Browsing by Subject "Eclampsia"
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- ItemOpen AccessImminent eclampsia: the clinical state and the treatment with Avertin of 100 cases(1962) Craig, CecilThe term eclampsia is derived from the Greek eklampien meaning a flesh, and its etymology suggests the acute onset of the convulsions. On the surface, therefore, it would appear paradoxical to define any state as being one of "imminent eclampsia". However, although the aetiology is unknown, sufficient knowledge of the preceding history and manifestations of eclampsia has accumulated to justify such a specific term. In a subsequent chapter, these symptoms and signs will be assessed and discussed in detail. Where the net of antenatal care is widespread and where such services are accepted and utilized by all who are pregnant in a community, the incidence of severe toxania and eclampsia is minimal. Few obstetricians in highly developed, civilized areas are afforded the opportunities for studing and treating any large numbers of cases of imminent eclampaia
- ItemOpen AccessPost-partum trend in blood pressure levels, renal function and proteinuria in women with severe preeclampsia and eclampsia in Sub-Saharan Africa: A 6-months cohort study(BioMed Central Ltd, 2014) Kaze, Francois; Njukeng, Francis; Kengne, Andre-Pascal; Ashuntantang, Gloria; Mbu, Robinson; Halle, Marie; Asonganyi, TazoachaBACKGROUND: Preeclampsia and eclampsia, which are the most frequent hypertensive disorders in pregnancy, are associated with renal involvements. We aimed to assess the time trend in blood pressure levels, renal function and proteinuria after delivery, and investigate their determinants in Cameroonian women with severe preeclampsia and eclampsia. METHODS: This was a prospective cohort study involving 54 women with severe preeclampsia and eclampsia, conducted between July 2010 and February 2012 at the central maternity unit of the Yaounde Central Hospital. Clinical and laboratory parameters were recorded from day-1 to 6months after delivery. Mixed-linear and logistic regression models were used to relate baseline and within follow-up levels of covariates, with changes in blood pressure levels, renal function and proteinuria, as well as persisting hypertension, renal failure and proteinuria. RESULTS: During follow-up, a significant improvement was observed in blood pressure, renal function and proteinuria (all p<0.002). Thirteen (24.1%) patients with renal failure at delivery recovered completely within six weeks. Twenty-six (48.1%), 17 (31.5%) and 1 (1.8%) patients had persisting proteinuria at 6weeks, 3months and 6months post-delivery, respectively. Corresponding figures for persisting hypertension were 23 (42.6%), 15 (27.8%) and 8 (14.8%). Advanced age, higher body mass index, low gestational age at delivery, low fetal birth weight, and proteinuria at delivery were the main risk factors for persisting hypertension at 3months, meanwhile low fetal birth weight, severe preeclampsia and proteinuria at delivery were correlated with persisting proteinuria at 3months. Advanced age and higher body mass index were the only determinants of the composite outcome of persisting hypertension or proteinuria at three and six months. CONCLUSION: Hypertension and proteinuria are very common beyond the postpartum period in Cameroonian women with severe preeclampsia and eclampsia. Long-term follow-up of these women will help preventing and controlling related complications.