Characterization of molecular and functional changes regulating hypobaric hypoxia-induced right ventricular hypertrophy

 

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dc.contributor.advisor Essop, M Faadiel en_ZA
dc.contributor.author Zungu, Makhosazane en_ZA
dc.date.accessioned 2014-07-29T09:38:49Z
dc.date.available 2014-07-29T09:38:49Z
dc.date.issued 2007 en_ZA
dc.identifier.citation Zungu, M. 2007. Characterization of molecular and functional changes regulating hypobaric hypoxia-induced right ventricular hypertrophy. University of Cape Town. en_ZA
dc.identifier.uri http://hdl.handle.net/11427/3498
dc.description Includes bibliographical references.
dc.description.abstract The major finding of this part of the study is that in vivo Wy-14,643 admnistration elicited direct effects on mitochondrial respiratory function and cardiac contractility. The data show that Wy-14,643 treatment attenuated mitochondrial respiration (state 3 respiration and rate of ADP phosphorylation) in the RV while promoting uncoupling of mitochondrial oxidative phosphorylation (increased state 4 respiration and basal leak) in the LV. en_ZA
dc.language.iso eng en_ZA
dc.subject.other Medicine en_ZA
dc.title Characterization of molecular and functional changes regulating hypobaric hypoxia-induced right ventricular hypertrophy en_ZA
dc.type Doctoral Thesis
uct.type.publication Research en_ZA
uct.type.resource Thesis en_ZA
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Health Sciences en_ZA
dc.publisher.department Department of Medicine en_ZA
dc.type.qualificationlevel Doctoral
dc.type.qualificationname PhD en_ZA
uct.type.filetype Text
uct.type.filetype Image
dc.identifier.apacitation Zungu, M. (2007). <i>Characterization of molecular and functional changes regulating hypobaric hypoxia-induced right ventricular hypertrophy</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Department of Medicine. Retrieved from http://hdl.handle.net/11427/3498 en_ZA
dc.identifier.chicagocitation Zungu, Makhosazane. <i>"Characterization of molecular and functional changes regulating hypobaric hypoxia-induced right ventricular hypertrophy."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2007. http://hdl.handle.net/11427/3498 en_ZA
dc.identifier.vancouvercitation Zungu M. Characterization of molecular and functional changes regulating hypobaric hypoxia-induced right ventricular hypertrophy. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2007 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/3498 en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Zungu, Makhosazane AB - The major finding of this part of the study is that in vivo Wy-14,643 admnistration elicited direct effects on mitochondrial respiratory function and cardiac contractility. The data show that Wy-14,643 treatment attenuated mitochondrial respiration (state 3 respiration and rate of ADP phosphorylation) in the RV while promoting uncoupling of mitochondrial oxidative phosphorylation (increased state 4 respiration and basal leak) in the LV. DA - 2007 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2007 T1 - Characterization of molecular and functional changes regulating hypobaric hypoxia-induced right ventricular hypertrophy TI - Characterization of molecular and functional changes regulating hypobaric hypoxia-induced right ventricular hypertrophy UR - http://hdl.handle.net/11427/3498 ER - en_ZA


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