Browsing by Subject "Hombre"

Now showing 1 - 6 of 6
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    Dosage adjustment in medical patients with renal impairment at Groote Schuur Hospital
    (2010) Decloedt, Eric; Leisegang, Rory; Blockman, Marc; Cohen, Karen
    BACKGROUND: Many drugs are eliminated by the kidneys and therefore may require dose adjustment in patients with renal impairment. The need for dose adjustment is frequently neglected by prescribers. METHODS: We reviewed folders of patients admitted to the Groote Schuur Hospital general medical wards between January and March 2008. Patients with renal impairment, defined as an estimated glomerular filtration rate (eGFR) < or = 50 ml per minute per 1.73 m2, were identified. In-patient prescriptions were captured if they were written after clinical notes indicated impaired renal function, or > or = 1 day after renal function tests were performed. We determined what proportion of these prescriptions required dose adjustment and whether drug doses were appropriately adjusted. RESULTS: We found renal impairment in 32% (97/301) of medical admissions. There were 615 prescription entries for the 97 patients with renal impairment. Dose adjustment was required in 19% (117/615) of prescription entries, and only 32% (37/117) of these prescription entries were correctly dose adjusted. Of 97 patients, 69 received one or more drugs that required dose adjustment (median 1, range 1 - 5). All drug doses were correctly adjusted in 12% (8/69) of patients. Importantly, in the majority of patients (59% (41/69)) no doses had been correctly adjusted. CONCLUSION: Consistent with international studies, drug dose adjustment in patients with renal impairment in a South African hospital was frequently neglected. Strategies to alert clinicians of the need for dose adjustment in renal impairment should be considered, including automated eGFR reporting and computerised aids to guide drug dosing, that account for renal impairment.
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    Far fewer missed opportunities for immunisation in an integrated child health service
    (1993) Harrison, David; Barron, Peter; Glass, Belinda; Sonday, Shahim; van der Heyde, Yolande
    The mobile nature of the population of Kayelitsha makes it imperative that opportunities for immunisation of children are exploited at every visit to health services. Previous studies have demonstrated a high incidence of missed opportunities for immunisation at curative health services. The occurrence of undetected opportunities for immunisation are compared at two primary care institutions: one in which curative and preventive services are provided separately, and one in which these functions are integrated. Far fewer opportunities for immunisation were missed at the integrated service, underscoring the urgency of integrating child health services throughout the country.The mobile nature of the population of Kayelitsha makes it imperative that opportunities for immunisation of children are exploited at every visit to health services. Previous studies have demonstrated a high incidence of missed opportunities for immunisation at curative health services. The occurrence of undetected opportunities for immunisation are compared at two primary care institutions: one in which curative and preventive services are provided separately, and one in which these functions are integrated. Far fewer opportunities for immunisation were missed at the integrated service, underscoring the urgency of integrating child health services throughout the country.
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    Health surveillance of employees on a lead mine, 1979-1989
    (1991) VAN HEERDEN, H; METS, J
    Health surveillance of employees at a lead mine in the northern Cape, employing about 1 400 people, is specifically aimed at early detection of excessive lead absorption, which is the main chemical hazard. Over a period of 9 years the blood lead level distribution showed very few values (2,5%) that exceeded 60 μg/100 ml.Health surveillance of employees at a lead mine in the northern Cape, employing about 1 400 people, is specifically aimed at early detection of excessive lead absorption, which is the main chemical hazard. Over a period of 9 years the blood lead level distribution showed very few values (2,5%) that exceeded 60 μg/100 ml.
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    Non-invasive management of organic impotence
    (1995) Kaplan, F J; Levitt, N S; Stevens, P J; Phillips, C
    OBJECTIVE: To establish the efficacy of a vacuum device (ErecAid) in the management of organic impotence. DESIGN: Cohort study; questionnaire before and after a 6-month study period. SETTING: Groote Schuur Hospital, Cape Town. PARTICIPANTS: A total of 19 men with organic impotence, 8 diabetic and 11 with previous pelvic surgery or radiotherapy. INTERVENTION: Vacuum device (ErecAid, Osbon Medical Systems). OUTCOME MEASURE: Efficacy of ErecAid. RESULTS: Six of 8 diabetics and 6 of 11 non-diabetics reported successful intercourse, while 16 of the participants would recommend the device to others. Some difficulty with the device was experienced by 11 and only 9 described an increase in self-esteem. CONCLUSION: Although some difficulties may be experienced in the use of the ErecAid, it clearly has a role to play in the management of patients with organic impotence, who ideally should be able to select their preferred form of therapy.
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    Presenting features of primary angle-closure glaucoma in patients of mixed ethnic background
    (1993) SALMON, J
    The relative frequency with which patients present with acute or chronic angle-closure glaucoma depends on their ethnic background. In order to examine the presenting features and effects of primary angle-closure glaucoma in people of mixed ethnicity, we reviewed all «coloured» patients who presented to Groote Schuur Hospital with this diagnosis during a 5-year period. Of the 92 patients, 33 (36%) presented with acute angle-closure glaucoma and 59 (64%) with chronic angleclosure glaucoma. The level of intra-ocular pressure on presentation correlated well with the number of quadrants of angle closure (correlation coefficient: r=0,73, P<0,001). When individual eyes were assessed, a mean cup/disc ratio of ≥0,8 was present in 35% (65/184) and glaucomatous visual field loss was present in 56,5% (104/184).The relative frequency with which patients present with acute or chronic angle-closure glaucoma depends on their ethnic background. In order to examine the presenting features and effects of primary angle-closure glaucoma in people of mixed ethnicity, we reviewed all «coloured» patients who presented to Groote Schuur Hospital with this diagnosis during a 5-year period. Of the 92 patients, 33 (36%) presented with acute angle-closure glaucoma and 59 (64%) with chronic angleclosure glaucoma. The level of intra-ocular pressure on presentation correlated well with the number of quadrants of angle closure (correlation coefficient: r=0,73, P<0,001). When individual eyes were assessed, a mean cup/disc ratio of ≥0,8 was present in 35% (65/184) and glaucomatous visual field loss was present in 56,5% (104/184).
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    The referral letter: a problem of communication
    (1991) Lachman, P I; Stander, I A
    This cross-sectional descriptive study assesses the letters sent with referred patients and makes appropriate recommendations. During the 6-month period 1 July-31 December 1987, 9288 letters were photocopied at the admissions offices of the hospital. Detailed analysis of 1143 (12,3%) letters was undertaken. The private sector, i.e. general practitioners, was the largest referral agency, followed by community-based day hospitals.This cross-sectional descriptive study assesses the letters sent with referred patients and makes appropriate recommendations. During the 6-month period 1 July-31 December 1987, 9288 letters were photocopied at the admissions offices of the hospital. Detailed analysis of 1143 (12,3%) letters was undertaken. The private sector, i.e. general practitioners, was the largest referral agency, followed by community-based day hospitals.