Detailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington disease

Scholefield, Janine

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dc.contributor.advisor	Greenberg, Jacquie	en_ZA
dc.contributor.advisor	Goliath, Rene	en_ZA
dc.contributor.author	Scholefield, Janine	en_ZA
dc.date.accessioned	2014-07-29T09:10:20Z
dc.date.available	2014-07-29T09:10:20Z
dc.date.issued	2005	en_ZA
dc.identifier.citation	Scholefield, J. 2005. Detailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington disease. University of Cape Town.	en_ZA
dc.identifier.uri	http://hdl.handle.net/11427/3460
dc.description	Includes bibliographical references (leaves 113-124).
dc.description.abstract	The primary aim of this study was to investigate the origins of the HD mutation in South Africa (SA) by constructing a single nucleotide polymorphism (SNP) haplotype around the IT15 gene and to determine how many haplotypes there are in SA. Haplotypes were created by genotyping 6 SNPs in a total of 15 HD families. These families were comprised of seven Caucasian, 6 Mixed Ancestry and two Black African families.	en_ZA
dc.language.iso	eng	en_ZA
dc.subject.other	Medicine	en_ZA
dc.title	Detailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington disease	en_ZA
dc.type	Master Thesis
uct.type.publication	Research	en_ZA
uct.type.resource	Thesis	en_ZA
dc.publisher.institution	University of Cape Town
dc.publisher.faculty	Faculty of Health Sciences	en_ZA
dc.publisher.department	Department of Medicine	en_ZA
dc.type.qualificationlevel	Masters
dc.type.qualificationname	MSc	en_ZA
uct.type.filetype	Text
uct.type.filetype	Image
dc.identifier.apacitation	Scholefield, J. (2005). <i>Detailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington disease</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Department of Medicine. Retrieved from http://hdl.handle.net/11427/3460	en_ZA
dc.identifier.chicagocitation	Scholefield, Janine. <i>"Detailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington disease."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2005. http://hdl.handle.net/11427/3460	en_ZA
dc.identifier.vancouvercitation	Scholefield J. Detailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington disease. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2005 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/3460	en_ZA
dc.identifier.ris	TY - Thesis / Dissertation AU - Scholefield, Janine AB - The primary aim of this study was to investigate the origins of the HD mutation in South Africa (SA) by constructing a single nucleotide polymorphism (SNP) haplotype around the IT15 gene and to determine how many haplotypes there are in SA. Haplotypes were created by genotyping 6 SNPs in a total of 15 HD families. These families were comprised of seven Caucasian, 6 Mixed Ancestry and two Black African families. DA - 2005 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2005 T1 - Detailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington disease TI - Detailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington disease UR - http://hdl.handle.net/11427/3460 ER -	en_ZA