Delayed graft function in renal transplantation : aetiology and impact on graft outcome

 

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dc.contributor.advisor Kahn, D en_ZA
dc.contributor.author Douie, Walter James Percival en_ZA
dc.date.accessioned 2014-10-24T07:32:08Z
dc.date.available 2014-10-24T07:32:08Z
dc.date.issued 2001 en_ZA
dc.identifier.citation Douie, W. 2001. Delayed graft function in renal transplantation : aetiology and impact on graft outcome. University of Cape Town. en_ZA
dc.identifier.uri http://hdl.handle.net/11427/8747
dc.description Bibliography: leaves 61-75. en_ZA
dc.description.abstract The optimal therapy for most patients with end stage renal disease is renal transplantation. This form of therapy results in improved quality of life, decreased medical expense, and perhaps a survival advantage for the recipient. Renal transplantation is however a complex form of therapy which may be associated with significant complications. The most common allograft complication post transplantation is the development of delayed graft function with a reported incidence of between 23 to 34%. This is a costly complication requiring ongoing dialysis and prolonged hospitalization. It also has a significant emotional impact on the patient and their family. Of greater concern though are the reports in the literature which associate delayed graft function with decreased graft survival. With current organ shortages organ donor criteria have been expanded to match the shortage. It is thus imperative that we should understand the mechanisms of graft damage which may result in delayed graft function. A better understanding of the relationship between delayed graft function and graft survival might significantly impact on our practice in certain settings such as in the use of organs harvested from a marginal donor. en_ZA
dc.language.iso eng en_ZA
dc.subject.other Surgery en_ZA
dc.title Delayed graft function in renal transplantation : aetiology and impact on graft outcome en_ZA
dc.type Master Thesis
uct.type.publication Research en_ZA
uct.type.resource Thesis en_ZA
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Health Sciences en_ZA
dc.publisher.department Department of Surgery en_ZA
dc.type.qualificationlevel Masters
dc.type.qualificationname MMed en_ZA
uct.type.filetype Text
uct.type.filetype Image
dc.identifier.apacitation Douie, W. J. P. (2001). <i>Delayed graft function in renal transplantation : aetiology and impact on graft outcome</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Department of Surgery. Retrieved from http://hdl.handle.net/11427/8747 en_ZA
dc.identifier.chicagocitation Douie, Walter James Percival. <i>"Delayed graft function in renal transplantation : aetiology and impact on graft outcome."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Department of Surgery, 2001. http://hdl.handle.net/11427/8747 en_ZA
dc.identifier.vancouvercitation Douie WJP. Delayed graft function in renal transplantation : aetiology and impact on graft outcome. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Department of Surgery, 2001 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/8747 en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Douie, Walter James Percival AB - The optimal therapy for most patients with end stage renal disease is renal transplantation. This form of therapy results in improved quality of life, decreased medical expense, and perhaps a survival advantage for the recipient. Renal transplantation is however a complex form of therapy which may be associated with significant complications. The most common allograft complication post transplantation is the development of delayed graft function with a reported incidence of between 23 to 34%. This is a costly complication requiring ongoing dialysis and prolonged hospitalization. It also has a significant emotional impact on the patient and their family. Of greater concern though are the reports in the literature which associate delayed graft function with decreased graft survival. With current organ shortages organ donor criteria have been expanded to match the shortage. It is thus imperative that we should understand the mechanisms of graft damage which may result in delayed graft function. A better understanding of the relationship between delayed graft function and graft survival might significantly impact on our practice in certain settings such as in the use of organs harvested from a marginal donor. DA - 2001 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2001 T1 - Delayed graft function in renal transplantation : aetiology and impact on graft outcome TI - Delayed graft function in renal transplantation : aetiology and impact on graft outcome UR - http://hdl.handle.net/11427/8747 ER - en_ZA


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