Investigating the role of growth hormone receptor in oesophageal squamous-cell carcinoma.
Master Thesis
2013
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University of Cape Town
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Abstract
Squamous-cell carcinoma of the oesophagus is a formidable disease which poses a significant health risk in developing countries where incidence is high and survival is low. Investigating the poorly understood mechanisms involved in oesophageal tumourigenesis may provide a platform to develop improved diagnostic techniques and therapies. The growth hormone (GH) signalling axis is important for proper cellular and organ system function. The axis has been shown to play a role in a number of cancers.
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Krivochiev, B. 2013. Investigating the role of growth hormone receptor in oesophageal squamous-cell carcinoma. University of Cape Town.