The role of melanin production in the survival of Vibrio cholerae in the marine environment

Doctoral Thesis

2006

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University of Cape Town

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The marine bacterium Vibrio cholerae produces pyomelanin through the catabolism of L-tyrosine to homogentisic acid. Various types of melanins are used by microbes as defense mechanisms against a variety of environmental stresses. This thesis investigated the defensive role of V. cholerae pyomelanin against exogenous stresses, particularly hydrogen-peroxide (H2O2).
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Includes bibliographical references (p. 141-165).

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