HIV-associated neurocognitive disorders biomarkers and the response to antiretroviral therapy

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dc.contributor.advisorCombrinck, MIen_ZA
dc.contributor.authorCross, Helen Margoten_ZA
dc.date.accessioned2015-01-08T19:51:16Z
dc.date.available2015-01-08T19:51:16Z
dc.date.issued2012en_ZA
dc.descriptionIncludes bibliographical references.en_ZA
dc.description.abstractThis study aimed to determine whether highly active antiretroviral therapy (HAART) improved cognitive function in HIV positive people in South Africa, and whether this effect differed according to the CNS penetration-effectiveness (CPE) of the regimen used. I also investigated potential HIV-Associated Neurocognitive Disorders (HAND) biomarkers (serum neopterin, osteopontin and neurofilament H) to determine their relationship to the severity of cognitive impairment at baseline in HAART-naïve patients, and whether initial levels of these biomarkers related to the change in cognitive function a year later.en_ZA
dc.identifier.apacitationCross, H. M. (2012). <i>HIV-associated neurocognitive disorders biomarkers and the response to antiretroviral therapy</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Neurosurgery. Retrieved from http://hdl.handle.net/11427/11759en_ZA
dc.identifier.chicagocitationCross, Helen Margot. <i>"HIV-associated neurocognitive disorders biomarkers and the response to antiretroviral therapy."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Neurosurgery, 2012. http://hdl.handle.net/11427/11759en_ZA
dc.identifier.citationCross, H. 2012. HIV-associated neurocognitive disorders biomarkers and the response to antiretroviral therapy. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Cross, Helen Margot AB - This study aimed to determine whether highly active antiretroviral therapy (HAART) improved cognitive function in HIV positive people in South Africa, and whether this effect differed according to the CNS penetration-effectiveness (CPE) of the regimen used. I also investigated potential HIV-Associated Neurocognitive Disorders (HAND) biomarkers (serum neopterin, osteopontin and neurofilament H) to determine their relationship to the severity of cognitive impairment at baseline in HAART-naïve patients, and whether initial levels of these biomarkers related to the change in cognitive function a year later. DA - 2012 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2012 T1 - HIV-associated neurocognitive disorders biomarkers and the response to antiretroviral therapy TI - HIV-associated neurocognitive disorders biomarkers and the response to antiretroviral therapy UR - http://hdl.handle.net/11427/11759 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/11759
dc.identifier.vancouvercitationCross HM. HIV-associated neurocognitive disorders biomarkers and the response to antiretroviral therapy. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Neurosurgery, 2012 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/11759en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDivision of Neurosurgeryen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherNeuroscienceen_ZA
dc.titleHIV-associated neurocognitive disorders biomarkers and the response to antiretroviral therapyen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMMeden_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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