Browsing by Author "Bodmer, Walter"

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    The molecular genetic and epidemiological investigation of colorectal cancer in South Africa
    (2003) Felix, Rebecca; Ramesar, Rajkumar; Bodmer, Walter
    Cancer of the colon and rectum is the third-most common cause of death due to neoplasia in Western countries. Colorectal cancer (CRC) can broadly be divided into the hereditary, non-hereditary and sporadic forms. Hereditary cancers account for approximately 10% of the CRCs. Familial cancers can be divided into thos types in which polyps are a dominant feature (e.g. familal adenomatous polyposis-FAP) and the non-polypotic forms (e.g. hereditary nonpolyposis colorectal cancers-HNPCC).