Investigation of the crystallisation inhibitory properties of albumin isolated from the urine of Black and White South Africans

 

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dc.contributor.author Mensah, Priscilla DNA en_ZA
dc.date.accessioned 2014-09-11T06:49:42Z
dc.date.available 2014-09-11T06:49:42Z
dc.date.issued 2004 en_ZA
dc.identifier.citation Mensah, P. 2004. Investigation of the crystallisation inhibitory properties of albumin isolated from the urine of Black and White South Africans. University of Cape Town. en_ZA
dc.identifier.uri http://hdl.handle.net/11427/7423
dc.description Bibliography: leaves 81-94. en_ZA
dc.description.abstract Stone incidence in South African blacks is extremely rare. The hypothesis to be tested is whether this apparent immunity can be attributed to the presence of more potent inhibitors of calcium oxalate (CaOx) crystallisation in urine from blacks compared to those occurring in the urine of white subjects. Urinary proteins have been shown to be inhibitors. This study investigated the crystallisation inhibitory properties of albumin isolated from the urine of healthy black (BA) and healthy white (WA) South Africans as well as those of human serum albumin (HSA). Albumin was selected because previous studies on other population groups had revealed that the protein inhibits CaOx aggregation. This observation is significant because crystal aggregation is considered to be more important for stone formation than crystal nucleation or growth. en_ZA
dc.language.iso eng en_ZA
dc.subject.other Chemistry en_ZA
dc.title Investigation of the crystallisation inhibitory properties of albumin isolated from the urine of Black and White South Africans en_ZA
dc.type Master Thesis
uct.type.publication Research en_ZA
uct.type.resource Thesis en_ZA
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Science en_ZA
dc.publisher.department Department of Chemistry en_ZA
dc.type.qualificationlevel Masters
dc.type.qualificationname MSc en_ZA
uct.type.filetype Text
uct.type.filetype Image
dc.identifier.apacitation Mensah, P. D. (2004). <i>Investigation of the crystallisation inhibitory properties of albumin isolated from the urine of Black and White South Africans</i>. (Thesis). University of Cape Town ,Faculty of Science ,Department of Chemistry. Retrieved from http://hdl.handle.net/11427/7423 en_ZA
dc.identifier.chicagocitation Mensah, Priscilla DNA. <i>"Investigation of the crystallisation inhibitory properties of albumin isolated from the urine of Black and White South Africans."</i> Thesis., University of Cape Town ,Faculty of Science ,Department of Chemistry, 2004. http://hdl.handle.net/11427/7423 en_ZA
dc.identifier.vancouvercitation Mensah PD. Investigation of the crystallisation inhibitory properties of albumin isolated from the urine of Black and White South Africans. [Thesis]. University of Cape Town ,Faculty of Science ,Department of Chemistry, 2004 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/7423 en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Mensah, Priscilla DNA AB - Stone incidence in South African blacks is extremely rare. The hypothesis to be tested is whether this apparent immunity can be attributed to the presence of more potent inhibitors of calcium oxalate (CaOx) crystallisation in urine from blacks compared to those occurring in the urine of white subjects. Urinary proteins have been shown to be inhibitors. This study investigated the crystallisation inhibitory properties of albumin isolated from the urine of healthy black (BA) and healthy white (WA) South Africans as well as those of human serum albumin (HSA). Albumin was selected because previous studies on other population groups had revealed that the protein inhibits CaOx aggregation. This observation is significant because crystal aggregation is considered to be more important for stone formation than crystal nucleation or growth. DA - 2004 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2004 T1 - Investigation of the crystallisation inhibitory properties of albumin isolated from the urine of Black and White South Africans TI - Investigation of the crystallisation inhibitory properties of albumin isolated from the urine of Black and White South Africans UR - http://hdl.handle.net/11427/7423 ER - en_ZA


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