Investigating cross-clade immune responses in HIV-1 subtype C-infected individuals from South Africa

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dc.contributor.advisorBurgers, Wendyen_ZA
dc.contributor.authorZembe, Lyciasen_ZA
dc.date.accessioned2015-05-06T07:11:00Z
dc.date.available2015-05-06T07:11:00Z
dc.date.issued2007en_ZA
dc.descriptionIncludes bibliographical references (leaves 114-147).en_ZA
dc.description.abstractThe increasing diversity of HIV-1 in different geographic regions presents a challenge for the development of an HIV/AIDS vaccine. Even if proven effective, the ability of a vaccine to have cross-subtype and intra-subtype protection remains an important question. The aim of the study was to investigate cross- and intra-clade T cell immune responses in HIV-1 subtype C-infected individuals. The objectives were to genetically characterise full length gag gene sequences from individuals chronically infected with HIV-1 and then assess the degree of cross-reactive immune responses in an ELlS pot assay using peptide reagents based on vaccine candidates.en_ZA
dc.identifier.apacitationZembe, L. (2007). <i>Investigating cross-clade immune responses in HIV-1 subtype C-infected individuals from South Africa</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Virology. Retrieved from http://hdl.handle.net/11427/12731en_ZA
dc.identifier.chicagocitationZembe, Lycias. <i>"Investigating cross-clade immune responses in HIV-1 subtype C-infected individuals from South Africa."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Virology, 2007. http://hdl.handle.net/11427/12731en_ZA
dc.identifier.citationZembe, L. 2007. Investigating cross-clade immune responses in HIV-1 subtype C-infected individuals from South Africa. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Zembe, Lycias AB - The increasing diversity of HIV-1 in different geographic regions presents a challenge for the development of an HIV/AIDS vaccine. Even if proven effective, the ability of a vaccine to have cross-subtype and intra-subtype protection remains an important question. The aim of the study was to investigate cross- and intra-clade T cell immune responses in HIV-1 subtype C-infected individuals. The objectives were to genetically characterise full length gag gene sequences from individuals chronically infected with HIV-1 and then assess the degree of cross-reactive immune responses in an ELlS pot assay using peptide reagents based on vaccine candidates. DA - 2007 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2007 T1 - Investigating cross-clade immune responses in HIV-1 subtype C-infected individuals from South Africa TI - Investigating cross-clade immune responses in HIV-1 subtype C-infected individuals from South Africa UR - http://hdl.handle.net/11427/12731 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/12731
dc.identifier.vancouvercitationZembe L. Investigating cross-clade immune responses in HIV-1 subtype C-infected individuals from South Africa. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Virology, 2007 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/12731en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDivision of Virologyen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherMedical Virologyen_ZA
dc.titleInvestigating cross-clade immune responses in HIV-1 subtype C-infected individuals from South Africaen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMScen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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