Browsing by Author "Coetzee, D"

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    Inflammation in the male genital tract: implications for HIV acquisition and transmission
    (BioMed Central Ltd, 2012) Olivier, Abraham Jacobus; Roberts, L; Coetzee, D; Williamson, A; Passmore, JS; Burgers, WA
    Elevated plasma levels of pro-inflammatory mediators such as TNFα, IL-1β, IL-6 and IL-8, MIP-1α, MIP-1β and RANTES have been demonstrated in HIV-infected individuals and HIV induces higher levels of pro-inflammatory cytokines in the female genital tract. We characterized levels of inflammation in semen, to gain an understanding of factors influencing transmission and acquisition in the male genital tract. Our hypothesis was that infected men would exhibit higher levels of inflammation in semen than uninfected men.
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    The prevention of mother-to-child HIV transmission programme and infant feeding practices
    (2003) Hilderbrand, K; Goemaere, E; Coetzee, D
    Since the first cases of HIV transmission through breastfeeding were documented, a fierce debate has raged on appropriate guidelines for infant feeding in resource-poor settings. A major problem is determining when it is safe and feasible to formula-feed, as breast-milk protects against other diseases. A cross-sectional survey of 113 women attending the programme for the prevention of mother-to-child transmission in Khayelitsha, Cape Town, was conducted. Over 95% of women on the programme formula-fed their infants and did not breast- feed at all. Seventy per cent of women said that their infant had never had diarrhoea, and only 3% of children had had two episodes of diarrhoea. Focus groups identified the main reasons for not breast-feeding given by women to their families and those around them. Formula feeding is safe and feasible in an urban environment where sufficient potable water is available.