Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores

 

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dc.contributor.advisor Chibale, Kelly en_ZA
dc.contributor.author Nair, Shankari en_ZA
dc.date.accessioned 2014-11-28T09:53:50Z
dc.date.available 2014-11-28T09:53:50Z
dc.date.issued 2012 en_ZA
dc.identifier.citation Nair, S. 2012. Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores. University of Cape Town. en_ZA
dc.identifier.uri http://hdl.handle.net/11427/9805
dc.description Includes bibliographical references. en_ZA
dc.description.abstract Malaria stills remains one of the leading causes of death in sub-Saharan Africa, with P. falciparum being the most virulent strain of Plasmodium. Due to the emergence of drug resistance, new antimalarial agents are needed to circumvent this. Similarly, in the treatment of cancer, there is an urgent need for the design and development of new antineoplastic agents. This work describes the design, synthesis and biological evaluation of chromone-aminoquinoline hybrids as potentially new chemotherapeutic agents. en_ZA
dc.language.iso eng en_ZA
dc.subject.other Chemistry en_ZA
dc.title Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores en_ZA
dc.type Master Thesis
uct.type.publication Research en_ZA
uct.type.resource Thesis en_ZA
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Science en_ZA
dc.publisher.department Department of Chemistry en_ZA
dc.type.qualificationlevel Masters
dc.type.qualificationname MSc en_ZA
uct.type.filetype Text
uct.type.filetype Image
dc.identifier.apacitation Nair, S. (2012). <i>Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores</i>. (Thesis). University of Cape Town ,Faculty of Science ,Department of Chemistry. Retrieved from http://hdl.handle.net/11427/9805 en_ZA
dc.identifier.chicagocitation Nair, Shankari. <i>"Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores."</i> Thesis., University of Cape Town ,Faculty of Science ,Department of Chemistry, 2012. http://hdl.handle.net/11427/9805 en_ZA
dc.identifier.vancouvercitation Nair S. Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores. [Thesis]. University of Cape Town ,Faculty of Science ,Department of Chemistry, 2012 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/9805 en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Nair, Shankari AB - Malaria stills remains one of the leading causes of death in sub-Saharan Africa, with P. falciparum being the most virulent strain of Plasmodium. Due to the emergence of drug resistance, new antimalarial agents are needed to circumvent this. Similarly, in the treatment of cancer, there is an urgent need for the design and development of new antineoplastic agents. This work describes the design, synthesis and biological evaluation of chromone-aminoquinoline hybrids as potentially new chemotherapeutic agents. DA - 2012 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2012 T1 - Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores TI - Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores UR - http://hdl.handle.net/11427/9805 ER - en_ZA


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