The management of corneal graft rejection

dc.contributor.authorHill, John Clifford
dc.date.accessioned2025-05-27T13:05:43Z
dc.date.available2025-05-27T13:05:43Z
dc.date.issued1994
dc.date.updated2024-08-20T13:32:53Z
dc.description.abstractDescriptions of corneal disease and suggested treatments have been documented since the ancient civilisations of Egypt and Greece. However, in these cultures corneal surgery was limited to various types of superficial keratectomy. The idea of corneal grafting was suggested relatively recently3,4• Guillaume Pellier de 22 Quengsy5, a Frenchman, suggested in 1789 the complete replacement of the opaque cornea using a thin glass disc the size of the cornea and set in a silver rim. He suggested that it could be stitched in with cotton threads and designed instruments for the operation although he never performed the procedure himself. This idea was really the forerunner of the modem keratoprothesis. At the end of the 18th and beginning of the 19th century there was a stimulus for corneal grafting as a result of blindness from diseases such as smallpox, venereal disease, and trachoma brought back by soldiers in the Napoleonic wars. It is uncertain who first suggested the replacement of damaged corneas with living tissue, but the credit is usually attributed to Franz Reisinger6 who also coined the term 11 keratoplasty11 • Reisinger confined his work to rabbits and chickens but most grafts failed either from opacification or sepsis. His work, however, did stimulate debate over the feasibility of keratoplasty, but many were extremely sceptical including one of Berlin's great surgeons of the time, Dieffenbach. He wrote in 18312 that Reisinger's idea of keratoplasty was 11 ••• certainly one of the most audacious fantasies, and it would be the highest reward of surgery if this operation succeeded 11 •
dc.identifier.apacitationHill, J. C. (1994). <i>The management of corneal graft rejection</i>. (). ,Faculty of Health Sciences ,Department of Medicine. Retrieved from http://hdl.handle.net/11427/41444en_ZA
dc.identifier.chicagocitationHill, John Clifford. <i>"The management of corneal graft rejection."</i> ., ,Faculty of Health Sciences ,Department of Medicine, 1994. http://hdl.handle.net/11427/41444en_ZA
dc.identifier.citationHill, J.C. 1994. The management of corneal graft rejection. . ,Faculty of Health Sciences ,Department of Medicine. http://hdl.handle.net/11427/41444en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Hill, John Clifford AB - Descriptions of corneal disease and suggested treatments have been documented since the ancient civilisations of Egypt and Greece. However, in these cultures corneal surgery was limited to various types of superficial keratectomy. The idea of corneal grafting was suggested relatively recently3,4• Guillaume Pellier de 22 Quengsy5, a Frenchman, suggested in 1789 the complete replacement of the opaque cornea using a thin glass disc the size of the cornea and set in a silver rim. He suggested that it could be stitched in with cotton threads and designed instruments for the operation although he never performed the procedure himself. This idea was really the forerunner of the modem keratoprothesis. At the end of the 18th and beginning of the 19th century there was a stimulus for corneal grafting as a result of blindness from diseases such as smallpox, venereal disease, and trachoma brought back by soldiers in the Napoleonic wars. It is uncertain who first suggested the replacement of damaged corneas with living tissue, but the credit is usually attributed to Franz Reisinger6 who also coined the term 11 keratoplasty11 • Reisinger confined his work to rabbits and chickens but most grafts failed either from opacification or sepsis. His work, however, did stimulate debate over the feasibility of keratoplasty, but many were extremely sceptical including one of Berlin's great surgeons of the time, Dieffenbach. He wrote in 18312 that Reisinger's idea of keratoplasty was 11 ••• certainly one of the most audacious fantasies, and it would be the highest reward of surgery if this operation succeeded 11 • DA - 1994 DB - OpenUCT DP - University of Cape Town KW - Medicine LK - https://open.uct.ac.za PY - 1994 T1 - The management of corneal graft rejection TI - The management of corneal graft rejection UR - http://hdl.handle.net/11427/41444 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/41444
dc.identifier.vancouvercitationHill JC. The management of corneal graft rejection. []. ,Faculty of Health Sciences ,Department of Medicine, 1994 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/41444en_ZA
dc.language.rfc3066eng
dc.publisher.departmentDepartment of Medicine
dc.publisher.facultyFaculty of Health Sciences
dc.subjectMedicine
dc.titleThe management of corneal graft rejection
dc.typeThesis / Dissertation
dc.type.qualificationlevelDoctoral
dc.type.qualificationlevelPhD
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