Browsing by Author "Cotton, Jonathan"

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    Fluorescent ajoenes as a mechanistic probe for cancer
    (2010) Cotton, Jonathan; Hunter, Roger; Caira, Mino R; Parker, Iqbal
    This thesis describes the development and synthesis of several novel ajoene mimics. The first of which, (E/Z)-1,8-(Bis-p-methoxyphenyl)-2,3,7-trithia-octa-4-ene 7-oxide 17, was developed as a continuation of SAR studies performed by our group, involved the placing p-methoxyphenly groups on the termini of the ajoene pharmacophore.