Browsing by Author "Cuzen, Natalie"

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    Disinhibition in South African treatment-naïve adolescents with alcohol use disorders
    (2012) Cuzen, Natalie; Thomas, Kevin
    The concept of the disinhibitory complex refers to a cluster of personality, psychiatric, cognitive, and electrophysiological inhibitory control impairments that have been documented in alcohol use disorders (AUDs). Previous AUD research has focused on treatment-seeking adults with comorbid psychopathology; with regard to the disinhibitory complex, such individuals are likely to differ from younger, treatment-naïve individuals, such as the sample here studied. Further, few studies have examined several domains of disinhibition simultaneously, and so little is known about relationships between the various correlates of disinhibition. This study aimed to (a) examine and characterize the disinhibitory complex in treatment-naïve adolescents with AUDs, (b) investigate sex differences in disinhibition, and (c) determine whether an underlying construct of disinhibition might explain elevated levels of disinhibition in AUDs observed on individual indices.