living with HIV with probable CMDs (i.e. depression and/or anxiety) and accessing HIV treatment at a government clinic in Harare, Zimbabwe, compared to emerging adults living with HIV without probable CMDs. The specific objectives were: a. to determine the prevalence of probable CMDs among emerging adults living with HIV, b. to describe the prevalence, severity and common barriers to ART adherence, measured using the 22-item Barriers to Adherence (BARTA scale) in emerging adults living with HIV with probable CMDs and to compare this with those without probable CMDs. Methods: A representative sample of 223 emerging adults aged 18 to 29 years were recruited in a crosssectional study using the random sampling technique. The Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7) and Barriers to Adherence Scale (BARTA scale) were used to assess probable depression, probable anxiety and barriers to adherence respectively. Data Analysis: Univariate Descriptive statistics were used to describe the socio-demographic, prevalence of probable CMDs, prevalence of barriers to adherence, overall median of total BARTA score (severity of barriers to ART adherence) for the whole sample and overall median number of barriers to ART adherence for the whole sample. Chi-square analyses were used to compare the prevalence of barriers (no barrier vs. at least one) between participants with and without probable CMDs. Non-parametric Wilcoxon rank-sum tests and Kruskal Wallis tests (for variables with more than two categories) were used to I. Compare the number of barriers to ART adherence between participants with and without a probable CMDs; II. Compare the severity of barriers to ART adherence between participants with and without probable CMDs, using overall scores on the BARTA scale III. Assess the relationship between demographic variables, HIV related variables, Substance Use Disorders (SUD) and total BARTA scores. Variables which were significantly associated with BARTA scores were entered into a negative binomial regression model, to assess the relationship between CMDs and severity of barriers to ART adherence, this time controlling for possible demographic confounding factors. Results: The prevalence of probable CMDs (i.e. probable depression and/or probable anxiety) was 33.2%. Specifically, 31.8% had probable depression and 16.1% had probable anxiety. Results: showed that 76.2 % of the sample experienced at least one barrier to ART adherence and that 94.5% of those with CMDs experienced at least one barrier to adherence compared to 67.1% of those without CMDs (p>0.001). We found a significant difference (U=-7.209, p<0.001) between the number of barriers experienced by participants with and without CMDs: participants with a CMD reported a greater number of barriers (median (md) =5, IQR=3-7) compared to those without CMDs (md= 1, IQR=0-4). A statistically significant difference was also found in total BARTA scores between participants with and without CMDs: participants with a CMD reported a greater BARTA score (md=7, IQR=4-12) compared to those without a CMD (md= 2, IQR=0-4; U=-7.415, p<0.001). The most frequent barriers reported by emerging adults living with HIV with probable CMDs were 'forgetting' (68.0%), 'thinking too much' (49.0%), 'having to take ART in front of others' (41.0%) and 'not having a reminder' (39.0%). The most frequent barriers for emerging adults living with HIV without probable CMDs were 'forgetting' (30%), 'not having medications with them' (21%), 'not wanting others to know their status' (20%) and 'not having a reminder' (19%). Although 'forgetting' and 'not having a reminder' were among the top barriers in both groups, those with probable CMDs reported them more frequently. Conclusion: This study has shown that firstly, CMDs and barriers to ART adherence are prevalent among emerging adults living with HIV. Secondly, emerging adults living with HIV with probable CMDs experience a high number of barriers to ART adherence and more severely than those without probable CMDs. Finally, emerging adults with CMDs reported barriers such as forgetting and not having a reminder more frequently than those without CMDs. This calls for routine screening for probable CMDs and barriers to ART adherence in HIV clinics. Furthermore, there is need to come up with tailored psychological interventions that can simultaneously treat CMDs and reduce barriers to ART adherence among emerging adults living with HIV.
- ItemOpen AccessComparative performance characteristics of the urine lipoarabinomannan strip test and sputum smear microscopy in hospitalized HIV-infected patients with suspected tuberculosis in Harare, Zimbabwe(2015) Zijenah, Lynn Sodai; Kadzirange, Gerard; Bandason, Tsitsi; Chipiti, Maria Mary; Gwambiwa, Bevel; Makoga, Forget; Chungu, Pauline; Kaguru, Philip; Sabur, Natasha FBackgroundIn Zimbabwe, sputum smear microscopy (SSM) is the routinely used TB diagnostic tool in hospitalised HIV-infected patients. However, SSM has poor sensitivity in HIV-infected patients. We compared performance of urine lipoarabinomannan strip test (LAM) and SSM among hospitalized HIV-infected patients with suspected TB.MethodsHospitalized HIV-infected patients with suspected TB were randomized to LAM plus SSM or SSM alone groups as part of a larger multi-country parent study. Here we present a comparison of LAM versus SSM performance from the Zimbabwe study site. LAM analyses (grade 2 cut-off) were conducted using (i) a microbiological reference standard (MRS; culture positivity for M.tb and designated definite TB) and (ii) a composite reference standard (CRS; definite TB plus probable TB i.e. patients with clinical TB excluded from the culture negative group). CRS constituted the primary analysis.Results82/457 (18%) of the patients randomized to the LAM group were M.tuberculosis culture positive. Using CRS, sensitivity (%, 95 % CI) of LAM was significantly higher than SSM [49.2 (42.1-56.4) versus 29.4(23.2-36.3); p < 0.001]. Specificity and PPV were 98.1%, and 95.8%, respectively. By contrast, using MRS, LAM sensitivity was similar to SSM and specificity was significantly lower, however, the combined sensitivity of LAM and SSM was significantly higher than that of SSM alone, p = 0.009. Using CRS, LAM sensitivity (%, CI) was CD4 count dependent [60.6(50.7-69.8) at ≤50 cells/μL; 40.0(22.7-59.4) at 51-100 cells/μL, and 32.8(21.0-46.3) at >100 cells/μL. The combined sensitivity of LAM and SSM was higher than SSM alone being highest at CD4 counts <50 cells/μL [67.6(57.9-76.3); p = <0.001]. Specificity of LAM or SSM alone, or of combined LAM and SSM was >97% in all the 3 CD4 strata.ConclusionAmong hospitalized HIV-infected patients with suspected TB, the sensitivity of LAM is significantly higher than that of SSM, especially at low CD4 counts. LAM and SSM are complimentary tests for diagnosis of TB in HIV-infected patients. We recommend a combination of LAM and SSM for TB diagnosis in HIV-infected patients with low CD4 counts in HIV/TB co-endemic countries, where alternative methods are unavailable.
- ItemOpen AccessContent validity and test-retest reliability of a low back pain questionnaire in Zimbabwean adolescents(BioMed Central, 2017-02-28) Chiwaridzo, Matthew; Chikasha, Tafadzwa Nicole; Naidoo, Nirmala; Dambi, Jermaine Matewu; Tadyanemhandu, Cathrine; Munambah, Nyaradzai; Chizanga, Precious TrishBackground: In Zimbabwe, a recent increase in the volume of research on recurrent non-specific low back pain (NSLBP) has revealed that adolescents are commonly affected. This is alarming to health professionals and parents and calls for serious primary preventative strategies to be developed and implemented forthwith. Early identification initiatives should be prioritised in order to curtail the condition and its progression. In an attempt to be proactive in minimising the prevalence of recurrent NSLBP, this study was conducted to evaluate the content validity and test-retest reliability of a survey questionnaire with the aim of proffering a valid and reliable questionnaire which can be used in non-clinical settings to identify adolescents with recurrent NSLBP in Harare, Zimbabwe and determine the possible factors associated with the condition. Methods: The study was conducted in two parts. The first part assessed content validity of the questionnaire using four experts derived from academia and clinical practice. The second part evaluated the reliability of the questionnaire among 125 high school-children aged between 13 and 19 years in a test-retest study. Results: Twenty-six (26) out of thirty questions in the questionnaire had an Item Content Validity index of 1.00, demonstrating complete agreement among content experts. Overall, the Scale Content Validity Index for the questionnaire was 0.97. Item completion for the reliability study was satisfactory. The questionnaire items had kappa values ranging from 0.17 (slight agreement) to 1 (perfect agreement). High levels of reliability were found for the questions on school bag use (k=0.94), sports participation (k=0.97), and lifetime prevalence (k=0.89). Conclusion: Excellent content validity and slight to perfect test-retest reliability was found for the Low Back Pain (LBP) questionnaire. These results are comparable to findings of other studies evaluating the psychometric properties of LBP questionnaires. Cognisant of the limitations of the study, the results of this study suggest that the LBP questionnaire could be used in local studies investigating LBP among adolescents although questions enquiring on functional limitations and sciatica may need further consideration.
- ItemOpen AccessCorrelates of social support on report of probable common mental disorders in Zimbabwean informal caregivers of patients with stroke: a cross-sectional survey(2019-08-16) Marima, Phillipa; Gunduza, Ropafadzo; Machando, Debra; Dambi, Jermaine MAbstract Objective Stroke is a major global public health burden. Unfortunately, stroke invariably leads to functional limitations, consequently, most stroke survivors are hugely dependent on family members/informal caregivers in carrying out essential daily activities. The increased demands of caregiving negatively impact caregivers’ mental health. Nevertheless, caregivers who receive an adequate amount of social support are likely to adjust better to the caregiving role. We sought to determine the impact of social support on the mental wellbeing of 71 caregivers of patients with stroke in Zimbabwe, a low-resourced country. Results The mean caregiver age was 41.5 (SD 13.8) years. Patients had a mean age of 65.2 (SD 15.3) years with most being functionally dependent (93.2%). 45.1% of the caregivers showed excessive psychiatric morbidity. The mean Multidimensional Scale of Perceived Social Support (MSPSS) score was 44 (SD 9.4), denoting high levels of social support. Caregivers who received an adequate amount of social support were likely to report of lower psychiatric morbidity (Rho = − 0.285, p = 0.016). Furthermore, caregiver who were; poorer, were caring for more functionally-dependent patients, and did not receive additional assistance were likely to report of poor mental health functioning. There is therefore a strong need to implement context-specific caregivers wellness programs.
- ItemOpen AccessDesigning a dynamic spectrum sharing algorithm between DCS and LTE in the 1800 MHz band: a case study of a mobile telecommunication operator in Zimbabwe(2025) Magwa, Luckmore; Winberg, SimonIn recent years, there has been remarkable growth in the wireless devices and networks market, leading to the proliferation of numerous wireless services and applications. Consequently, regulatory agencies around the world have allocated licensed spectrum chunks to different wireless services to meet the increasing demand. Despite technological advancements such as Multiple Input Multiple Output (MIMO) communications, heterogeneous networks, and cooperative communications, spectrum scarcity continues to pose a challenge for regulatory agencies worldwide. Facing this challenge, Dynamic Spectrum Sharing (DSS) has emerged as a promising remedy. As a facet of frequency spectrum management, DSS aims to bolster spectrum utilization efficiency and elevate the end-user experience by introducing greater flexibility in the usage of spectrum resources. This Dissertation has substantiated DSS as a viable solution to the challenge of spectrum scarcity. It assessed the effectiveness and suitability of dynamic spectrum sharing within a conventional mobile network setting, concentrating on intra-operator scenarios encompassing Digital Cellular System (DCS), also recognized as GSM1800, and LTE radio technologies. Monte Carlo-style system-level simulations were conducted using Atoll, utilizing raster traffic maps provided by the Mobile Network Operator (MNO). These simulations served two main purposes: firstly, to benchmark the simulator's performance with actual network performance data collected from the MNO, and secondly, to validate the impact of DSS on the network by contrasting it with the current fixed spectrum sharing method employed by the MNO in urban and suburban settings, thus offering a realistic analysis. Key Performance Indicators (KPIs) on LTE, such as Downlink Throughput, Physical Resource Block (PRB) Utilization, and Evolved Radio Access Bearer (ERAB) Establishment, were evaluated, along with consideration of the impact on 2G metrics like voice call drops, total carried traffic, and receiver (Rx) signal quality. The simulations revealed a substantial surge in LTE throughput, averaging 62% across both clusters, resulting in an overall increase in LTE traffic by 34%, thanks to DSS implementation. Remarkably, this enhancement in LTE performance was achieved while ensuring minimal adverse effects on DCS performance. Notably, DSS's impact on the DCS network was more pronounced in urban areas, leading to a 7% reduction in voice traffic attributed to heightened interference in shared spectrum zones, leading to increased SINR. As a result, there was a 6% drop in DL quality samples (DL Rq), resulting in a 0.16% increase in voice call drops post-DSS activation. In suburban regions, both DSS and Fixed Spectrum Allocation (FSA) exhibited nearly identical DCS performance, with negligible impact, as indicated by a slight 1.7% decline in received signal quality compared to the urban cluster. To further optimize DCS performance within the DSS framework, future strategies suggest reducing the transmit power of resource elements in shared spectrum zones to mitigate interference with DCS channels.
- ItemOpen AccessDevelopment and validation of the School Clinical Rugby Measure (SCRuM) test battery: understanding the qualities or skills defining good male adolescent rugby union players(2020) Chiwaridzo, Matthew; Ferguson, Gillian D; Smits-Engelsman, Bouwien CMBackground: Globally, the number of schoolboy adolescents playing highly competitive rugby is increasing even in countries such as Zimbabwe hardly known for dominating international rugby events. Given the increased participation rates, burgeoning talent identification and recruitment programs and the reportedly high injury risk associated with competitive youth rugby in Zimbabwe and globally, the minimal qualities or skills defining good male adolescent rugby players need further clarification. This study assembled a testing battery and compared the anthropometric variables, physiological characteristics and rugby-specific game skills of Zimbabwean schoolboys to identify qualities and/or skills discriminating elite from sub-elite male adolescent rugby players and non-rugby players within and between Under 16 (U16) and U19 age categories. Methods: This study was structured in three phases. Phase I developed the School Clinical Rugby Measure (SCRuM) test battery based on amalgamated information derived from narrative literature review, qualitative study and two systematic reviews. Using mixed methods sequential explanatory study designs, Phase II refined the test battery through the evaluation of face and logical validity using key informants (n=5) and rugby experts (n=20), respectively. Subsequently, rugby coaches (n=30) assessed the practical feasibility of implementing each SCRuM test item in the local context considering test equipment, procedural and acceptability issues. Phase III evaluated the test-retest reliability of each SCRuM test item among a sample of elite U16s (n=41) and U19s (n=41). The final study in Phase III compared cross-sectional test performances of 208 athletes from different playing standards and age category to identify SCRuM test items discriminating (i) older (U19) players from younger (U16) players regardless of playing standards, and (ii) elite from both sub-elite and nonrugby players regardless of age. Results: Phase I produced the first version of the SCRuM test battery with 23 variables. Phase II reduced the constituent components to 15 variables. The test-retest reliability study showed high intraclass correlation coefficient (ICC>0.70) for all SCRuM test items except for the 5-m, 10-m speed tests and passing-for-accuracy test. Age category had a significant main effect on all SCRuM test items except for sum of seven skinfolds (p=0.45, η2 p=0.003). Playing standard had a significant main effect ii on all variables except for height (p=0.40, η2 p=0.01) and sum of seven skinfolds (p=0.11, η2 p =0.02). Upper-and-lower body muscular strength and power, prolonged high-intensity intermittent running ability, repeated high-intensity exercise performance ability, tackling, passing and catching significantly improved with increasing playing standards. However, the Yo-Yo intermittent recovery level 1 test, vertical jump test, tackling proficiency test and running-and-catching ability skills test demonstrated greater discriminative ability across playing standards among U16s. The 40-m speed test, 2-kg medicine ball chest throw test, repeated high-intensity exercise test, one-repetition maximum bench press and back squat tests, and passing ability skills test showed better discriminative validity for differentiating U19s by playing standards. Conclusion: Irrespective of playing standard and consistent with previous studies, all SCRuM test items significantly increased with age except for skinfolds measures. These results highlight the sensitivity of component SCRuM test items in discriminating younger (U16s) from older (U19s) athletes. U16 coaches should consider these differences when designing training interventions to assist with the development of prospective U19 players. However, prolonged high-intensity intermittent running ability, lower-body muscular power, tackling proficiency and running-andcatching ability demonstrated greater discriminative ability among U16s only, indicating a possible link to higher playing standards for that age category. Upper-body muscular power, upper-and-lowerbody muscular strength, 40-m sprinting ability, repeated high-intensity exercise performance ability, and passing ability significantly improved with playing standards among U19s, highlighting the physiological characteristics and game skills capable of differentiating elite male adolescent rugby players from both sub-elite or non-rugby players at that age category. Collectively, these findings provide insight to the high school rugby coaches into the qualities and skills contextually relevant for training for the attainment of higher playing standards in schoolboy rugby at distinct age categories.
- ItemOpen AccessAn economic and institutional analysis of community wildlife conservation in Zimbabwe(2015) Ntuli, Herbert; Muchapondwa, EdwinThis thesis focuses on the economics and institutional aspects of community wildlife conservation in the context of local communities living adjacent to the Gonarezhou NationalPark in Zimbabwe. A significant proportion of wildlife in Zimbabwe, and in Southern Africa in general, is managed as a common pool resource by communities under community-based natural resource management. Several challenges threaten conservation efforts at both local and higher levels, thus hindering its ability to bring about development that might improve the welfare of poor rural communities participating in wildlife conservation. The most pressing issues in the wildlife sector include: inability to extract resource rents from wildlife conservation that in turn affect household welfare in terms of total household income and reduction in poverty and inequality, lack of capacity by local communities to solve collective action problems or lack of incentives to self-organise, and lack of comparable successful outcomes in CBNRM communities such as the wildlife conservancy communities. Learning from other successful communities that use community-based' models, such as wildlife conservancies, might provide important insights for policy makers and development practitioners. These issues are explored in three substantial papers included in this thesis. The thesis consists of five chapters starting with an introduction, followed by three papers and finally conclusions and policy implications. The study makes use of purpose-collected primary data from local communities living adjacent to Gonarezhou National Park in Zimbabwe. The first paper investigates the effects of wildlife resources on community welfare. Specifically, the paper examines the contribution of environmental income to) total household income,) poverty reduction, and) reduction in income inequality. Furthermore, it investigates the impact of environmental income on households in different income categories, the role of wildlife in the portfolio of environmental income and the determinants of environmental income generated by different households. To achieve the objectives above, the paper makes use of income quintile analysis, the Foster-Greer-Thorbecke poverty measure, Gini coefficient analysis, Ginidecomposition analysis, ordered logit regression model and instrumental variables estimation using heteroscedasticity-based instruments. The results show that the relative contribution of environmental income towards total household income is more pronounced in poor households, while the relative contribution of agricultural income is noticeable in wealthier households. In particular, wealthier households consumed more wildlife products in total than relatively poor households. However, poorer households derive greater benefit from the consumption of wildlife resources than wealthier households. Excluding wildlife compromised the relative contribution of environmental income and, at the same time, increased the relative contribution of farm and wage income. Environmental income has more impact in terms of poverty and inequality reduction in the lower income quintiles than in the upper quintiles. Wildlife income alone accounted for about 5.5% reduction in the proportion of households living below the poverty line. Furthermore, wildlife income had an equalizing effect, bringing about a 5.4% reduction in measured inequality.
- ItemOpen AccessEvaluating the effectiveness of a multi-component intervention on early childhood development in paediatric HIV care and treatment programmes: a randomised controlled trial(BioMed Central, 2018-07-09) Chingono, R; Mebrahtu, H; Mupambireyi, Z; Simms, V; Weiss, H A; Ndlovu, P; Charasika, F; Tomlinson, M; Cluver, L D; Cowan, F M; Sherr, LBackground HIV infection in a family may affect optimum child development. Our hypothesis is that child development outcomes among HIV-exposed infants will be improved through a complex early childhood stimulation (ECS) programme, and income and loans saving programme for HIV positive parents. Methods The study was a cluster-randomized controlled trial in 30 clinic sites in two districts in Zimbabwe. Clinics were randomised in a 1:1 allocation ratio to the Child Health Intervention for Development Outcomes (CHIDO) intervention or Ministry of Health standard care. The CHIDO intervention comprises three elements: a group ECS parenting programme, an internal savings and lending scheme (ISALS) and case-management home visits by village health workers. The intervention was aimed at caregiver-child dyads (child aged 0–24 months) where the infant was HIV exposed or infected. The primary outcomes were cognitive development (assessed by the Mullen Scales of Early Learning) and retention of the child in HIV care, at 12 months after enrolment. A comprehensive process evaluation was conducted. Discussion The results of this cluster-randomised trial will provide important information regarding the effects of multi-component interventions in mitigating developmental delays in HIV-exposed infants living in resource-limited environments. Trial registration This trial is registered with the Pan African Clinical Trials Registry ( www.pactr.org ), registration number PACTR201701001387209; the trial was registered on 16th January 2017 (retrospectively registered).
- ItemOpen AccessExploring the role of development finance institutions in enhancing the financial and technical capacity of smallholder farmers for agribusiness integration: the case study of Zimbabwe(2025) Hove, Rumbidzai; Alhassan, Abdul LatifThe economic and social livelihoods of smallholder farmers in Zimbabwe have not improved despite them being holders of land as a key capital resource. Smallholder farmers are still marred with poverty and food insecurity challenges. The purpose of this research is to explore how the economic and social livelihoods of smallholder farmers can be improved to become more sustainable by devising strategies that will enable them to be integrated into the Agribusiness value chain. Helping smallholder farmers transform their farm operations into commercial operations, thereby integrating them into the agribusiness value chain, is the solution that will enable the economic and social livelihoods of smallholder farmers to be transformed. The study seeks to understand the financial and technical capacity challenges that smallholder farmers face and explore how the support of Development Finance Institutions can be leveraged to turn these challenges around. A qualitative approach was employed by conducting discussions with 30 farmers in the Chegutu region of Zimbabwe. The results indicate that farmers face a myriad of challenges that are driven by both external factors and internal factors. Firstly, farmers have significant gaps in their financial capacity caused by inadequate, volatile, and unstable income, and this causes a lack of investment capital, impacting their potential to scale up and increase land utilisation and farm productivity levels. Moreover, the farmers are not deriving sustainable benefits from farm activities, as displayed by the continuous reinvestment into their farms from non-farm income sources. Secondly, farmers have several gaps impacting their technical capacity to drive innovation and efficiencies in their farming operations. This is due to low levels of education and a lack of farm infrastructure. Thirdly, farmers are facing limitations in monetizing their produce in the local agricultural market, which is caused by structural inefficiencies, inability to access markets, and pricing and demand constraints. Lastly, farmers are not getting adequate institutional support to address the capacity challenges. The results from the discussion prompt a call for action; hence, targeted strategies are recommended for DFIs to consider implementing to support the farmers in deriving a financial benefit from their farms through agribusiness development.
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