The investigation and assessment of Nutritional and Traditional Supplement products for content validity, contamination and adulteration

 

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dc.contributor.advisor Lambert, Mike en_ZA
dc.contributor.advisor Smith, Peter en_ZA
dc.contributor.author Gabriels, Gary Anthony en_ZA
dc.date.accessioned 2014-07-28T18:18:53Z
dc.date.available 2014-07-28T18:18:53Z
dc.date.issued 2013 en_ZA
dc.identifier.citation Gabriels, G. 2013. The investigation and assessment of Nutritional and Traditional Supplement products for content validity, contamination and adulteration. University of Cape Town. en_ZA
dc.identifier.uri http://hdl.handle.net/11427/3281
dc.description Includes abstract.
dc.description Includes bibliographical references.
dc.description.abstract Nutritional supplements are used by competitive and recreational athletes of all ages. As a consequence the supplement industry has grown to meet the increasing demand. The regulation of the supplement industry is unrefined, which increases the risk of the nutritional supplements being contaminated. Contamination may be intentional, where the companies “spike” their products with an ergogenic aid, or unintentional. A consequence of contamination is that an athlete may fail a drug test after ingesting a contaminated supplement or there may be negative health consequences. Without adequate legislation it is difficult to control the industry and reduce the risk of contamination in the supplement. Objectives: To investigate the industry associated with commercially available nutritional and traditional supplements. These are in the five specific areas; (i) to review the regulations and legislations, and labelling and claims associated with nutritional products in the USA, European Union and South Africa, (ii) to assess the labelling and claims information on nutritional supplement products imported into and manufactured or assembled in South Africa, (iii) to assess using a survey questionnaire the container labelling and other sources of information that assist consumers of nutritional products in their purchasing decisions, (iv) to assess traditional commercial supplements for contamination and consistency of trace elements and heavy metals using Inductively Coupled Plasma-Mass Spectrometry, and (v) to assess the content of nutritional commercial supplements for steroids, stimulants and other compounds of interest using Tandem Liquid Chromatography-Mass Spectrometry.Methods: The thesis is divided into 6 Chapters. Chapter 1 describes the background to the problem and Chapter 2 reviews the existing legislation. In Chapter 3 the labelling and claims information on 40 nutritional supplements products are analysed, and the self-administered questionnaire determined what product label and other information influences consumers of nutritional supplements in their purchasing decisions. In Chapter 4 the consistency of trace elements and heavy metals are analysed in selected nutritional supplements using Inductively Coupled Plasma Mass Spectrometry. In Chapter 5 selected nutritional supplements are analysed for steroids, stimulants and other compounds using Tandem Liquid Chromatography Mass Spectrometry. All the data of these sections are summarised in Chapter 6. en_ZA
dc.language.iso eng en_ZA
dc.subject.other Pharmacology en_ZA
dc.title The investigation and assessment of Nutritional and Traditional Supplement products for content validity, contamination and adulteration en_ZA
dc.type Doctoral Thesis
uct.type.publication Research en_ZA
uct.type.resource Thesis en_ZA
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Health Sciences en_ZA
dc.publisher.department Division of Clinical Pharmacology en_ZA
dc.type.qualificationlevel Doctoral
dc.type.qualificationname Ph D en_ZA
uct.type.filetype Text
uct.type.filetype Image
dc.identifier.apacitation Gabriels, G. A. (2013). <i>The investigation and assessment of Nutritional and Traditional Supplement products for content validity, contamination and adulteration</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Clinical Pharmacology. Retrieved from http://hdl.handle.net/11427/3281 en_ZA
dc.identifier.chicagocitation Gabriels, Gary Anthony. <i>"The investigation and assessment of Nutritional and Traditional Supplement products for content validity, contamination and adulteration."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Clinical Pharmacology, 2013. http://hdl.handle.net/11427/3281 en_ZA
dc.identifier.vancouvercitation Gabriels GA. The investigation and assessment of Nutritional and Traditional Supplement products for content validity, contamination and adulteration. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Clinical Pharmacology, 2013 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/3281 en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Gabriels, Gary Anthony AB - Nutritional supplements are used by competitive and recreational athletes of all ages. As a consequence the supplement industry has grown to meet the increasing demand. The regulation of the supplement industry is unrefined, which increases the risk of the nutritional supplements being contaminated. Contamination may be intentional, where the companies “spike” their products with an ergogenic aid, or unintentional. A consequence of contamination is that an athlete may fail a drug test after ingesting a contaminated supplement or there may be negative health consequences. Without adequate legislation it is difficult to control the industry and reduce the risk of contamination in the supplement. Objectives: To investigate the industry associated with commercially available nutritional and traditional supplements. These are in the five specific areas; (i) to review the regulations and legislations, and labelling and claims associated with nutritional products in the USA, European Union and South Africa, (ii) to assess the labelling and claims information on nutritional supplement products imported into and manufactured or assembled in South Africa, (iii) to assess using a survey questionnaire the container labelling and other sources of information that assist consumers of nutritional products in their purchasing decisions, (iv) to assess traditional commercial supplements for contamination and consistency of trace elements and heavy metals using Inductively Coupled Plasma-Mass Spectrometry, and (v) to assess the content of nutritional commercial supplements for steroids, stimulants and other compounds of interest using Tandem Liquid Chromatography-Mass Spectrometry.Methods: The thesis is divided into 6 Chapters. Chapter 1 describes the background to the problem and Chapter 2 reviews the existing legislation. In Chapter 3 the labelling and claims information on 40 nutritional supplements products are analysed, and the self-administered questionnaire determined what product label and other information influences consumers of nutritional supplements in their purchasing decisions. In Chapter 4 the consistency of trace elements and heavy metals are analysed in selected nutritional supplements using Inductively Coupled Plasma Mass Spectrometry. In Chapter 5 selected nutritional supplements are analysed for steroids, stimulants and other compounds using Tandem Liquid Chromatography Mass Spectrometry. All the data of these sections are summarised in Chapter 6. DA - 2013 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2013 T1 - The investigation and assessment of Nutritional and Traditional Supplement products for content validity, contamination and adulteration TI - The investigation and assessment of Nutritional and Traditional Supplement products for content validity, contamination and adulteration UR - http://hdl.handle.net/11427/3281 ER - en_ZA


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