Browsing by Author "Scott, C"

Now showing 1 - 4 of 4
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    CANDLE SYNDROME: Orodfacial manifestations and dental implications
    (BioMed Central, 2015-12-28) Roberts, T; Stephen, L; Scott, C; di Pasquale, T; Naser-eldin, A; Chetty, M; Shaik, S; Lewandowski, L; Beighton, P
    A South African girl with CANDLE Syndrome is reported with emphasis on the orodental features and dental management. Clinical manifestations included short stature, wasting of the soft tissue of the arms and legs, erythematous skin eruptions and a prominent abdomen due to hepatosplenomegaly. Generalized microdontia, confirmed by tooth measurement and osteopenia of her jaws, confirmed by digitalized radiography, were previously undescribed syndromic components. Intellectual impairment posed problems during dental intervention. The carious dental lesions and poor oral hygiene were treated conservatively under local anaesthetic. Prophylactic antibiotics were administered an hour before all procedures. Due to the nature of her general condition, invasive dental procedures were minimal. Regular follow-ups were scheduled at six monthly intervals. During this period, her overall oral health status had improved markedly. The CANDLE syndrome is a rare condition with grave complications including immunosuppression and diabetes mellitus. As with many genetic disorders, the dental manifestations are often overshadowed by other more conspicuous and complex syndromic features. Recognition of both the clinical and oral changes that occur in the CANDLE syndrome facilitates accurate diagnosis and appropriate dental management of this potentially lethal condition.
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    PReS-FINAL-2253: A case series of HIV arthropathy in Cape Town
    (BioMed Central Ltd, 2013) Webb, K; Scott, C; Brice, N
    HIV arthropathy is well described in adults. Few studies have looked in depth at HIV arthropathy in children, and the characteristics of this entity have not been fully described.
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    PReS-FINAL-2268: Sarcoidosis in children seen at the pediatric rheumatology clinics of two referral hospitals in Cape Town, South Africa
    (BioMed Central Ltd, 2013) Okong'o, LO; Scott, C; Webb, K
    Sarcoidosis is a relatively uncommon condition in children. Reports from multiracial societies such as the USA indicate that sarcoidosis is more common in Africans than other racial groups. However, few reports of cases of childhood Sarcoidosis have been published from sub-Saharan Africa to shed light on the burden of sarcoidosis and the demographics and clinical presentation of children diagnosed with sarcoidosis.
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    PW03-022 - Neutrophilic skin disease and inflammation
    (BioMed Central Ltd, 2013) Webb, K; Hlela, C; Scott, C
    Robert Sweet first described a syndrome with a painful, erythematous nodular plaques, neutrophilic dermal infiltrates, fevers and peripheral neutrophilia. This cluster of syndromes became known as Sweet's syndrome. There have been many published cases in children of neutrophilic dermatoses and fever which are labeled as Sweet's syndrome. Recently, however, neutrophilic dermatoses have been associated with some autoimmune and autoinflammatory diseases .